Thomas R Matthews

US Patent:

46598766, Apr 21, 1987

Filed:

Aug 30, 1983

Appl. No.:

6/527797

Inventors:

Thomas M. Sullivan - San Jose CA
Robert M. Pleva - Livermore CA
Thomas P. Matthews - San Jose CA

Assignee:

SPI Soft Pac International - San Jose CA

International Classification:

H04M 1106

US Classification:

379 96

Abstract:

An interactive graphics and audio communications system is disclosed. The system enables users to communicate audibly and graphically over a single telephone connection.

US Patent:

49435892, Jul 24, 1990

Filed:

Oct 27, 1988

Appl. No.:

7/263261

Inventors:

Phillip Crews - Santa Cruz CA
Thomas R. Matthews - Los Gatos CA
Paul Horton - Santa Cruz CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA
The Regents of the Univ. of California - Berkeley CA

International Classification:

A61K 3134
C07D40712

US Classification:

514468

Abstract:

This invention is directed to a method for treating helminthiasis which comprises administering to an animal in need thereof an anthelmintically effective amount of a compound of Formula (I): ##STR1## where R. sup. 1 is hydrogen or --SR. sup. 2, wherein R. sup. 2 is hydrogen, --C(O)--CH. sub. 3, or ##STR2## or a pharmaceutically acceptable salt thereof. This invention is also directed to a composition for treating helminthiasis in an animal which comprises a pharmaceutically acceptable excipient and an anthelmintically effective amount of a compound of Formula (I). This invention is also directed to novel compounds of Formula (I) wherein R. sup. 2 is ##STR3##.

US Patent:

47850124, Nov 15, 1988

Filed:

Apr 9, 1987

Appl. No.:

7/036267

Inventors:

Philip Crews - Santa Cruz CA
Thomas R. Matthews - Los Gatos CA
Emilio Q. Cabana - Santa Cruz CA
Madeline Adamczeski - Santa Cruz CA

Assignee:

Syntex Corporation - Palo Alto CA
The Regents of the University of California - Palo Alto CA

International Classification:

A61K 3142
C07D26332

US Classification:

514374

Abstract:

New oxazole derivatives of formula 1 and their pharmacetically acceptable salts have anthelmintic activity: ##STR1## where R is H, OH, or acyloxy of 8 to 22 carbon atoms; R. sub. 1, R. sub. 2, R. sub. 3, and R. sub. 4 are each independently H or acyl of 1 to 6 carbon atoms.

US Patent:

46846255, Aug 4, 1987

Filed:

Apr 19, 1985

Appl. No.:

6/725037

Inventors:

Deborah A. Eppstein - Palo Alto CA
Elizabeth Fraser-Smith - Los Altos CA
Thomas R. Matthews - Los Gatos CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

C07K 506
A61K 942

US Classification:

514 19

Abstract:

Co-administration of a muramyldipeptide derivative with liposomes enhances the anti-infective activity of the muramyldipeptide derivative.

US Patent:

45228116, Jun 11, 1985

Filed:

Jul 8, 1982

Appl. No.:

6/396213

Inventors:

Deborah A. Eppstein - Los Altos CA
Elizabeth B. Fraser-Smith - Los Altos CA
Thomas R. Matthews - Los Gatos CA

Assignee:

Syntex (U.S.A.) Inc. - Palo Alto CA

International Classification:

A61K 3702

US Classification:

514 2

Abstract:

Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides.

US Patent:

49593706, Sep 25, 1990

Filed:

Mar 29, 1989

Appl. No.:

7/330164

Inventors:

Phillip Crews - Santa Crux CA
Thomas R. Matthews - Los Gatos CA
Wayne D. Inman - Felton CA

International Classification:

A61K 3144
C07D47116

US Classification:

514280

Abstract:

This invention is directed to novel compounds of Formula (I): ##STR1## wherein R is hydrogen or methyl, or a pharmaceutically acceptable salt thereof and pharmaceutical compositions formulated therewith. This invention is also directed to a method for treating helminthiasis and for inhibiting reverse transcriptase activity in an animal by the administration of compounds of Formula (I).

US Patent:

48311359, May 16, 1989

Filed:

Jun 18, 1986

Appl. No.:

6/875486

Inventors:

Philip Crews - Santa Cruz CA
Thomas R. Matthews - Los Gatos CA
Emilio Quinoa - Santa Cruz CA
Madeline Adamczeski - Santa Cruz CA

Assignee:

The Regents of the University of California - Berkeley CA
Syntex (U.S.A.), Inc. - Palo Alto CA

International Classification:

C07D22310
A61K 3155

US Classification:

540526

Abstract:

Novel. delta. -caprolactam derivatives of formula I have anti-tumor, antibiotic and anthelmintic activity: ##STR1## wherein: R is H, lower alkyl, or lower acyl; R. sub. 1, R. sub. 2, and R. sub. 3 are each independently H or lower acyl; R. sub. 4 is H or acyl of 1 to 22 carbon atoms; R. sub. 5 is H or lower acyl; R. sub. 6 and R. sub. 7 are each H or OH, or R. sub. 6 and R. sub. 7 together form an epoxide or a double bond; and the pharmaceutically acceptable salts thereof.

US Patent:

20230005151, Jan 5, 2023

Filed:

Jul 8, 2022

Appl. No.:

17/860310

Inventors:

- Santa Clara CA, US
Rakesh Mathur - Santa Clara CA, US
Brent Mombourquette - Toronto, CA
Thomas Matthews - Santa Clara CA, US

International Classification:

G06T 7/00
G06V 10/764
G06V 10/25
G16H 30/40
G16H 50/20

Abstract:

The present disclosure provides methods and systems directed to performing real-time and/or AI-assisted radiology. A method for processing an image of a location of a body of a subject may comprise (a) obtaining the image of the location of a body of the subject; (b) using a trained algorithm to classify the image or a derivative thereof to a category among a plurality of categories, wherein the classifying comprises applying an image processing algorithm; (c) directing the image to a first radiologist for radiological assessment if the image is classified to a first category among the plurality of categories, or (ii) directing the image to a second radiologist for radiological assessment, if the image is classified to a second category among the plurality of categories; and (d) receiving a recommendation from the first or second radiologist to examine the subject based at least in part on the radiological assessment.