Teresa L Gilbert

US Patent:

6495668, Dec 17, 2002

Filed:

May 3, 2000

Appl. No.:

09/564595

Inventors:

Teresa Gilbert - Seattle WA
Charles E. Hart - Woodinville WA
Paul O. Sheppard - Granite Falls WA
Debra G. Gilbertson - Seattle WA

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

A61K 3824

US Classification:

530399, 435 694, 435 701, 530350, 536 234

Abstract:

Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.

US Patent:

6927040, Aug 9, 2005

Filed:

Jun 29, 2001

Appl. No.:

09/895834

Inventors:

Paul O. Sheppard - Granite Falls WA, US
Scott R. Presnell - Tacoma WA, US
Brian A. Fox - Seattle WA, US
Teresa Gilbert - Seattle WA, US
Betty A. Haldeman - Seattle WA, US
Francis J. Grant - Seattle WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

C12P021/06
C12N015/21
C07H021/04

US Classification:

435 691, 435695, 435 6951, 435 701, 4353201, 435325, 536 235, 536 2352, 536 241

Abstract:

The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-α at the amino acid sequence level. The present invention also includes antibodies to the Zcyto21 polypeptides, and methods of using the polynucleotides and polypeptides.

US Patent:

6962802, Nov 8, 2005

Filed:

Jun 6, 2001

Appl. No.:

09/876813

Inventors:

Teresa Gilbert - Seattle WA, US
Charles E. Hart - Woodinville WA, US
Paul O. Sheppard - Granite Falls WA, US
Debra G. Gilbertson - Seattle WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

C12N015/09
C12N015/00
C07H021/04
A61K038/24
A61K038/27

US Classification:

435 694, 435 691, 4353201, 530350, 530399, 536 2351, 536 231, 536 235

Abstract:

Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 70% identical to residues 52-179 of SEQ ID NO:2 or residues 258-370 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.

US Patent:

7241870, Jul 10, 2007

Filed:

Aug 27, 2004

Appl. No.:

10/928539

Inventors:

Paul O. Sheppard - Granite Falls WA, US
Scott R. Presnell - Tacoma WA, US
Brian A. Fox - Seattle WA, US
Teresa Gilbert - Seattle WA, US
Betty A. Haldeman - Seattle WA, US
Francis J. Grant - Seattle WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

C07K 14/52
C12N 15/20
C12P 21/00
A61K 38/00

US Classification:

530351, 435 6951, 435 701, 435325, 424 854

Abstract:

The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-α at the amino acid sequence level. The present invention also includes antibodies to the Zcyto21 polypeptides, and methods of using the polynucleotides and polypeptides.

US Patent:

7252969, Aug 7, 2007

Filed:

Aug 27, 2004

Appl. No.:

10/927891

Inventors:

Paul O. Sheppard - Granite Falls WA, US
Scott R. Presnell - Tacoma WA, US
Brian A. Fox - Seattle WA, US
Teresa Gilbert - Seattle WA, US
Betty A. Haldeman - Seattle WA, US
Francis J. Grant - Seattle WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

C12N 15/00
C12N 15/21
C07H 21/04
A61K 38/00
C12P 21/00

US Classification:

435 691, 435 6951, 435325, 435 701, 4353201, 536 2352, 536 241, 424 854

Abstract:

The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-α at the amino acid sequence level. The present invention also includes antibodies to the Zcyto21 polypeptides, and methods of using the polynucleotides and polypeptides.

US Patent:

7253261, Aug 7, 2007

Filed:

Aug 27, 2004

Appl. No.:

10/927815

Inventors:

Paul O. Sheppard - Granite Falls WA, US
Scott R. Presnell - Tacoma WA, US
Brian A. Fox - Seattle WA, US
Teresa Gilbert - Seattle WA, US
Betty A. Haldeman - Seattle WA, US
Francis J. Grant - Seattle WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

C07K 14/52
C12N 15/20
C12P 21/00

US Classification:

530351, 435 6951, 435 701, 435325, 424 854

Abstract:

The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-α at the amino acid sequence level. The present invention also includes antibodies to the Zcyto21 polypeptides, and methods of using the polynucleotides and polypeptides.

US Patent:

7323446, Jan 29, 2008

Filed:

Oct 17, 2006

Appl. No.:

11/550246

Inventors:

Teresa Gilbert - Seattle WA, US
Charles E. Hart - Woodinville WA, US
Paul O. Sheppard - Granite Falls WA, US
Debra G. Gilbertson - Seattle WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

A61K 38/00
A61K 38/24
C07K 1/00
C12N 15/09
C12P 21/04

US Classification:

514 12, 530399, 530350, 435 694, 435 701, 435 691, 4241921, 4241981

Abstract:

Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 70% identical to residues 52-179 of SEQ ID NO:2 or residues 258-370 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.

US Patent:

7375182, May 20, 2008

Filed:

Mar 15, 2005

Appl. No.:

11/080803

Inventors:

Teresa Gilbert - Seattle WA, US
Charles E. Hart - Woodinville WA, US
Paul O. Sheppard - Granite Falls WA, US

Assignee:

ZymoGenetics, Inc. - Seattle WA

International Classification:

A61K 38/00
A61K 38/24
C12P 21/06
C07H 21/04

US Classification:

530324, 530399, 435 691, 536 235

Abstract:

Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that is at least 70% identical to residues 52-179 of SEQ ID NO:2 or residues 258-370 of SEQ ID NO:2. Multimers of the polypeptides are also disclosed. The polypeptides, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents.