The present invention provides methods and reagents for detecting antibodies to adenovirus. In a preferred embodiment, the present invention is useful for detecting antibodies to adenovirus serotype 5. In a further preferred embodiment, the present invention can be used in a biosensor-based assay. It is contemplated that the present invention is useful to detect antibodies for ascertaining adenovirus infection, evaluating patient response to gene therapy using adenovirus vectors, developing vaccines to adenovirus infection, developing therapeutics for inducing passive immunity to adenovirus infection, as well as other uses.
Detection Of Compounds That Affect Therapeutic Activity
Shuqian Jing - Palo Alto CA, US Francesca Civoli - Newbury Park CA, US Shalini Gupta - Newbury Park CA, US Daniel Halperin - Calabasas CA, US Jason Pennucci - Santa Monica CA, US Steven Swanson - Moorpark CA, US Yan Yu - Thousand Oaks CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C12Q 1/68 G01N 33/53
US Classification:
435006000, 435007100
Abstract:
The present invention relates to methods of detecting compounds that affect the activity of a therapeutic substance or composition administered to a subject, and to reagents for use in such methods.
Immunocellular Therapeutics Ltd Feb 2015 - Nov 2018
Senior Vice President, Research
Steven J Swanson Consulting Nov 2014 - Feb 2015
Immunogenicity Consultant
Amgen May 1999 - Nov 2014
Executive Director
Schering-Plough Research Institute 1991 - 1999
Senior Principal Scientist
1991 - 1999
Moorpark, California
Education:
The Ohio State University 1988 - 1991
Associates, Immunology
University of Iowa 1981 - 1987
Doctorates, Doctor of Philosophy, Microbiology
North Central College 1973 - 1977
Bachelors, Bachelor of Arts, Biology, Chemistry
Skills:
Biomarkers Antibodies Monoclonal Antibodies Bioanalysis Ind Immunogenicity Biosimilars Management Cro Validation Drug Discovery Immunoassays Assay Development Lifesciences Drug Development Biotechnology Pharmaceutical Industry Translational Research Toxicology Translational Medicine Biopharmaceuticals Protein Chemistry Glp Immunology Regulatory Submissions Clinical Development Elisa Technology Transfer Oncology Team Leadership Clinical Trials Biochemistry Life Sciences
Robert Frost Elementary School Mt. Prospect IL 1972-1977, Dempster Junior High School Mt. Prospect IL 1977-1979, Rand Junior High School Arlington Heights IL 1979-1980
Community:
Michael Cozzarelli, William Brisker, Jeff Curtiss, Melanie Jessop
Eugene Field Elementary School Park Ridge IL 1964-1968
Community:
Kari Hadley, Craig Miller, Gary Sheehan, Christine Sloper, Lee Carpenter, Thomas Wilke, Kimberly Graves, Jan Xelowski, Cyndie Graf, Wendy Miller, Nicki Galli, Robert Graf
When Wiseman and former crewmate Steven Swanson, a NASA astronaut, appeared before the committee live from the space station in July, Edwards pledged to send some freeze-dried crab cakes to the station. The promise drew a smile and a fist pump from Wiseman, who is a commander in the U.S. Navy.
A Russian Soyuz capsule carrying Oleg Artemiev, Alexander Skvortsov and Steven Swanson parachuted safely onto the steppe of Kazakhstan early Thursday morning, several hours after ending a nearly six-month mission aboard the ISS. They have been replaced by a new three-person crew, including Russian c
Date: Sep 11, 2014
Source: Google
International Space Station Astronauts Return To Earth After Record-Breaking ...
"We did lots of cargo, we did lots of science" NASA station commander Steven Swanson said after his return to Earth. "We actually set the record for the number of hours of science in a week. We did a lot of maintenance, which is good and bad; I love doing maintenance, but it means things broke."
Date: Sep 11, 2014
Category: Sci/Tech
Source: Google
Public Invited to Kennedy Space Centre to Celebrate 45th Anniversary of Moon ...
The event at the Kennedy Space Centre will feature crew members of Apollo 11, namely Michael Collins, astronaut Jim Lovell and NASA administer Charles Bolden. Orbiting in their lab 260 miles above the Earth, Reid Wiseman and Steven Swanson will also take part in the event. It will air on Monday, Jul
Date: Jul 18, 2014
Category: Sci/Tech
Source: Google
Public invited to celebrate 45th anniversary of first moon walk
enter will feature Apollo 11 crewmembers Michael Collins, astronaut Jim Lovell, and NASA administer Charles Bolden. Orbiting in their lab 260 miles above Earth, Reid Wiseman and Steven Swanson, the current station commander, will also take part in the event, which will air on Monday, July 21 at 10 a.
A private cargo ship launched three days ago from Virginia arrived at the orbiting complex a little after 6:30 a.m. EDT. The stations commander, Steven Swanson, used a giant robot arm to grab onto the Cygnus capsule and its precious load as the craft zoomed 260 miles above northern Libya.
astern Shore of Virginia arrived at the orbiting complex a little after 6:30 a.m. EDT. The station's commander, Steven Swanson, used a giant robot arm to grab onto the Cygnus capsule and its precious load as the craft zoomed 260 miles above northern Libya; the vast expanse of sand provided a backdrop.
days ago from Virginia arrived at the orbiting complex a little after 6:30 a.m. EDT. The station's commander, Steven Swanson, used a giant robot arm to grab onto the Cygnus capsule and its precious load as the craft zoomed 260 miles above northern Libya; the vast expanse of sand provided a backdrop.