Susan E Richards

US Patent:

20220187327, Jun 16, 2022

Filed:

Nov 23, 2021

Appl. No.:

17/534012

Inventors:

- Cambridge MA, US
Susan Richards - Bridgewater NJ, US
Valerie Theobald - Bridgewater NJ, US
Yuanxin Xu - Bridgewater NJ, US
Jad Zoghbi - Bridgewater NJ, US

International Classification:

G01N 33/94
G01N 33/53
G01N 33/539
G01N 33/68

Abstract:

Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.

US Patent:

20210008074, Jan 14, 2021

Filed:

Dec 21, 2018

Appl. No.:

16/955391

Inventors:

- Cambridge MA, US
Johnson TRAN - Bridgewater NJ, US
Susan M. RICHARDS - Bridgewater NJ, US

International Classification:

A61K 31/519
A61K 39/395
A61K 31/675
A61K 31/69
A61K 31/52
A61K 38/13
A61K 31/365
A61K 38/47
G01N 33/68
C12Q 1/6883
A61K 9/00
A61P 3/00

Abstract:

The present application provides methods of treating a disease, such as Pompe disease, in a subject, comprising detecting an erythropoiesis biomarker in a sample of the subject after administration of methotrexate and a therapeutic agent to the subject, and administering further treatment with or without concurrently administering additional immune tolerance induction or immunosuppression therapy based on the level of the erythropoiesis biomarker. Further provided by the present application are methods and kits for assessing the level of immune tolerance to a therapeutic agent in a subject based on detection of an erythropoiesis biomarker after administration of methotrexate and the therapeutic agent to the subject.

US Patent:

20180088140, Mar 29, 2018

Filed:

Aug 8, 2017

Appl. No.:

15/671663

Inventors:

- Cambridge MA, US
Susan Richards - Bridgewater NJ, US
Valerie Theobald - Bridgewater NJ, US
Yuanxin Xu - Bridgewater NJ, US
Jad Zoghbi - Bridgewater NJ, US

International Classification:

G01N 33/94
G01N 33/68
G01N 33/53
G01N 33/539

Abstract:

Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.

US Patent:

20150226758, Aug 13, 2015

Filed:

Feb 11, 2015

Appl. No.:

14/619422

Inventors:

- Cambridge MA, US
Susan Richards - Bridgewater NJ, US
Valerie Theobald - Bridgewater NJ, US
Yuanxin Xu - Bridgewater NJ, US
Jad Zoghbi - Bridgewater NJ, US

International Classification:

G01N 33/94
G01N 33/539
G01N 33/53

Abstract:

Methods and kits for detecting antibodies (e.g., anti-drug antibodies). Such methods and kits permit the detection of, for example, anti-drug antibodies in human body fluids, such as blood, plasma and serum.