Steven L Smock

US Patent:

6812002, Nov 2, 2004

Filed:

Aug 30, 2001

Appl. No.:

09/943075

Inventors:

Steven N. Popoff - Warrington PA
Fayez F. Safadi - Philadelphia PA
Thomas A. Owen - East Lyme CT
Steven L. Smock - Baltic CT

Assignee:

Pfizer Inc. - New York NY
Temple Univeristy - Philadelphia PA

International Classification:

C12N 1519

US Classification:

435 691, 4353201, 435325, 435455, 536 231, 536 235

Abstract:

The invention provides osteoactivin proteins and nucleic acid molecules that encode the same, as well as biologically functional expression vectors containing nucleic acid molecules encoding osteoactivin proteins, and antibodies specific for osteoactivin proteins. The invention also provides therapeutic and diagnostic compositions and methods for utilizing the proteins, antibodies, nucleic acids, and vectors of the invention, for example, to modulate bone formation.

US Patent:

7981674, Jul 19, 2011

Filed:

Jan 19, 2007

Appl. No.:

11/655472

Inventors:

Steven N. Popoff - Warrington PA, US
Fayez F. Safadi - Philadelphia PA, US
Thomas A. Owen - East Lyme CT, US
Steven L. Smock - Baltic CT, US

Assignee:

Temple University - Philadelphia PA

International Classification:

C12N 15/00
C12N 5/10
C12N 15/63
C12N 15/12
C12N 15/52

US Classification:

435455, 435 691, 435325, 536 231, 536 232, 536 235

Abstract:

The invention provides osteoactivin proteins and nucleic acid molecules that encode the same, as well as biologically functional expression vectors containing nucleic acid molecules encoding osteoactivin proteins, and antibodies specific for osteoactivin proteins. The invention also provides therapeutic and diagnostic compositions and methods for utilizing the proteins, antibodies, nucleic acids, and vectors of the invention, for example, to modulate bone formation.

US Patent:

20020146777, Oct 10, 2002

Filed:

Aug 30, 2001

Appl. No.:

09/943446

Inventors:

Tessa Castleberry - Groton CT, US
Bihong Lu - Killingworth CT, US
Thomas Owen - East Lyme CT, US
Steven Smock - Baltic CT, US

International Classification:

C07K014/635
C07H021/04
C12N001/18
C12P021/02
C12N005/06

US Classification:

435/069400, 435/254200, 435/325000, 435/320100, 530/399000, 536/023500

Abstract:

The present invention provides isolated canine PTH1 protein, DNA molecules encoding said protein, vectors and cells carrying said DNA molecules, specific bind partners for the protein, and methods of discovering ligands for canine PTH1.

US Patent:

20020161194, Oct 31, 2002

Filed:

Nov 9, 2001

Appl. No.:

10/008739

Inventors:

Tessa Castleberry - Groton CT, US
Bihong Lu - Killingworth CT, US
Thomas Owen - East Lyme CT, US
Steven Smock - Baltic CT, US

International Classification:

C07K001/00
C07K014/00
C07K017/00

US Classification:

530/350000

Abstract:

The present invention provides isolated canine AR protein, DNA molecules encoding said protein, vectors and cells carrying said DNA molecules, specific bind partners for the protein, and methods of discovering ligands for canine AR.

US Patent:

20030059421, Mar 27, 2003

Filed:

Sep 13, 2002

Appl. No.:

10/243501

Inventors:

Tessa Castleberry - Mystic CT, US
Bihong Lu - Killingworth CT, US
Thomas Owen - East Lyme CT, US
Steven Smock - Baltic CT, US

Assignee:

Pfizer Inc.

International Classification:

G01N033/53
C07H021/04
G01N033/567
A61K038/46
C12N009/16
C12P021/02
C12N005/06

US Classification:

424/094600, 435/069100, 435/196000, 435/320100, 435/363000, 536/023200, 435/007200

Abstract:

The present invention provides isolated baboon and cynomolgus macaque EP4 protein, DNA molecules encoding said protein, vectors and cells carrying said DNA molecules, specific bind partners for the protein, and methods of determining ligands for baboon and cynomolgus macaque EP4.

US Patent:

20030059890, Mar 27, 2003

Filed:

Sep 13, 2002

Appl. No.:

10/243351

Inventors:

Tessa Castleberry - Mystic CT, US
Bihong Lu - Killingworth CT, US
Thomas Owen - East Lyme CT, US
Steven Smock - Baltic CT, US

Assignee:

Pfizer Inc.

International Classification:

A61K038/46
C07H021/04
C12N009/16
C12P021/02
C12N005/06

US Classification:

435/069100, 424/094600, 435/196000, 435/320100, 435/325000, 536/023200

Abstract:

The present invention provides isolated chimpanzee EP4 protein, DNA molecules encoding said protein, vectors and cells carrying said DNA molecules, specific binding partners for the protein, and methods of determining ligands for chimpanzee EP4.

US Patent:

20050196772, Sep 8, 2005

Filed:

Nov 1, 2004

Appl. No.:

10/978758

Inventors:

Steven Popoff - Warrington PA, US
Fayez Safadi - Philadelphia PA, US
Thomas Owen - East Lyme CT, US
Steven Smock - Baltic CT, US

International Classification:

C12Q001/68
C07H021/04
C12P021/06
C12N009/64
C12N015/09

US Classification:

435006000, 435069100, 435226000, 435320100, 435325000, 536023200

Abstract:

The invention provides osteoactivin proteins and nucleic acid molecules that encode the same, as well as biologically functional expression vectors containing nucleic acid molecules encoding osteoactivin proteins, and antibodies specific for osteoactivin proteins. The invention also provides therapeutic and diagnostic compositions and methods for utilizing the proteins, antibodies, nucleic acids, and vectors of the invention, for example, to modulate bone formation.