Susan J. Drapeau - Cordova TN, US Kathy L. Chamness - Memphis TN, US William F. McKay - Memphis TN, US
Assignee:
Warsaw Orthopedic, Inc
International Classification:
A61F 2/28
US Classification:
424423, 424488
Abstract:
Described are medical implant devices that include particulate collagen and particulate demineralized bone matrix. These and potentially other materials are held together in a three-dimensionally stable structure such as a porous, resilient sheet, by an ionically-crosslinked polysaccharide gel. Also described are methods for making and using such medical devices.
Malleable Implants Containing Demineralized Bone Matrix
Susan J. Drapeau - Cordova TN, US Kathy L. Chamness - Memphis TN, US William F. McKay - Memphis TN, US
International Classification:
A61F 2/28 A61K 35/32
US Classification:
424423, 424488, 424489, 424549, 523115, 623 2361
Abstract:
Described are malleable medical compositions such as pastes or putties that include solids combined with a liquid carrier. The solids include particulate collagen and particulate demineralized bone matrix. The liquid carrier includes an aqueous medium comprising a polysaccharide. Also described are methods for making and using such medical compositions.
William F. McKay - Memphis TN, US Susan J. Drapeau - Cordova TN, US
International Classification:
A61M 5/00
US Classification:
604173, 604191, 604239
Abstract:
Described are novel methods for delivering a medical agent to a plurality of locations within a patient tissue volume such as the interior space of a spinal disc, and also for removing material therefrom during medical agent delivery to enhance the delivery. Also described are medical delivery devices such as needle assemblies configured to facilitate the regional delivery of medical agents to patient tissue.
Variable Opening Delivery System For Intervertebral Disc Therapies
The disclosure is directed to a needle system configured to enlarge an access path in a patient without further cutting into the tissue of the patient so as to reduce recovery time and trauma to the patient. Also provided are methods of using the needle system provided.
Intracellular Delivery Of Osteoinductive Proteins And Peptides
Frances Louisa Titus - Atlanta GA, US Jeffrey C. Marx - Germantown TN, US Scott D. Boden - Atlanta GA, US Susan Drapeau - Cordova TN, US
International Classification:
A01N 63/00 C12N 5/00 C12N 15/00
US Classification:
424 9321, 435455, 435325
Abstract:
The invention provides fusion polypeptides comprising protein transduction domains and osteoinductive polypeptides, as well as methods of using such polypeptides to induce osteogenesis and to promote proteoglycan synthesis. The invention also provides osteoinductive peptides which have demonstrated the ability to induce bone formation in vivo.
Method For Enhancing The Viability Of Mammalian Cells, Tissues And Organs Using A Solution Comprising Two Low Molecular Weight Pegs
Daniel A. Shimko - Germantown TN, US Scott Noel - Memphis TN, US Susan J. Drapeau - Cordova TN, US Josee Roy - Memphis TN, US
International Classification:
A01N 1/00
US Classification:
435 11
Abstract:
Disclosed are compositions and methods for the preservation, storage, and transport of living biological tissues, organs, and populations of isolated cells. In particular, the disclosed compositions and processes permit mammalian cells, tissues, and organs to be harvested from suitable donor animals, stored for prolonged periods, and transported to the site of recipient implantation, all without significant loss of cell viability, biological activity, and/or tissue integrity.
Methods And Compositions For The Preservation Of Cells And Tissues
Josee Roy - Memphis TN, US Susan J. Drapeau - Cordova TN, US Daniel A. Shimko - Germantown TN, US
Assignee:
Warsaw Orthoperic, Inc. - Warsaw IN
International Classification:
A01N 1/00
US Classification:
435 2, 435 11
Abstract:
Disclosed are methods for the preservation and storage of living biological tissues, organs, and populations of isolated cells. Also disclosed are compositions and methods to permit biological samples (including e. g. , cells, cell cultures, tissues, and organs) to be harvested from suitable donor animals, stored for prolonged periods under refrigerated, cryogenic, or near-freezing, and then transported and implanted into a site within the body of a selected recipient animal, all without significant loss of cellular viability, tissue integrity, and/or biochemical function of the stored biological sample.
William F. McKay - Memphis TN, US Susan J. Drapeau - Cordova TN, US
Assignee:
Warsaw Orthopedic, Inc. - Warsaw IN
International Classification:
A61M 1/00 A61M 31/00 A61M 5/00
US Classification:
604506, 604 28, 604173, 604191, 604239
Abstract:
Described are novel methods for delivering a medical agent to a plurality of locations within a patient tissue volume such as the interior space of a spinal disc, and also for removing material therefrom during medical agent delivery to enhance the delivery. Also described are medical delivery devices such as needle assemblies configured to facilitate the regional delivery of medical agents to patient tissue.
Medtronic since Aug 2010
Director, Biologics R&D
Medtronic Jul 2008 - Aug 2010
Senior Manager, Biologics R&D
Medtronic Jun 2005 - Jun 2008
Manager, Biologics R&D
Medtronic Nov 2001 - Jun 2005
Biologic Project Leader
Osiris Therapeutics Mar 2001 - Nov 2001
Sr. Manager, Bone Products
Education:
Rice University 1994 - 1998
PhD, Chemical EngineeringThesis Advisor: Dr. Antonios Mikos
Purdue University 1990 - 1994
BS, Chemisty
Purdue University 1990 - 1994
BS, Chemical Engineering
Skills:
R&D Medical Devices Fda Biologics Design Control Biotechnology Iso 13485 Leadership Commercialization Cross Functional Team Leadership Product Development Capa Product Launch Bone Quality System Biomedical Engineering Validation V&V Research and Development Market Development U.s. Food and Drug Administration Quality Control Spc Regulatory Affairs Design of Experiments Iso 14971 Verification and Validation Product Management Corrective and Preventive Action Business Development Strategy