Susan E Baldwin

US Patent:

6756032, Jun 29, 2004

Filed:

Jul 12, 2000

Appl. No.:

09/614669

Inventors:

Bruce Ernest Tepper - Cincinnati OH
Susan Baldwin - Cincinnati OH
Scott Edward Osborne - Middletown OH
Mauricio Odio - Gahanna OH

Assignee:

The Procter Gamble Company - Cincinnati OH

International Classification:

A61B 1000

US Classification:

424 98, 424 981, 435 29, 530859, 600306, 600307, 600556

Abstract:

The present invention relates to a method comprising subjecting a test site of a responsive system to a primary challenge; subjecting the same test site to a secondary challenge, wherein the secondary challenge is designed to enhance and/or prolong a response of the responsive system to the primary challenge, without confounding the response nor altering the mechanism by which the primary challenge elicits a response from the responsive system; and assessing the response subsequent to the secondary challenge. The methods claimed herein also preferably comprise the additional step(s) of subjecting test site(s) to one or more pre-challenge intervention(s) and/or post-challenge intervention(s) and/or concurrent-challenge intervention(s). The methods of the present invention are also useful in a study design, also claimed herein, wherein the study comprises the steps of the method outlined above in addition to comprising the steps of creating one or more controls selected from the group consisting of negative controls, primary controls, secondary controls, positive controls, and mixtures thereof. The use of the novel methods described herein often significantly shorten the duration of and/or number of subjects needed for studies aimed at understanding the etiology of a disease and/or the ability of a intervention or challenge to prevent, cure, heal, and/or reduce and/or induce damage or injury to a responsive system.

US Patent:

7229778, Jun 12, 2007

Filed:

Feb 26, 2004

Appl. No.:

10/787560

Inventors:

Stephen Worth Hendrix - Clarksville OH, US
Scott Edward Osborne - Liberty Township OH, US
Susan Baldwin - Cincinnati OH, US

Assignee:

The Procter & Gamble Company - Cincinnati OH

International Classification:

G01N 33/53
G01N 33/567

US Classification:

435 72

Abstract:

A method for determining the relative benefits of products which affect animal epithelial tissue is provided. Also provided is a method for evaluating quantitative changes on one or more affected surfaces of epithelial tissue of a subject caused by a test product.

US Patent:

7763419, Jul 27, 2010

Filed:

Apr 25, 2007

Appl. No.:

11/789648

Inventors:

Stephen Worth Hendrix - Clarksville OH, US
Scott Edward Osborne - Liberty Township OH, US
Susan Baldwin - Cincinnati OH, US

Assignee:

The Procter & Gamble Company - Cincinnati OH

International Classification:

C12Q 1/00
G01N 33/53
G01N 33/567

US Classification:

435 4, 435 71, 435 72

Abstract:

A method for determining the relative benefits of products which affect animal epithelial tissue is provided. Also provided is a method for evaluating quantitative changes on one or more affected surfaces of epithelial tissue of a subject caused by a test product.

US Patent:

7771924, Aug 10, 2010

Filed:

Apr 25, 2007

Appl. No.:

11/789650

Inventors:

Stephen Worth Hendrix - Clarksville OH, US
Scott Edward Osborne - Liberty OH, US
Susan Baldwin - Cincinnati OH, US

Assignee:

The Procter & Gamble Company - Cincinnati OH

International Classification:

C12Q 1/00
G01N 33/53
G01N 33/567

US Classification:

435 4, 435 71, 435 72

Abstract:

A method for determining the relative benefits of products which affect animal epithelial tissue is provided. Also provided is a method for evaluating quantitative changes on one or more affected surfaces of epithelial tissue of a subject caused by a test product.

US Patent:

7771925, Aug 10, 2010

Filed:

Apr 25, 2007

Appl. No.:

11/789766

Inventors:

Stephen Worth Hendrix - Clarksville OH, US
Scott Edward Osborne - Liberty OH, US
Susan Baldwin - Cincinnati OH, US

Assignee:

The Procter & Gamble Company - Cincinnati OH

International Classification:

C12Q 1/00
G01N 33/53
G01N 33/567

US Classification:

435 4, 435 71, 435 72

Abstract:

A method for determining the relative benefits of products which affect animal epithelial tissue is provided. Also provided is a method for evaluating quantitative changes on one or more affected surfaces of epithelial tissue of a subject caused by a test product.

US Patent:

20020026165, Feb 28, 2002

Filed:

Sep 10, 1997

Appl. No.:

08/926532

Inventors:

GRETCHEN LOUISE ELDER - CINCINNATI OH, US
LAURA G. S. VAN RIJSWIJCK - CINCINNATI OH, US
SUSAN BALDWIN - CINCINNATI OH, US
MAURICIO R. ODIO - CINCINNATI OH, US
MICHELLE DENISE ROSEMAN - CINCINNATI OH, US
DONALD ROE - West Chester OH, US

International Classification:

A61F013/15
A61F013/20

US Classification:

604/364000, 424/402000, 604/360000

Abstract:

Disclosed is a method for maintaining and/or improving skin health in the area of a wearer covered by an absorbent article, the method comprising: (a) applying to the wearer an absorbent article having a skin care composition that provides a therapeutic and/or protective skin benefit upon transfer to the skin; (b) transferring to the wearer at least a portion of the skin care composition during wear; and (c) repeating steps (a) and (b) with one or more additional articles with sufficient frequency to maintain or improve the skin covered by the absorbent article relative to skin covered by an equivalent absorbent article that does not comprise the skin care composition, and without the need for manual application of skin protective agents (e.g., by the caregiver or wearer). Also disclosed are detailed methods for assessing skin health.

US Patent:

20070202489, Aug 30, 2007

Filed:

Apr 25, 2007

Appl. No.:

11/789649

Inventors:

Stephen Hendrix - Clarksville OH, US
Scott Osborne - Liberty OH, US
Susan Baldwin - Cincinnati OH, US

International Classification:

C12Q 1/00

US Classification:

435004000

Abstract:

A method for determining the relative benefits of products which affect animal epithelial tissue is provided. Also provided is a method for evaluating quantitative changes on one or more affected surfaces of epithelial tissue of a subject caused by a test product.