Thomas James Bailey

US Patent:

42308640, Oct 28, 1980

Filed:

Jan 29, 1979

Appl. No.:

6/007518

Inventors:

Thomas D. Bailey - Indianapolis IN

Assignee:

Reilly Tar & Chemical Corp. - Indianapolis IN

International Classification:

C07D21304

US Classification:

546303

Abstract:

The chemical compound 5-trifluoromethyl-2-pyrone and a process for preparing a 5-trifluoromethyl-2-oxy compound of the formula ##STR1## wherein A is oxygen or nitrogen bearing a hydrogen, comprising the step of reacting an amount of the 5-carboxy precursor of the compound with a suitable fluorinating agent to selectively transform the 5-carboxy group without altering the oxygen function in the 2-position of the ring.

US Patent:

42490090, Feb 3, 1981

Filed:

Jan 29, 1979

Appl. No.:

6/007632

Inventors:

Thomas D. Bailey - Indianapolis IN

Assignee:

Reilly Tar & Chemical Corp. - Indianapolis IN

International Classification:

C07D21326

US Classification:

546345

Abstract:

One process comprises the step of reacting an amount of 5-carboxy-2-pyridone directly with both a suitable chlorinating agent and a suitable fluorinating agent to selectively transform both the 5-carboxy group and the 2-positioned oxygen function of the ring. A second process comprises the steps of reacting an amount of 5-carboxy-2-pyridone with a suitable fluorinating agent to selectively transform the 5-carboxy group without altering the 2-positioned oxygen function of the ring and reacting the 5-trifluoromethyl-2-pyridone thereby formed with a suitable chlorinating agent to cause 2-chloro-5-trifluoromethylpyridine to form. A third process comprises the steps of reacting an amount of a 5-carboxy-2-pyrone compound with a suitable fluorinating agent to selectively transform the 5-carboxy group without altering the 2-positioned oxygen function of the ring, reacting the 5-trifluoromethyl-2-pyrone compound thereby formed with an ammonia-containing agent in the presence of a caustic material to cause 5-trifluoromethyl-2-pyridone to form, and reacting the 5-trifluoromethyl-2-pyridone thereby formed with a suitable chlorinating agent to cause 2-chloro-5-trifluoromethylpyridine to form.

US Patent:

44057903, Sep 20, 1983

Filed:

Apr 8, 1982

Appl. No.:

6/366599

Inventors:

Charles K. McGill - Indianapolis IN
Thomas D. Bailey - Indianapolis IN

Assignee:

Reilly Tar & Chemical Corp. - Indianapolis IN

International Classification:

C07D21374

US Classification:

546304

Abstract:

An improved process for preparing the 2-alkylamino-5-alkylpyridine and 2-amino-5-alkylpyridine amination products of 3-alkylpyridines, comprising the step of initially reacting the base directly with the sodium salt of a primary alkylamine to produce the 2-alkylamino form, wherein the alkyl group in each reactant has from 1 to about 20 carbon atoms. The sodium salt is preferably preformed in situ by adding the alkylamine to a dispersion of sodium in an organic solvent heated to about 100. degree. -120. degree. C. The substituted amination preferably proceeds at a temperature of about 100. degree. -140. degree. C. in a solvent such as toluene and under an inert nitrogen atmosphere. The ratio of 2,5-:2,3- isomer products of the reaction is up to about 10:1 or more, with the effective yield of the 2,5-alkylated isomer being about 25% or more. This recovered 2-alkylamino-5-alkylpyridine product is readily dealkylated by reaction with hydrobromic or hydriodic acid with or without the presence of a pyridine hydrohalide salt to obtain the 2-amino-5-alkylpyridine product which has proven uses in herbicidal, insecticidal and pharmaceutical applications.

