Susan B Lindquist

age ~82

from Kennebunk, ME

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Also known as:

Susan G Lindquist
Susan B Garvey
Susan L Garvey
Susan B Linquist
Sue Lindquist
Susan E
Susan Y
Susan A

Phone and address:: 16 Oakwood Ln, Kennebunk, ME 04043
(207)4673410

Connected to:

Susan Lindquist Phones & Addresses

16 Oakwood Ln, Kennebunk, ME 04043 • (207)4673410
21 Rosewood Cir, Kennebunk, ME 04043
Bradenton, FL
22 Broad Oak Way, Hanover, MA 02339
Kennebunkport, ME
Duxbury, MA
Sandwich, MA
East Sandwich, MA
Seattle, WA

Work

Company:

Whitehead institute for bio-medical research
Address:

9 Cambridge Ctr, Cambridge, MA 02142
Phones:

(617)2585000
Position:

Director
Industries:

Noncommercial Research Organizations

Education

School / High School:

Temple University
1974

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate:

Internal Medicine, 1984

Specialities

Internal Medicine

Medicine Doctors

Dr. Susan M Lindquist, Cambridge MA - MD (Doctor of Medicine)

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Specialties:

Internal Medicine

Address:

9 Cambridge Ctr Suite 657, Cambridge, MA 02142
(617)2585184 (Phone)

Certifications:

Internal Medicine, 1984

Awards:

Healthgrades Honor Roll

Languages:

English

Education:

Medical School
Temple University
Graduated: 1974
Medical School
Fulkner-Shattuck Hosps
Graduated: 1974
Medical School
Baystate Mc
Graduated: 1974
Medical School
Yale University
Graduated: 1974

Isbn (Books And Publications)

Wander

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Author
Susan Hart Lindquist

ISBN #
0385325630

Summer Soldiers

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Author
Susan Hart Lindquist

ISBN #
0385326416

Wander

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Author
Susan Hart Lindquist

ISBN #
0440414431

Stress-Induced Proteins: Proceedings of a Hoffmann-La Roche-Director's Sponsors-UCLA Symposium, Held at Keystone, Colorado, April 10-16, 1988

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Author
Susan Lindquist

ISBN #
0845126954

Name / Title

Company / Classification

Phones & Addresses

Susan Lindquist
Director

Whitehead Institute For Bio-Medical Research
Noncommercial Research Organizations

9 Cambridge Ctr, Cambridge, MA 02142

Us Patents

Yeast Screens For Treatment Of Human Disease
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US Patent:

7045290, May 16, 2006
Filed:

Feb 15, 2002
Appl. No.:

10/077584
Inventors:

Susan Lindquist - Chestnut Hill MA, US
Sylvia Krobitsch - Berlin, DE
Tiago Fleming Outeiro - Cambridge MA, US
Assignee:

The University of Chicago - Chicago IL
International Classification:

C12Q 1/68
US Classification:

435 6
Abstract:

Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes.

Yeast Screens For Treatment Of Human Disease
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US Patent:

8039209, Oct 18, 2011
Filed:

Feb 27, 2006
Appl. No.:

11/363870
Inventors:

Susan Lindquist - Chestnut Hill MA, US
Sylvia Krobitsch - Berlin, DE
Tiago Fleming Outeiro - Cambridge MA, US
Assignee:

The University of Chicago - Chicago IL
International Classification:

C12Q 1/68
US Classification:

435 6, 43525411, 43525421
Abstract:

Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes.

Compositions And Methods For Treatment Of Protein Misfolding Diseases
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US Patent:

8192986, Jun 5, 2012
Filed:

May 4, 2005
Appl. No.:

11/568653
Inventors:

Susan L. Lindquist - Chestnut Hill MA, US
Martin Duennwald - Cambridge MA, US
Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:

C12Q 1/00
C12Q 1/02
G01N 33/53
US Classification:

435375, 435 72, 435 4, 435 29
Abstract:

Disclosed are methods for identifying compounds that modulate huntingtin mediated impairment of protein degradation pathways. Compounds identified by such screens can be used as candidate drugs for the treatment of prevention of polyglutamine diseases such as Huntington's Disease.

