Suzanne G Maher

US Patent:

20090017096, Jan 15, 2009

Filed:

Aug 15, 2006

Appl. No.:

11/997453

Inventors:

Anthony Lowman - Wallingford PA, US
Suzanne A. Maher - New York NY, US
Lorenzo Pio Serino - Reggello, IT
Kara Spiller - Philadelphia PA, US
Peter A. Torzilli - Ridgefield CT, US

International Classification:

A61L 27/58

US Classification:

424426

Abstract:

A non-biodegradable hydrogel matrix containing microspheres of a biodegradable polymer for the purpose of treating, repairing, or replacing damaged biological tissue is described. The biodegradable phase can be admixed with a chemoattractant. Examples of degradable polymers include degradable polyesters such as 50:50 PLA:PGA, the degradation profiles of which are well characterized. The matrix is permanently inserted into a tissue defect to provide mechanical support before, during, and after tissue ingrowth.

US Patent:

20110288199, Nov 24, 2011

Filed:

May 19, 2010

Appl. No.:

12/783393

Inventors:

Anthony M. Lowman - Wallingford PA, US
Giuseppe R. Palmese - Hainesport NJ, US
Suzanne A. Maher - New York NY, US
Russell F. Warren - Greenwich CT, US
Timothy M. Wright - New York NY, US
Julianne L. Holloway - Philadelphia PA, US

International Classification:

A61L 27/48
A61F 2/44
A61F 2/38
A61F 2/08
A61F 2/02
A61F 2/28

US Classification:

523114, 523113, 523115

Abstract:

The present invention includes tailored fiber-reinforced hydrogel composites for implantation into a subject. The present invention also includes systems and methods for controlling the relative percent volume of the hydrogel and fibers, cross-linking, fiber orientation, weave and density, such that the material properties of the composite can be controlled and/or customized to match particular tissue types. The composites of the present invention are suitable for repairing or replacing musculoskeletal tissues and/or fibrocartilage, such as the meniscus, ligaments and tendons.