Susan Louise Harlocker

US Patent:

6395278, May 28, 2002

Filed:

Jul 13, 1999

Appl. No.:

09/352616

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Redmond WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Jiang Yuqiu - Kent WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

A61K 3848

US Classification:

4241921, 4241851, 424 9464, 435212, 530403

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate tumor protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6512094, Jan 28, 2003

Filed:

Jun 13, 2000

Appl. No.:

09/593793

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07K 100

US Classification:

530350, 435 911, 435 912, 435 5, 435 6, 42419711, 4241841, 4241851, 536 231, 536 237, 530352, 530380

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6528054, Mar 4, 2003

Filed:

Jul 20, 2000

Appl. No.:

09/620405

Inventors:

Yuqiu Jiang - Kent WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Jiangchun Xu - Bellevue WA
Susan L. Harlocker - Seattle WA
William T. Hepler - Seattle WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

A61K 39395

US Classification:

4241301, 5303871

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as breast cancer, are disclosed. Compositions may comprise one or more breast tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a breast tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as breast cancer. Diagnostic methods based on detecting a breast tumor protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6579973, Jun 17, 2003

Filed:

Nov 3, 1999

Appl. No.:

09/433826

Inventors:

Jiang Yuqiu - Kent WA
Davin C. Dillon - Redmond WA
Jennifer L. Mitcham - Redmond WA
Jiangchun Xu - Bellevue WA
Susan L. Harlocker - Seattle WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07K 100

US Classification:

530806, 530350

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as breast cancer, are disclosed. Compositions may comprise one or more breast tumor proteins, immunogenic portion thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a breast tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as breast cancer. Diagnostic methods based on detecting a breast tumor protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6586572, Jul 1, 2003

Filed:

Jun 22, 2000

Appl. No.:

09/604287

Inventors:

Yuqiu Jiang - Kent WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Jiangchun Xu - Bellevue WA
Susan L. Harlocker - Seattle WA
William T. Hepler - Seattle WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07K 1100

US Classification:

530350, 5303873

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as breast cancer, are disclosed. Compositions may comprise one or more breast tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a breast tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as breast cancer. Diagnostic methods based on detecting a breast tumor protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6620922, Sep 16, 2003

Filed:

Aug 9, 2000

Appl. No.:

09/636215

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C07H 2104

US Classification:

536 231, 536 234, 536 241, 536 2431, 536 2433, 536 235, 435 6, 435 911

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.

US Patent:

6630305, Oct 7, 2003

Filed:

Oct 10, 2000

Appl. No.:

09/685166

Inventors:

Jiangchun Xu - Bellevue WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Susan L. Harlocker - Seattle WA
Yuqiu Jiang - Kent WA
Michael D. Kalos - Seattle WA
Gary R. Fanger - Mill Creek WA
Marc W. Retter - Carnation WA
John A. Stolk - Bothell WA
Craig H. Day - Seattle WA
Thomas S. Vedvick - Federal Way WA
Darrick Carter - Seattle WA
Samuel X. Li - Redmond WA
Aijun Wang - Issaquah WA
Yasir A. W. Skeiky - Bellevue WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C12Q 168

US Classification:

435 6, 4353201, 4352523, 435325, 536 231, 536 241

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.

US Patent:

6680197, Jan 20, 2004

Filed:

Apr 13, 2001

Appl. No.:

09/834759

Inventors:

Yuqiu Jiang - Kent WA
Davin C. Dillon - Issaquah WA
Jennifer L. Mitcham - Redmond WA
Jiangchun Xu - Bellevue WA
Susan L. Harlocker - Seattle WA
William T. Hepler - Seattle WA
Robert A. Henderson - Edmonds WA

Assignee:

Corixa Corporation - Seattle WA

International Classification:

C12N 508

US Classification:

435325, 4353201, 536 243, 536 2431, 536 2433

Abstract:

Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.