Susan S Percival

US Patent:

20140134206, May 15, 2014

Filed:

Mar 30, 2012

Appl. No.:

14/008995

Inventors:

Christina Khoo - Lakeville-Middleboro MA, US
Deann Liska - Battle Creek MI, US
Susan S. Percival - Gainesville FL, US

Assignee:

UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. - Gainesville FL
OCEAN SPRAY CRANBERRIES, INC. - Lakeville-Middleboro MA

International Classification:

A61K 31/352
A61K 39/00
A61K 45/06

US Classification:

4242041, 514456, 549406, 4242341

Abstract:

Therapeutic use of extracts containing proanthocyanidin including treating disorders, e.g., inflammatory disorders, e.g., inflammatory bowel disease, Crohn's disease, ulcerative colitis, indeterminate colitis, microscopic colitis, collagenous colitis, and irritable bowel syndrome. Methods of increasing a subject's immunological resistance to an infection and/or treating the infection. The infection can be, e.g., a bacterial, viral, or fungal infection. The methods can include, e.g., selecting a subject that has, or is at risk of developing, an infection, e.g., a bacterial, viral, or fungal infection, or a combination thereof; providing a composition comprising at least about 10% proanthocyanidin by weight; and administering to the subj ect an amount of the composition to the subject, to thereby increase a subject's immunological resistance to an infection and/or to treat the infection.