US Patent:

55741800, Nov 12, 1996

Filed:

Aug 1, 1994

Appl. No.:

8/284826

Inventors:

Donald McQuigg - Mooresville IN
Charles Marston - Midland MI
Gina Fitzpatrick - Indianapolis IN
Ernest Crowe - Beech Grove IN
Susan Vorhies - Indianapolis IN
Ramiah Murugan - Indianapolis IN
Thomas D. Bailey - Greenwood IN

Assignee:

Reilly Industries, Inc. - Indianapolis IN

International Classification:

C07C 5142
C07C 5948
C07C 3516
C07C 6510

US Classification:

558147

Abstract:

Described is a process for recovering phytic acid or phytic acid salt from a medium in which it is contained. This process includes contacting the medium with a solid-phase free base polymer having tertiary amine functions to adsorb the phytic acid or salt thereof. In one preferred mode, the medium to be treated also contains lactic acid, and separate fractions predominant in (i) lactic acid and (ii) phytic acid or phytic acid salt, respectively, are recovered. Also described are preferred processes for treating mediums to recover lactic acid therefrom, and a favored process for obtaining inositol directly by hydrolyzing phytic acid or phytic acid salt while adsorbed on a pyridine-containing polymer.

US Patent:

47539119, Jun 28, 1988

Filed:

Nov 24, 1986

Appl. No.:

6/934014

Inventors:

Gerald L. Goe - Greenwood IN
Thomas D. Bailey - Greenwood IN
James R. Beadle - Plainfield IN

Assignee:

Reilly Tar and Chemical Corp. - Indianapolis IN

International Classification:

B01J 3104
B01J 3106

US Classification:

502159

Abstract:

Insoluble complex oxidation catalysts comprising chromium salts bound on an insoluble polymer supports having pendant pyridine groups, that are useful in oxidation reactions such as Tetralino. RTM. to. alpha. -tetralone, ethylbenzene to acetophenone, and 2-methyl-5-ethylpyridine to 2-methyl-5-acetylpyridine. Also disclosed are processes for accomplishing such oxidations utilizing such catalysts.

US Patent:

41580931, Jun 12, 1979

Filed:

Dec 15, 1977

Appl. No.:

5/860787

Inventors:

Thomas D. Bailey - Indianapolis IN
Charles K. McGill - Indianapolis IN

Assignee:

Reilly Tar & Chemical Corporation - Indianapolis IN

International Classification:

C07D21306
C07D21322
C07D40302

US Classification:

542455

Abstract:

A process for dequaternizing a 2-(2-pyridyl)ethyl or 2-(4-pyridyl)ethyl quaternary salt of a pyridine or bipyridine base comprising the step of heating or reacting the pyridylethyl quaternary salt with a caustic material such as sodium hydroxide. Also included is a process for preparing a second pyridine base (or a bipyridine base) in which a first pyridine base is initially selected and its 2-(2-pyridyl)ethyl or 2-(4-pyridyl)ethyl quaternary salt or its acid salt prepared. An electrophilic, nucleophilic or coupling reaction can then be performed on the quaternary salt to change the substituent or to form the bipyridyl coupling and the resultant salt dequaternized with a caustic material, such as sodium hydroxide, to produce a second pyridine or a bipyridine base.

US Patent:

48393231, Jun 13, 1989

Filed:

Nov 2, 1987

Appl. No.:

7/115962

Inventors:

Gerald L. Goe - Greenwood IN
Thomas D. Bailey - Greenwood IN
James R. Beadle - Plainfield IN

Assignee:

Reilly Tar & Chemical Corporation - Indianapolis IN

International Classification:

B01J 3100
C07C 4500

US Classification:

502159

Abstract:

Insoluble complex oxidation catalysts comprising chromium salts bound on an insoluble polymer supports having pendant pyridine groups, that are useful in oxidation reactions such as Tetralin. RTM. to. alpha. -tetralone, ethylbenzene to acetophenone, and 2-methyl-5-ethylpyridine to 2-methyl-5-acetylpyridine. Also disclosed are processes for accomplishing such oxidations utilizing such catalysts.