Hsp90, Buffering And Drug Resistance
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US Patent:

8343913, Jan 1, 2013
Filed:

Jul 5, 2005
Appl. No.:

11/175515
Inventors:

Leah Cowen - Jamaica Plain MA, US
Susan L. Lindquist - Chestnut Hill MA, US
Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:

A01N 37/18
A01N 43/64
A61K 38/00
A61K 31/41
A61K 45/00
A61K 47/44
A61P 31/10
C07D 293/00
C07D 421/00
C07D 517/00
C07D 291/00
C07D 419/00
C07D 515/00
C07D 285/00
C07D 417/00
C07D 513/00
C07D 273/00
C07D 413/00
C07D 498/00
C07D 277/04
C07D 277/08
C07D 275/02
C07D 249/08
C07D 233/00
C07D 233/02
C07D 231/00
US Classification:

514 33, 514359, 4242831, 548100, 548122, 548123, 548124, 548146, 548206, 548240, 5482622, 5483001, 5483561
Abstract:

A method of reducing antifungal drug resistance in which Hsp inhibitors, such as Hsp90 inhibitors, are used.

Modulators Of Alpha-Synuclein Toxicity
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US Patent:

8399241, Mar 19, 2013
Filed:

Dec 1, 2005
Appl. No.:

11/720586
Inventors:

Susan L. Lindquist - Chestnut Hill MA, US
Aaron D. Gitler - Philadelphia PA, US
Anil Cashikar - Martinez GA, US
Antony A. Cooper - Sydney, AU
Cole M. Haynes - New York NY, US
Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA
The Curators of the University of Missouri - Columbia MO
International Classification:

C12N 1/16
US Classification:

4352542, 43525421, 435325, 435375
Abstract:

Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity.

Compounds, Compositions And Methods Of Inhibiting Alpha-Synuclein Toxicity
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US Patent:

8440705, May 14, 2013
Filed:

Sep 16, 2005
Appl. No.:

11/575481
Inventors:

Susan L. Lindquist - Chestnut Hill MA, US
Tiago Outeiro - Cambridge MA, US
Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA
FoldRx Pharmaceuticals, Inc. - Cambridge MA
International Classification:

C07D 277/82
A61K 31/428
US Classification:

514367, 548161
Abstract:

Compounds and compositions are provided for treatment or amelioration of one or more symptoms of α-synuclein toxicity, α-synuclein mediated diseases or diseases in which α-synuclein fibrils are a symptom or cause of the disease. In one embodiment, the compounds for use in the compositions and methods are heteroaryl acylguanidines, heteroarylhydrazones, dihydropyridones, heteroaryl and aryl styryl ketones, and heteroarylpyrazoles.

Modulators Of Alpha-Synuclein Toxicity
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US Patent:

8501465, Aug 6, 2013
Filed:

Dec 22, 2008
Appl. No.:

12/809859
Inventors:

Susan L. Lindquist - Chestnut Hill MA, US
Aaron D. Gitler - Philadelphia PA, US
Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:

C12N 15/63
C12N 15/85
C07H 21/04
US Classification:

4353201, 536 231, 435325
Abstract:

Disclosed are genes that, when overexpressed in cells expressing alpha-synuclein, either suppress or enhance alpha-synuclein mediated cellular toxicity. Compounds that modulate expression of these genes or activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to treat or prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity.

Mammalian Prion Proteins And Transgenic Mice Expressing Them
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US Patent:

20040048237, Mar 11, 2004
Filed:

May 15, 2003
Appl. No.:

10/438628
Inventors:

Susan Lindquist - Chestnut Hill MA, US
Jiyan Ma - Chicago IL, US
International Classification:

C12Q001/00
G01N033/53
G01N033/567
US Classification:

435/004000, 435/007200
Abstract:

The invention relates to methods of identifying, detecting or designing drugs that inhibit the formation of or accumulation of PrP, PrPor both in cells; to drugs that inhibit the formation of or accumulation of PrP, PrPor both in cells; to methods of preventing or reducing the adverse effects of PrP, PrPor both in humans; and to transgenic nonhuman mammals, such as transgenic mice, that ectopically express PrP.

Resumes

Susan Lindquist

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Location:

United States

Susan Lindquist

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Location:

United States

Project Director At Parexel

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Position:

Project Director at PAREXEL

Location:

Paradise Valley, Arizona

Industry:

Pharmaceuticals

Work:

PAREXEL since Nov 2010
Project Director
PAREXEL International Oct 2008 - Nov 2010
Senior Project Manager
PAREXEL International May 2006 - Oct 2008
Project Manager
PAREXEL International Dec 2004 - May 2006
Senior Clinical Research Associate/Clinical Lead
PAREXEL International Dec 2001 - Dec 2004
Clinical Research Associate II

Education:

San Diego State University-California State University 1998 - 2000
MPH, Epidemiology Baylor University 1994 - 1998
BA, Biology

Skills:

Clinical Trials
Oncology
Therapeutic Areas
Phase I
Vaccines
Gastroenterology
Rheumatoid Arthritis
Osteoporosis
EDC
Clinical Monitoring
CTMS
CRO

Susan Lindquist

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Location:

United States

Marketing And Advertising Professional

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Location:

Portland, Maine Area

Industry:

Marketing and Advertising

Education:

Penn State University

Amazon

Heat Shock

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During the last years the heat shock response has been stu- died as a model system to analyze control mechanisms regula- ting the synthesis of heat shock proteins providing impor- tant general insight into the regulation of gene expression. But the major revelation, which has sparked interest ...

