Stewart H Lecker from 237 Winchester St APT 2, Brookline, MA 02446, age 61, Phone: (617)7392759

Dr. Stewart H Lecker - MD (Doctor of Medicine)

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Hospitals:

185 Pilgrim Rd Suite Farr8, Boston, MA 02215

Beth Israel Deaconess Medical Center
330 Brookline Avenue, Boston, MA 02215

Education:

Medical Schools
David Geffen School Of Medicine At UCLA, University Of California, Los Angeles
Graduated: 1992

Stewart H. Lecker

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Specialties:

Nephrology

Work:

Beth Israel Deaconess Medical Center Nephrology
185 Pilgrim Rd Lbby 2, Boston, MA 02215
(617)6329880 (phone), (617)6329890 (fax)

Beth Israel Deaconess Medical Center
185 Pilgrim Rd STE FARR8, Boston, MA 02215
(617)6329880 (phone), (617)6329890 (fax)

Education:

Medical School
University of California, Los Angeles David Geffen School of Medicine
Graduated: 1992

Procedures:

Dialysis Procedures

Conditions:

Chronic Renal Disease
Acute Glomerulonephritis
Acute Renal Failure
Nephrotic Syndrome

Languages:

English
Russian

Description:

Dr. Lecker graduated from the University of California, Los Angeles David Geffen School of Medicine in 1992. He works in Boston, MA and 1 other location and specializes in Nephrology. Dr. Lecker is affiliated with Beth Israel Deaconess Medical Center West Campus.

Stewart H Lecker, Boston MA

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Specialties:

Nephrologist

Address:

185 Pilgrim Rd, Boston, MA 02215

Education:

UCLA, David Geffen School of Medicine - Doctor of Medicine
Beth Israel Deaconess Medical Center - Fellowship - Nephrology (Internal Medicine)
Ronald Reagan UCLA Medical Center - Residency - Internal Medicine

Board certifications:

American Board of Internal Medicine Certification in Internal Medicine
American Board of Internal Medicine Sub-certificate in Nephrology (Internal Medicine)

Us Patents

Methods And Reagents Related To Foxo
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US Patent:

20060069049, Mar 30, 2006
Filed:

Dec 28, 2004
Appl. No.:

11/024371
Inventors:

Alfred Goldberg - Chestnut Hill MA, US
Stewart Lecker - Brookline MA, US
Marco Sandri - Boston MA, US
Assignee:

President and Fellows of Harvard College - Cambridge MA
International Classification:

A61K 48/00
C12Q 1/68
US Classification:

514044000, 435006000
Abstract:

The present invention relates to regulating the activity of Foxo and prevention and treatment of diseases associated with aberrant Foxo activity.

Methods And Compositions For The Treatment And Diagnosis Of Statin-Induced Myopathy
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US Patent:

20100310574, Dec 9, 2010
Filed:

Jun 5, 2008
Appl. No.:

12/663423
Inventors:

Vikas P. Sukhatme - Newton MA, US
Stewart H. Lecker - Brookline MA, US
Junichi Hanai - Boston MA, US
Assignee:

Beth Israel Deaconess Medical Center - Boston MA
International Classification:

A61K 39/395
A61K 38/02
A61K 31/675
A61K 31/7105
G01N 33/68
C12Q 1/68
G01N 33/566
G01N 33/53
C12N 5/07
A61P 21/00
US Classification:

4241581, 514 11, 514 81, 514 44 A, 435 71, 435 6, 436501, 436 86, 436 94, 435375
Abstract:

The invention provides compositions and kits containing an atrogin-1 inhibitor compound useful for the treatment of a statin-mediated myopathy. Kits for the diagnosis of a statin-mediated myopathy are also provided. The invention further features methods for treating or preventing a statin-mediated myopathy in a subject via administration of a therapeutically effective amount of an atrogin-1 inhibitor compound. The invention further provides methods of diagnosing a subject as having a propensity to develop a statin-induced myopathy and methods of monitoring a statin-induced myopathy or a propensity to develop a statin-mediated myopathy in a subject. The invention also features methods for identifying a compound for the treatment of a statin-mediated myopathy and methods of identifying a statin compound as having the propensity to induce a statin-mediated myopathy.

Methods And Compositions For The Treatment And Diagnosis Of Statin-Induced Myopathy
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US Patent:

20120171286, Jul 5, 2012
Filed:

Apr 27, 2010
Appl. No.:

13/266355
Inventors:

Vikas P. Sukhatme - Newton MA, US
Stewart H. Lecker - Brookline MA, US
Jun-ichi Hanai - Boston MA, US
Assignee:

Beth Isreal Deaconess Medical Center - Boston MA
International Classification:

A61K 9/20
A61K 31/19
A61K 31/66
A61K 31/366
US Classification:

424464, 514460, 514557, 514106
Abstract:

Disclosed are methods for treating or preventing a statin-mediated myopathy in a subject via administration of a therapeutically effective amount of a geranylgeranylation activator. Further disclosed are kits containing a geranylgeranylation activator useful for the treatment of a statin-mediated myopathy.

Compositions And Methods For Treatment Of Muscle Wasting
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US Patent:

20030077288, Apr 24, 2003
Filed:

Jan 16, 2002
Appl. No.:

10/050686
Inventors:

Alfred Goldberg - Chestnut Hill MA, US
Marcelo Gomes - Brookline MA, US
Stewart Lecker - Brookline MA, US
R. Jagoe - Ellesmere, GB
International Classification:

A61K038/43
C07K014/435
US Classification:

424/185100, 424/094100, 530/350000
Abstract:

The present invention relates to the isolation of cell- or tissue-specific F-box proteins which are involved in ubiquitin-mediated protein degradation in a specific cell- or tissue-type. Accordingly, the invention provides nucleic acids and the proteins encoded by said nucleic acids which play a role in the ubiquitinylation and subsequent degradation of substrate proteins and in regulating cell proliferation, cell differentiation, and cell survival. The invention also provides methods for modulating protein degradation, cell proliferation, cell differentiation and/or cell survival by modulating protein ubiquitination; assays for identifying compounds which modulate protein degradation, cell proliferation, differentiation and/or cell survival; methods for treating disorders associated with aberrant protein degradation, cell proliferation, cell differentiation, and/or cell survival; and diagnostic and prognostic assays for determining whether a subject is at risk of developing a disorder associated with an aberrant protein degradation, cell proliferation, cell differentiation, and/or survival.