Thomas R May

US Patent:

6361758, Mar 26, 2002

Filed:

Oct 12, 2000

Appl. No.:

09/689507

Inventors:

Edward Anthony Pec - Gurnee IL
Daniel H. Robinson - Lake Bluff IL
Dennis A. Stephens - Mt. Prospect IL
Kathee Jantzi - Madison WI
Thomas Barton May - Grayslake IL
John Paul Oberdier - Gurnee IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 5100

US Classification:

424 117, 514167, 424236

Abstract:

Stable pharmaceutical formulations of a therapeutic agent, a low molecular weight alcohol and a glycol derivative are disclosed. Preferred formulations include 19-nor-1,3,25-trihydroxy-9,10-secoergosta-5,7(E),22(E)-triene.

US Patent:

20070105756, May 10, 2007

Filed:

Oct 30, 2006

Appl. No.:

11/589469

Inventors:

Thomas May - Grayslake IL, US
Richard Blessing - Vernon Hills IL, US
Sukumaran Menon - Gurnee IL, US
David Ostrow - Lake Zurich IL, US

International Classification:

A61K 38/14

US Classification:

514008000

Abstract:

A pharmaceutical composition containing vancomycin that has been treated to remove histamine and a method of removing histamine from a vancomycin preparation containing histamine.

US Patent:

20070105757, May 10, 2007

Filed:

Oct 30, 2006

Appl. No.:

11/589509

Inventors:

Thomas May - Grayslake IL, US
Richard Blessing - Vernon Hills IL, US
Sukumaran Menon - Gurnee IL, US
David Ostrow - Lake Zurich IL, US

International Classification:

A61K 38/14

US Classification:

514008000

Abstract:

Vancomycin composition treated to remove histamine and a method of removing histamine from vancomycin. The invention also includes an isolated polynucleotide sequence including an isolated polynucleotide sequence of histidine decarboxylase from . The vancomycin composition of the present invention is used to redue the incidence of Red Man Syndrome, phlebitis, and hypotension.

US Patent:

20070105758, May 10, 2007

Filed:

Oct 30, 2006

Appl. No.:

11/589599

Inventors:

Thomas May - Grayslake IL, US
Richard Blessing - Vernon Hills IL, US
Sukumaran Menon - Gurnee IL, US
David Ostrow - Lake Zurich IL, US

International Classification:

A61K 38/14

US Classification:

514008000

Abstract:

A time-released formulation of vancomycin. The invention also includes a vancomycin composition having a reduced level of histamine and a process for reducing the level of histamine in a vancomycin composition. The invention also includes a pharmaceutical composition containing vancomycin that reduces the incidence of Red Man Syndrome, phlebitis, and hypotension. The invention further includes a histamine-free growth media that supports growth of and the fermentation of vancomycin.

US Patent:

61403741, Oct 31, 2000

Filed:

Jul 15, 1999

Appl. No.:

9/354017

Inventors:

Thomas May - Grayslake IL
John Hofstetter - Vernon Hills IL
Kathleen L. Olson - Chicago IL
Sukumaran K. Menon - Gurnee IL
Bernard A. Mikrut - Lake Bluff IL
Clayton S. Ovenshire - Park Ridge IL
Lawrence John Rhodes - Lindenhurst IL
Earl R. Speicher - Buffalo Grove IL
James R. Waterson - Gurnee IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3105

US Classification:

514731

Abstract:

The present invention is directed to a sterile pharmaceutical composition comprising a propofol containing oil-in-water emulsion formulation having as an antimicrobial agent, a member selected from the group consisting of benzyl alcohol and sodium ethylene diamine tetraacetate; benzethonium chloride; and benzyl alcohol and sodium benzoate.

US Patent:

61367990, Oct 24, 2000

Filed:

Apr 8, 1998

Appl. No.:

9/057143

Inventors:

Edward Anthony Pec - Brookfield IL
Daniel H. Robinson - Lake Bluff IL
Dennis A. Stephens - Mt. Prospect IL
Kathee Jantzi - Madison WI
Thomas Barton May - Grayslake IL
John Paul Oberdier - Gurnee IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3159
A01N 4500

US Classification:

514167

Abstract:

Stable pharmaceutical formulations of a therapeutic agent, a low molecular weight alcohol and a glycol derivative are disclosed. Preferred formulations include 19-nor-1. alpha. ,3. beta. ,25-trihydroxy-9,10-secoergosta-5,7(E),22(E)-triene.

US Patent:

61403733, Oct 31, 2000

Filed:

Oct 23, 1998

Appl. No.:

9/178347

Inventors:

Thomas May - Grayslake IL
John Hofstetter - Vernon Hills IL
Kathleen L. Olson - Chicago IL
Sukumaran K. Menon - Gurnee IL
Bernard A. Mikrut - Lake Bluff IL
Clayton S. Ovenshire - Park Ridge IL
Lawrence John Rhodes - Lindenhurst IL
Earl R. Speicher - Buffalo Grove IL
James R. Waterson - Gurnee IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

A61K 3155

US Classification:

514731

Abstract:

The present invention is directed to a sterile pharmaceutical composition comprising a propofol containing oil-in-water emulsion formulation having as an antimicrobial agent, a member selected from the group consisting of benzyl alcohol and ethylene diamine tetra acetic acid; benzethonium chloride; and benzyl alcohol and sodium benzoate.