Binding
Paperback

Pages
320

Publisher
Springer

ISBN #
3642766811

EAN Code
9783642766817

ISBN #
6

Summer Soldiers

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Reminiscent of Stand by Me and Lily's Crossing, this story of courage and camaraderie during World War I will touch the hearts of readers.Joe is trying hard to be brave. His father has left to fight in the Great War, and now it's up to him, at age 11, to keep his household and sheep ranch running sm...

Author
Susan Hart Lindquist

Binding
Paperback

Pages
192

Publisher
Yearling

ISBN #
0440415373

EAN Code
9780440415374

ISBN #
2

Wander

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He just appears one day--a grayish dog with white-tipped ears and a tail that wags like crazy. And he keeps coming back, until it feels to James and his younger sister, Sary, as if the old stray is their very own. Soon they've given the dog a name, and after that both children are bound to protect h...

Author
Susan Hart Lindquist

Binding
Paperback

Pages
133

Publisher
Yearling

ISBN #
0440414431

EAN Code
9780440414438

ISBN #
1

Walking the Rim

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When an earthquake separates Rudy from his parents during their annual family camping trip, the boy discovers a way of living unlike the way to which he has grown accustomed and takes his first steps toward adulthood.

Author
Susan Hart Lindquist

Binding
Library Binding

Pages
139

Publisher
Boyds Mills Pr

ISBN #
1563970988

EAN Code
9781563970986

ISBN #
8

Hund sucht Familienanschluss. ( Ab 10 J.).

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Author
Susan Hart Lindquist

Binding
Hardcover

Publisher
Ueberreuter

ISBN #
380002764X

EAN Code
9783800027644

ISBN #
7

Wander

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Author
Susan Hart Lindquist

Binding
Paperback

Publisher
Dell Publishing Co.. Inc.

ISBN #
4

Wikipedia

Susan Lindquist

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Susan Lindquist (born June 5, 1949) is a professor of biology at MIT specializing in molecular biology, particularly the protein folding problem within a family of...

ISBN #
3

Myspace

Susan Lindquist

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Locality:

Michigan

Gender:

Female

Birthday:

1948

Susan Lindquist

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Locality:

SMITHVILLE, MISSOURI

Gender:

Female

Birthday:

1934

susan Lindquist

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Locality:

HYRUM, Utah

Gender:

Female

Birthday:

1935

Classmates

Susan Bruno (Lindquist)

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Schools:

Levittown Memorial High School Levittown NY 1960-1964

Community:

Patrick Lyons

Biography:

Hi everyone! I'm still in Spring Hill, Florida on the West Coast, 1 hour north of T...

Susan Susan Leonard (Lin...

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Schools:

Hillis Elementary School Des Moines IA 1956-1958, Corinth Elementary School Shawnee Mission KS 1959-1962, Perkins Elementary School Des Moines IA 1963-1964, Franklin Junior High School Des Moines IA 1963-1966

Biography:

LifeI ended up in Kansas City-worked at AT&T for 20 yrs in sales & marketing-recent...

Susan Lindquist (Demars/m...

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Schools:

Buffalo High School Buffalo MN 1968-1972

Community:

Susan Mattson, Jane Lewis, Arquelio Hernandez

Susan Byram (Lindquist)

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Schools:

Mt. St. Benedict High School Crookston MN 1966-1970

Community:

Annette Landers, Scott Vansickel, Pat Sheldon, Alana Rainn

Susan Worchel (Lindquist)

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Schools:

St. Henry's School Bayonne NJ 1960-1964

Community:

Maureen Conlin, Toniann Mattaliano, Richard Prazych

Susan Edmonds (Lindquist)

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Schools:

Sacred Heart High School Memphis TN 1958-1962

Community:

Eula Dillashaw, Mary Arguelles, Karen Ranes

Susan Lindquist

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Schools:

Superior High School Superior WI 1965-1969

Susan Lindquist

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Schools:

St. Peter Canisius School Chicago IL 1957-1965

Community:

Paul Solak, Raquel Rhea, Marilyn Malecki, Katherine Dugo

Googleplus

Susan Lindquist

Education:

Park Hill 1994

Tagline:

My name is Susan Lindquist, I am a very proud wife and Mother. My Husband and I have been together 15 years and married 13 this April. Together we have 4 amazing children and.

