Thomas Wilson Cullen

US Patent:

7300946, Nov 27, 2007

Filed:

Dec 8, 2003

Appl. No.:

10/538998

Inventors:

Ping Ding - Lawrenceville NJ, US
Daniel H. Cohen - Princeton NJ, US
John W. Lyga - Basking Ridge NJ, US
David S. Rosen - Kendall Park NJ, US
George Theodoridis - Princeton NJ, US
Qun Zhang - Princeton NJ, US
Walter H. Yeager - Yardley PA, US
Stephen F. Donovan - Revere PA, US
Steven Shunxiang Zhang - Plainsboro NJ, US
Inna Shulman - Langhorne PA, US
Seong Jae Yu - Pennington NJ, US
Guozhi Wang - Freshmeadow NJ, US
Y. Larry Zhang - Kendall Park NJ, US
Ariamala Gopalsamy - Mahwah NJ, US
Dennis L. Warkentin - East Windsor NJ, US
Paul E. Rensner - Yardley PA, US
Ian R. Silverman - Morrestown NJ, US
Thomas G. Cullen - Milltown NJ, US

Assignee:

Bayer CropScience AG - Monheim

International Classification:

A61K 31/44
A61K 31/445
A61K 31/4422
C07D 211/06
C07D 211/08
C07D 211/70
C07D 211/82

US Classification:

514317, 514331, 546229, 546237

Abstract:

It has now been found that certain novel N-(substituted aryl)-4(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is C or CH; and B, D, E, R, R, R, R, R, R, R, Rand Rare fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.

US Patent:

7365082, Apr 29, 2008

Filed:

Dec 8, 2003

Appl. No.:

10/538997

Inventors:

Ping Ding - Lawrenceville NJ, US
Daniel H. Cohen - Princeton NJ, US
John W. Lyga - Basking Ridge NJ, US
David S. Rosen - Kendall Park NJ, US
George Theodoridis - Princeton NJ, US
Qun Zhang - Princeton NJ, US
Walter H. Yeager - Yardley PA, US
Stephen F. Donovan - Revere PA, US
Steven Shunxiang Zhang - Plainsboro NJ, US
Inna Shulman - Langhorne PA, US
Seong Jae Yu - Pennington NJ, US
Guozhi Wang - Freshmeadow NJ, US
Y. Larry Zhang - Kendall Park NJ, US
Ariamala Gopalsamy - Mahwah NJ, US
Dennis L. Warkentin - East Windsor NJ, US
Paul E. Rensner - Yardley PA, US
Ian R. Silverman - Moorestown NJ, US
Thomas G. Cullen - Milltown NJ, US

Assignee:

Bayer CropScience AG - Monheim

International Classification:

A61K 31/44
A61K 31/445
A61K 31/4422
C07D 211/06
C07D 211/08
C07D 211/70
C07D 211/82

US Classification:

514317, 514331, 546229, 546237

Abstract:

It has now been found that certain novel N-(substituted aryl)-4-(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is CH or N; and B, D, E, R, R, R, R, R, R, R, Rand Rare fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.

US Patent:

7683070, Mar 23, 2010

Filed:

Oct 17, 2007

Appl. No.:

11/874015

Inventors:

Ping Ding - Lawrenceville NJ, US
Daniel H. Cohen - Princeton NJ, US
John W. Lyga - Basking Ridge NJ, US
David S. Rosen - Kendall Park NJ, US
George Theodoridis - Princeton NJ, US
Qun Zhang - Princeton NJ, US
Walter H. Yeager - Yardley PA, US
Stephen F. Donovan - Revere PA, US
Stephen Shunxiang Zhang - Plainsboro NJ, US
Inna Shulman - Langhorne PA, US
Seong Jae Yu - Pennington NJ, US
Guozhi Wang - Freshmeadow NJ, US
Y. Larry Zhang - Kendall Park NJ, US
Ariamala Gopalsamy - Mahwah NJ, US
Dennis L. Warkentin - East Windsor NJ, US
Paul E. Rensner - Yardley PA, US
Ian R. Silverman - Moorestown NJ, US
Thomas G. Cullen - Milltown NJ, US

Assignee:

FMC Corporation - Philadelphia PA

International Classification:

A61K 31/4523
A61K 31/4545
C07D 211/06
C07D 239/02

US Classification:

514256, 514315, 514269, 544298, 546184, 546192

Abstract:

It has now been found that certain novel N-(substituted aryl)-4-(disubstituted methyl)piperidine and pyridine derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I): wherein m, n, q, r, and s are independently selected from 0 or 1; and p is 0, 1, 2, or 3; A is C or CH; and B, D, E, R, R, R, R, R, R, R, Rand Rare fully described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.

US Patent:

50812874, Jan 14, 1992

Filed:

Jun 30, 1989

Appl. No.:

7/373423

Inventors:

Clinton J. Peake - Trenton NJ
Thomas G. Cullen - Milltown NJ
Anthony J. Martinez - Hamilton Square NJ

Assignee:

FMC Corporation - Philadelphia PA

International Classification:

C07C 6952
C07C 6973

US Classification:

560219

Abstract:

The present invention discloses and exemplifies alcohol, ether and ester derivatives of difluoroalkanes and difluoroalkenylalkanes having the general formula R--(CH. sub. 2). sub. m --CR. sup. 2 R. sup. 3 --OR. sup. 1, in which R is a 1,1-difluoroalkyl or a 1,1-difluoroalkenyl group, composition thereof, and use thereof to control agricultural crop pests.

