Dr. Tam graduated from the Midwestern University/ Chicago College of Osteopathic Medicine in 1998. She works in Ferndale, MI and specializes in Family Medicine. Dr. Tam is affiliated with Providence Hospital and William Beaumont Hospital.
Us Patents
Anti-Il-6 Antibody Nucleic Acid Molecules And Methods
Yan Chen - Wayne PA, US Debra Gardner - Bear DE, US David M. Knight - Berwyn PA, US Michael W. Lark - Devon PA, US Bailin Liang - Gilbertsville PA, US David J. Shealy - Downingtown PA, US Xiao-Yu R. Song - West Chester PA, US Raymond W. Sweet - Bryn Mawr PA, US Susan H. Tam - Boothwyn PA, US Sheng-Jiun Wu - Broomall PA, US Jing Yang - Ambler PA, US David Matthew Marquis - Encinitas CA, US Eric Michael Smith - San Diego CA, US Alain Philippe Vasserot - Carlsbad CA, US
International Classification:
C12N 5/10 C12N 15/13 C12N 15/63
US Classification:
435 696, 536 2353, 4352523, 4353201, 435325
Abstract:
Anti-IL-6 antibody nucleic acids, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Methods Of Treating Conditions Using Anti-Il-6 Antibodies
Yan Chen - Wayne PA, US Debra Gardner - Bear DE, US David M. Knight - Berwyn PA, US Michael W. Lark - Devon PA, US Bailin Liang - Gilbertsville PA, US David J. Shealy - Downingtown PA, US Xiao-Yu R. Song - West Chester PA, US Raymond W. Sweet - Bryn Mawr PA, US Susan H. Tam - Boothwyn PA, US Sheng-Jiun Wu - Broomall PA, US Jing Yang - Ambler PA, US David Matthew Marquis - Encinitas CA, US Eric Michael Smith - San Diego CA, US Alain Philippe Vasserot - Carlsbad CA, US
Assignee:
Centocor, Inc. - Malvern PA Applied Molecular Evolution, Inc. - San Diego CA
International Classification:
A61K 39/395
US Classification:
4241451, 4241301, 4241411
Abstract:
Anti-IL-6 antibodies are used to treat IL-6 related conditions, such as rheumatoid arthritis, osteoarthritis, osteolysis, aseptic loosening of orthopedic implants, systemic lupus erythematosus, cutaneous lupus erythematosus, lupus nephritis, type 2 diabetes mellitus, chronic obstructive pulmonary disease, and renal cell carcinoma.
Anti-Il-6 Antibodies, Compositions, Methods And Uses
Yan Chen - Wayne PA, US Debra Gardner - Bear DE, US David M. Knight - Berwyn PA, US Michael W. Lark - Devon PA, US Bailin Liang - Gilbertsville PA, US David J. Shealy - Downingtown PA, US Xiao-Yu R. Song - West Chester PA, US Raymond W. Sweet - Bryn Mawr PA, US Susan H. Tam - Boothwyn PA, US Sheng-Jiun Wu - Broomall PA, US Jing Yang - Ambler PA, US David Matthew Marquis - Encinitas CA, US Eric Michael Smith - San Diego CA, US Alain Philippe Vasserot - Carlsbad CA, US
Assignee:
Janssen Biotech, Inc. - Horsham PA Applied Molecular Evolution - San Diego CA
International Classification:
A61M 37/00 A61M 5/32 A61K 39/395 C07K 16/24
US Classification:
604143, 604198, 4241391, 53038823
Abstract:
An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Anti-Il-6 Antibodies, Compositions, Methods And Uses
Yan Chan - Radnor PA, US Debra Gardner - Radnor PA, US David M. Knight - Berwyn PA, US Michael W. Lark - Berwyn PA, US Bailin Liang - Jacksonville FL, US David J. Shealy - Radnor PA, US Xiao-yu R. Song - Somerville NJ, US Raymond W. Sweet - Radnor PA, US Susan H. Tam - Radnor PA, US Sheng-Jiun Wu - Radnor PA, US Jing Yang - Ambler PA, US David Matthew Marquis - Encinitas CA, US Eric Michael Smith - San Diego CA, US Alain Philippe Vasserot - Carlsbad CA, US
Assignee:
Janssen Biotech, Inc. - Horsham PA Applied Molecular Evolution - San Diego CA
International Classification:
A61K 39/395 C07K 16/24 C12N 5/12
US Classification:
4241391, 53038823, 435326
Abstract:
An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Yan Chen - Wayne PA, US Debra Gardner - Bear DE, US David M. Knight - Berwyn PA, US Michael W. Lark - Devon PA, US Bailin Liang - Gilbertsville PA, US David J. Shealy - Downingtown PA, US Xiao-Yu R. Song - West Chester PA, US Raymond W. Sweet - Bryn Mawr PA, US Susan H. Tam - Boothwyn PA, US Sheng-Jiun Wu - Broomall PA, US Jing Yang - Ambler PA, US David Matthew Marquis - Encinitas CA, US Eric Michael Smith - San Diego CA, US Alain Philippe Vasserot - Carlsbad CA, US
Assignee:
Janssen Biotech, Inc. - Horsham PA Applied Molecular Evolution - San Diego CA
International Classification:
A61K 39/395
US Classification:
4241391, 4241411
Abstract:
An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Method Of Promoting Graft Survival With Anti-Tissue Factor Antibodies
Robert Jordan - Thornton PA, US Susan Tam - Boothwyn PA, US Janet Davis - Branchburg NJ, US Mark Zimmerman - East Brunswick NJ, US Gang Xu - Belle Meade NJ, US Norma Kenyon - Miami FL, US
International Classification:
A61K039/395
US Classification:
424145100
Abstract:
The present invention is directed to a method of using function blocking tissue factor antibodies to enhance graft survival in mammals. Function blocking antibodies having the effect of blocking activated tissue factor (TF), TF and its ligand FVII as either the inactive TF:FVII or active TF:FVIIa complex, or block the formation of the TF:FVIIa:FX ternary complex are useful in the method. These properties provide a therapy that has directed action towards thrombotic events involving tissue-plasma interactions but does not prevent the intrinsic pathway for coagulation. Activated TF arises on cells, tissues, and organs during or after transplantation and is a major cause of graft loss.
Anti-Il-6 Antibodies, Compositions, Methods And Uses
Yan Chen - Wayne PA, US Debra Gardner - Bear DE, US David Knight - Berwyn PA, US Michael Lark - Devon PA, US Bailin Liang - Gilbertsville PA, US David Shealy - Downingtown PA, US Xiao-Yu Song - West Chester PA, US Raymond Sweet - Bryn Mawr PA, US Susan Tam - Boothwyn PA, US Sheng-Jiun Wu - Broomall PA, US Jing Yang - Ambler PA, US David Marquis - Encinitas CA, US Eric Smith - San Diego CA, US Alain Vasserot - Carlsbad CA, US
International Classification:
A61K 39/395 C07H 21/04 C07K 16/24
US Classification:
424145100, 530388230, 536023530
Abstract:
An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Agents That Interfere With Il-1Beta Receptor Signalling
- Hong Kong, CN Susan TAM - Garnet Valley PA, US Minseon CHO - Breinigsville PA, US Lihua SHI - Wynnewood PA, US
Assignee:
TAVOTEK BIOTHERAPEUTICS (HONG KONG) LIMITED - Hong Kong
International Classification:
C07K 16/24 A61P 19/02
Abstract:
The present disclosure relates to antibodies that specifically bind and neutralize interleukin-1β (IL-1β), and to the use of such antibodies for the therapeutic treatment of IL-1β-mediated diseases and disorders.