Susan D Burke

US Patent:

8119112, Feb 21, 2012

Filed:

Sep 3, 2008

Appl. No.:

12/203384

Inventors:

Erning Xia - Penfield NY, US
Susan E. Burke - Batavia NY, US
Srini Venkatesh - Pittsford NY, US
Vicki Barniak - Fairport NY, US

Assignee:

Bausch & Lomb Incorporated - Rochester NY

International Classification:

A61K 31/74

US Classification:

424 7804, 514912

Abstract:

Ophthalmic compositions that comprise 0. 1 ppm to 10 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0. 005 wt. % to 0. 15 wt. % of hyaluronic acid; and 0. 01 wt. % to 1. 0 wt. % of an amphoteric surfactant of general formula I.

US Patent:

8283463, Oct 9, 2012

Filed:

Feb 9, 2010

Appl. No.:

12/702540

Inventors:

David J. Heiler - Avon NY, US
Thomas Menzel - Rochester NY, US
Abbie Brongo - Victor NY, US
Susan E. Burke - Batavia NY, US
Karl Cummins - Hilton NY, US

Assignee:

Bausch & Lomb Incorporated - Rochester NY

International Classification:

C07H 5/06
C08B 37/00

US Classification:

536 552, 536 55, 536127, 514 54

Abstract:

A process for sterilizing a solution comprising hyaluronic acid. The process comprises providing an aqueous solution of hyaluronic acid with a weight average molecular weight from 0. 6 MDa to 3. 6 MDa, and the concentration of the hyaluronic acid is from 0. 04% to 0. 8% by weight. The aqueous solution also has an ionic strength equivalent to an aqueous concentration of sodium chloride from 3% to 30% by weight. Once the aqueous, high salt, hyaluronic acid solution is prepared the solution is maintained at a temperature from 40 C. to 80 C. for at least 1 hour and not longer than six days. Following the heat treatment step, the aqueous solution is filtered through a sterilization filter medium to provide a sterilized high salt, hyaluronic acid solution.

US Patent:

8530641, Sep 10, 2013

Filed:

Aug 1, 2012

Appl. No.:

13/564161

Inventors:

David J. Heiler - Avon NY, US
Thomas Menzel - Rochester NY, US
Abbie Brongo - Victor NY, US
Susan E. Burke - Batavia NY, US
Karl Cummins - Hilton NY, US

Assignee:

Bausch & Lomb Incorporated - Rochester NY

International Classification:

A61K 31/728
C08B 37/00
C08B 37/08

US Classification:

536 551, 514 54

Abstract:

Sterilized aqueous solution comprising 0. 04% to 0. 8% by weight hyaluronic acid with a weight average molecular weight from 0. 6 MDa to 3. 6 MDa, and one or more buffer components selected from the group consisting of boric acid, sodium borate and sodium dihydrogen phosphate. The aqueous solution also has an ionic strength equivalent to an aqueous concentration of sodium chloride from 4% to 18% by weight of sodium chloride and a pH from 6. 4 to 7. 2. The solution is also filtered through a filter medium that has an average pore size of 0. 25 μm or less to provide a sterilized high salt, hyaluronic acid solution.

US Patent:

20070149428, Jun 28, 2007

Filed:

Dec 13, 2006

Appl. No.:

11/610372

Inventors:

Daniel Ammon - Penfield NY, US
Jay Kunzler - Canandaigua NY, US
Joseph Salamone - Boca Raton FL, US
Susan Burke - Batavia NY, US
Ronald Koch - Webster NY, US
Jeffrey Linhardt - Fairport NY, US

Assignee:

BAUSCH & LOMB INCORPORATED - Rochester NY

International Classification:

A61L 2/00
C08K 5/00

US Classification:

510112000, 206005100

Abstract:

A contact lens package includes a sealed receptacle containing a contact lens immersed in a sterile solution. The contact lens is made of a silicone hydrogel copolymer, and the solution includes a stabilizing agent in an amount effective to inhibit changes in physical properties of the silicone hydrogel copolymer.

US Patent:

20080031772, Feb 7, 2008

Filed:

Jun 28, 2007

Appl. No.:

11/770110

Inventors:

David J. Heiler - Avon NY, US
Pramod Kumar Gupta - Pittsford NY, US
Susan E. Burke - Batavia NY, US
Suzanne F. Groemminger - Rochester NY, US

International Classification:

A61L 12/14
C11D 3/48

US Classification:

422 28, 510112

Abstract:

A method of making a disinfecting solution that is effective at disinfecting contact lenses. The method includes the step of combining water, one or more antimicrobial agents and a reduced amount of solid content into a dissolved liquid mixture. The process results in an improved disinfection efficacy compared to a reference solution.

US Patent:

20090126318, May 21, 2009

Filed:

Oct 27, 2008

Appl. No.:

12/258938

Inventors:

Sanjay M. Rastogi - Rochester NY, US
Susan E. Burke - Batavia NY, US
Thomas Menzel - Rochester NY, US

International Classification:

B65B 55/02
B65B 1/04
A45C 11/04

US Classification:

53425, 53467, 206 51

Abstract:

A packaging system for the storage of a hydrogel contact lens employs an aqueous solution including hydroxypropyl methylcellulose.

US Patent:

20090196845, Aug 6, 2009

Filed:

Jan 31, 2008

Appl. No.:

12/023509

Inventors:

Erning Xia - Penfield NY, US
Susan E. Burke - Batavia NY, US
Vicki Barniak - Fairport NY, US
Praveen Tyle - Pittsford NY, US

International Classification:

A01N 47/44
A01P 1/00
A01N 33/12
C11D 1/00

US Classification:

424 7804, 514635, 514642, 510112

Abstract:

Ophthalmic compositions that comprise 0.1 ppm to 50 ppm of a cationic antimicrobial component selected from the group consisting of biguanides, polymeric biguanides, quaternium ammonium compounds and any one mixture thereof; 0.005 wt. % to 2 wt. % of an anionic biopolymer; and 0.01 wt. % to 2 wt. % of an amphoteric surfactant of general formula I

US Patent:

20100104528, Apr 29, 2010

Filed:

Oct 7, 2009

Appl. No.:

12/574732

Inventors:

Zora Marlowe - Rochester NY, US
Hongna Wang - Ontario NY, US
Susan E. Burke - Batavia NY, US

International Classification:

A01N 37/52
A01P 1/00
A01N 33/12
A01N 59/00

US Classification:

424 7808, 514635, 514642, 424616

Abstract:

An aqueous contact lens solution comprising less than 100 ppm of a tertiary amine oxide of general formula