Bragging Rights:

Have survived having teenagers. Now I understand why my mom was uptight.

Susan Lindquist

Mylife

Susan Lindquist

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Tags:

Female, Age: 54

Locality:

Hilliard, OH

susan lindquist

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Tags:

Female, Age: 46

Locality:

Reston, VA

Susan Lindquist (Lang)

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Tags:

Female, Age: 60, Principal

Locality:

Lake Mary, FL

Susan Lindquist

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Tags:

Female, Age: 62, Nurses

Locality:

Forest Lake, MN

SUSAN LINDQUIST

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Tags:

Age: 56

Locality:

Barrington, IL

Susan Lindquist

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Tags:

Female, Age: 37

Locality:

Meadville, PA

susan lindquist

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Tags:

Female, Age: 24, Principal

Locality:

Harper Woods, MI

Susan Lindquist (Tuttle)

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Tags:

Female, Age: 57

Locality:

Lihue, HI

News

Rapid Stem Cell Model Advances Parkinson’s Research

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elle T. Sagredo, Ludovica Zaccagnini, Meral Celikag, Jackson Sandoe, Nader Morshed, Toru Ichihashi, Theresa Bartels, Xin Jiang, Challana Tea, Zichen Wang, Hiroyuki Hakozaki, Thorold W. Theunissen, Haoyi Wang, Rudolf Jaenisch, Susan Lindquist, Beth Stevens, Nadia Stefanova, Gregor Wenning, Wilma D.J. v
Date: Jul 29, 2024
Category: Health
Source: Google

New biotech firm launched to find treatments for neurodegenerative diseases

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experts on such diseases. The team signifies a partnership between Susan Lindquist, winner of the National Medal of Science 2009 and member of the Whitehead Institute at the Massachusetts Institute of Technology, and Tony Coles, former CEO of San Francisco-based cancer drug maker Onyx Pharmaceuticals.
Date: Dec 16, 2014
Category: Health
Source: Google

After Spinning Onyx into Gold, Coles Returns to Lead a CNS Startup

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umanityand itschairman and CEO. He formed the company with scientific founder Susan Lindquist, with the goal of treating diseases caused by protein misfoldingwhen a mistake occurs in the complicated origami that turns a long linear chain of amino acids into a functional, three-dimensional protein. The
Date: Dec 15, 2014
Category: Health
Source: Google

Biotech Entrepreneur Tony Coles Takes Aim At Parkinson's And Alzheimer's

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The new startup, Yumanity, will be based in Cambridge, Mass., and is built around technologies developed by Susan Lindquist, the former director of the MIT-affiliated Whitehead Institute for Biomedical Research. Three researchers who worked in Lindquists lab will serve as founding scientists for th
Date: Dec 15, 2014
Category: Health
Source: Google

Former Onyx CEO Returns to Biotech to Launch Boston Start Up

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(Yes, Boston/Cambridge tops San Franciscoin biotech these days, no doubt.) Coles' founding partner in the new Yumanity venture is Susan Lindquist, an award-winning scientist from the Whitehead Institute at MIT. Lindquist is a pioneer in the field of protein misfolding, which is believed to play a
Date: Dec 15, 2014
Category: Health
Source: Google

New biotech startup Yumanity targets Alzheimer's, Parkinson's and ALS

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Yumanity signifies a partnership between Susan Lindquist, a2009winner of theNational Medal of Science andmember of the Whitehead Institute at the Massachusetts Institute of Technology,andTony Coles, who was most recently the chairman and CEO of the San Francisco-based cancer drug maker Onyx Ph
Date: Dec 15, 2014
Category: Health
Source: Google

Tony Coles' New Company, Yumanity, To Focus On New Parkinson's ...

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simple ones; they are not easy problems to solve. But if anyone can do it, is Tony Coles, and his new company, Yumanity. The Cambridge, Mass-based company is actually built around new technologies built by former director of the ITT-affiliated Whitehead Institute for Biomedical Research, Susan Lindquist.
Date: Dec 15, 2014
Category: Health
Source: Google

Research Explains How Cavefish Lost its Eyes for Environment Adaptation

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Biology professor and Whitehead Institute member Susan Lindquist said that these mutations are held in check by the heat-shock protein HSP90. Her research proved the HSP90s keeping genetic disparities from occurring in different types of organisms. Her studies show that during times of extreme anxi
Date: Dec 13, 2013
Category: Sci/Tech
Source: Google