Thao M Tran

US Patent:

6656500, Dec 2, 2003

Filed:

Jan 12, 2001

Appl. No.:

09/760133

Inventors:

Bruce A. Firestone - Irvine CA
Thao T. Tran - Garden Grove CA

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 948

US Classification:

424451, 424452, 424455, 514432, 514725

Abstract:

A capsule system for oral delivery of an active agent having low aqueous solubility generally includes, in combination with the active agent, a vehicle for preventing initial active agent dissolution within the gastrointestinal tract and an emulsifier for promoting self-emulsification of the active agent and vehicle in the gastrointestinal tract. A capsule shell is provided for encapsulating the active agent, vehicle and emulsifier with the shell being formulated to open upon ingestion into the gastrointestinal tract and release the active agent and vehicle.

US Patent:

7115277, Oct 3, 2006

Filed:

Dec 2, 2002

Appl. No.:

10/308295

Inventors:

Bruce A. Firestone - Irvine CA, US
Thao Tran - Fountain Valley CA, US
Teresa G. Joshi - Irvine CA, US

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 9/48
A61K 9/66

US Classification:

424451, 424452, 424455, 514432, 705 2

Abstract:

A method for enabling deliver of an active agent is provided which includes the preparation of doses of the active agent distributing educational materials and guidelines for counseling patients with regard to what the patients need to know and what the patients must do in order to both avoid adverse side effects while taking the dose and to receive prescriptions for the doses.

US Patent:

20040115257, Jun 17, 2004

Filed:

Nov 21, 2003

Appl. No.:

10/719287

Inventors:

Bruce Firestone - Irvine CA, US
Thao Tran - Garden Grove CA, US

International Classification:

A61K009/48
A61K031/07
A61K031/203

US Classification:

424/452000, 514/559000, 514/725000

Abstract:

A capsule system for oral delivery of an active agent having low aqueous solubility generally includes, in combination with the active agent, a vehicle for preventing initial active agent dissolution within the gastrointestinal tract and an emulsifier for promoting self-emulsification of the active agent and vehicle in the gastrointestinal tract. A capsule shell is provided for encapsulating the active agent, vehicle and emulsifier with the shell being formulated to open upon ingestion into the gastrointestinal tract and release the active agent and vehicle.

US Patent:

55854060, Dec 17, 1996

Filed:

Jun 9, 1993

Appl. No.:

8/074318

Inventors:

Shulin Ding - Irvine CA
Thao T. Tran - Garden Grove CA

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 4700

US Classification:

514772

Abstract:

A nonirritating, nonionic detergent surfactant composition suitable for application to and cleaning of sensitive tissue, including periocular and ocular tissue, having a low cytotoxicity and high cleaning ability includes a principal nonionic surfactant and at least one auxiliary nonionic surfactant present in the surfactant composition in sufficient amounts to increase the cleaning ability of the principal non-ionic surfactant.

US Patent:

62483544, Jun 19, 2001

Filed:

Mar 4, 1999

Appl. No.:

9/262623

Inventors:

Bruce A. Firestone - Irvine CA
Thao T. Tran - Garden Grove CA

Assignee:

Allergan Sales, Inc. - Irvine CA

International Classification:

A61K 948
A61K 3107
A61K 3138

US Classification:

424451

Abstract:

A capsule system for oral delivery of an active agent having low aqueous solubility generally includes, in combination with the active agent, a vehicle for preventing initial active agent dissolution within the gastrointestinal tract and an emulsifier for promoting self-emulsification of the active agent and vehicle in the gastrointestinal tract. A capsule shell is provided for encapsulating the active agent, vehicle and emulsifier with the shell being formulated to open upon ingestion into the gastrointestinal tract and release the active agent and vehicle.

US Patent:

52522466, Oct 12, 1993

Filed:

Jan 10, 1992

Appl. No.:

7/819397

Inventors:

Shulin Ding - Irvine CA
Thao T. Tran - Garden Grove CA

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

C11D 166

US Classification:

25217421

Abstract:

A nonirritating, nonionic detergent surfactant composition suitable for application to and cleaning of sensitive tissue, including periocular and ocular tissue, having a low cytotoxicity and high cleaning ability includes a principal nonionic surfactant and at least one auxiliary nonionic surfactant present in the surfactant composition in sufficient amounts to increase the cleaning ability of the principal non-ionic surfactant.

US Patent:

55187188, May 21, 1996

Filed:

Apr 28, 1994

Appl. No.:

8/234318

Inventors:

Shulin Ding - Irvine CA
Thao T. Tran - Garden Grove CA

Assignee:

Allergan, Inc. - Irvine CA

International Classification:

A61K 3174

US Classification:

424 7804

Abstract:

A nonirritating, nonionic detergent surfactant composition suitable for application to and cleaning of sensitive tissue, including periocular and ocular tissue, having a low cytotoxicity and high cleaning ability includes a principal nonionic surfactant and at least one auxiliary nonionic surfactant present in the surfactant composition in sufficient amounts to increase the cleaning ability of the principal nonionic surfactant.