US Patent:

48087629, Feb 28, 1989

Filed:

Sep 9, 1987

Appl. No.:

7/094617

Inventors:

Gary A. Meier - Robbinsville NJ
Scott M. Sieburth - Princeton NJ
Thomas G. Cullen - Milltown NJ
John F. Engel - Washington Crossing PA

Assignee:

FMC Corporation - Philadelphia PA

International Classification:

A01N 4340
C07D40912

US Classification:

514336

Abstract:

Compounds of the formula ##STR1## in which Ar is substituted or unsubstituted phenyl, naphthyl, or thienyl; Z is oxygen, sulfur, or methylene; and Ar' is 2-methyl[1,1'-biphenyl]-3-yl, 3-phenoxyphenyl, 4-fluoro-3-phenoxyphenyl, or 6-phenoxy-2-pyridyl exhibit pyrethroid-like insecticidal and acaricidal activity and are relatively harmless to aquatic fauna.

US Patent:

H19968, Oct 2, 2001

Filed:

Nov 20, 1998

Appl. No.:

9/196880

Inventors:

Clinton J. Peake - Trenton NJ
Thomas G. Cullen - Milltown NJ
Robert N. Henrie - Pennington NJ
Jane A. Dybas - Flemington NJ

Assignee:

FMC Corporation - Philadelphia PA

International Classification:

C07D42100
C07D21108
C07D21168
C07D40100

US Classification:

546199

Abstract:

It has now been found that certain novel photostable agriculturally acceptable organic or inorganic salts of formula I are useful as insecticides: ##STR1## where R is alkoxycarbonyl, alkoxycarbonylamino, cycloalkylalkoxy, 2-alkyl-2H-tetrazol-5-yl, or 2-haloalkyl-2H-tetrazol-5-yl; R. sup. 1 is trihaloalkyl, or trihaloalkoxy; n is 0, or 1; and, wherein said salts are derived from hydrochloric acid; hydrobromic acid; boric acid; phosphoric acid; maleic acid; fumaric acid; phthalic acid; salicylic acid optionally substituted with alkyl or halogen; D-glucuronic acid; the sulfonic acid R. sup. 2 SO. sub. 3 H where R. sup. 2 is alkyl, haloalkyl, hydroxyalkyl, D-10-camphoryl, or phenyl optionally substituted with alkyl or halogen; the carboxylic acid R. sup. 3 CO. sub. 2 H where R. sup. 3 is hydrogen, alkyl, trihaloalkyl, carboxyl, phenyl optionally substituted with alkyl or halogen, or pyridyl; the boronic acid R. sup. 4 B(OH). sub. 2 where R. sup.

US Patent:

49506668, Aug 21, 1990

Filed:

Mar 30, 1989

Appl. No.:

7/331563

Inventors:

Clinton J. Peake - Trenton NJ
Thomas G. Cullen - Milltown NJ
Anthony J. Martinez - Hamilton Square NJ

Assignee:

FMC Corporation - Philadelphia PA

International Classification:

A01N 3702
A01N 3718
C07C 6963
C07C103127

US Classification:

5142275

Abstract:

The present invention discloses compounds of the formula ##STR1## in which R is a 1,1-difluoroalkyl group or a 1,1-difluoroethenyl group having an even numbered carbon chain length of from 4 to 22 carbon atoms, pesticidal compositions thereof; and their use to control plant pests such as insects, acarids, and nematodes.

US Patent:

59394382, Aug 17, 1999

Filed:

Sep 9, 1998

Appl. No.:

9/150424

Inventors:

Walter H. Yeager - Yardley PA
Ian R. Silverman - Moorestown NJ
Robert N. Henrie - East Windsor NJ
Thomas G. Cullen - Milltown NJ
Clinton J. Peake - Trenton NJ

Assignee:

FMC Corporation

International Classification:

A01N 4340
C07D21126
C07D21128
C07D21118

US Classification:

514331

Abstract:

It has now been found that certain novel oximino and hydrazono derivatives of N-benzyl-4-benzhydryl- and 4-benhydrolpiperidines, and their corresponding N-oxides and agriculturally acceptable salts are useful as insecticides. These compounds are represented by Formula I: where R is hydrogen, halogen, alkyl, alkoxy, dialkylamino; R. sup. 1 is hydrogen, alkyl, haloalkyl, alkoxyalkyl, alkylcarbonyl and alkylaminocarbonyl; X is oxygen, or NR. sup. 2, Q is fluoro and hydroxy; Z is halogen, haloalkyl, haloalkoxy, pentahalothio, haloalkylthio, haloalkylsulfinyl, haloalkylsulfonyl, and --OCF. sub. 2 O-- attached to two adjacent carbon atoms of the phenyl ring; n is 0 or 1; and, when X is NR. sup. 2, R. sup. 2 is hydrogen, alkyl, alkylcarbonyl, alkoxycarbonyl, or R. sup. 1 and R. sup. 2 taken together may be --C. sub. m H. sub. 2. spsb. m, or --C. sub. 2 H. sub. 4 OC. sub. 2 H. sub.