Thomas D Stevens

US Patent:

D3239977, Feb 18, 1992

Filed:

Oct 3, 1988

Appl. No.:

7/251872

Inventors:

James C. Masters - Walnut Creek CA
Thomas K. Stevens - El Cerrito CA

US Classification:

D10 69

US Patent:

53015118, Apr 12, 1994

Filed:

Jun 12, 1992

Appl. No.:

7/898080

Inventors:

Allen J. Bartlett - Milford MA
Charles A. Stochl - Cumberland RI
Anthony M. Guerra - Scituate MA
Dale A. Dopson - Stoughton MA
Paul Meroski - Melrose MA
Thomas F. Stevens - Westborough MA

Assignee:

Helix Technology Corporation - Mansfield MA

International Classification:

B01D 800

US Classification:

62 555

Abstract:

In a cryopump a frost concentrating device is affixed to a condensing cryopanel and provides surfaces for condensing gases which are cryopumped through an opening in the vacuum vessel. The surfaces of the frost concentrator extend towards the opening in the vacuum vessel and thus limit the amount of gases which condense on the surfaces of the condensing cryopanel facing the opening. The result is that the gap between the radiation shield and the condensing cryopanel does not become significantly narrowed by condensing gases, particularly in the area closest to the opening through which gases are cryopumped. This allows other gases to pass easily through the gap and condense on surfaces of the condensing cryopanel further away from the opening of the cryopump or to be adsorbed by an adsorbent material shielded by the condensing cryopanel.

US Patent:

20220315630, Oct 6, 2022

Filed:

Mar 15, 2022

Appl. No.:

17/695219

Inventors:

- Emeryville CA, US
Thomas Stevens - San Francisco CA, US
Rena Hill - Oakland CA, US
Carlos Gustavo Pesce - San Francisco CA, US
David N. Breslauer - San Francisco CA, US
Daniel M. Widmaier - San Francisco CA, US

International Classification:

C07K 14/435
C07K 14/395
C12P 21/02

Abstract:

The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include expression constructs, recombinant vectors, and recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to recombinant secretion signals that comprise the leader peptide of the a-mating factor (αMF) of and a non-αMF signal peptide.

US Patent:

20220306706, Sep 29, 2022

Filed:

May 23, 2022

Appl. No.:

17/751277

Inventors:

- Emeryville CA, US
Thomas Stevens - San Francisco CA, US
Rena Hill - Oakland CA, US
Carlos Gustavo Pesce - San Francisco CA, US

International Classification:

C07K 14/435
C07K 14/395
C12N 15/81
C12P 21/02
C12N 15/62

Abstract:

The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to at least 2 distinct secretion signals.

US Patent:

20210398648, Dec 23, 2021

Filed:

Aug 1, 2020

Appl. No.:

16/945803

Inventors:

Thomas Stevens - Moraga CA, US

International Classification:

G16H 20/70
G16H 50/70
G16H 10/60
G16H 50/30
G16H 40/67
G06Q 50/26
G16H 10/20
G06N 5/02
A61B 5/00
G09B 19/00

Abstract:

An application on a user's mobile device provides interaction and network support which may be based or supplemented with knowledge of the user's emotional state and risk of drug or alcohol dependency relapse. The user's emotional state may be determined in a number of interrelated and/or independent ways including asking the user to rate his/her state, games/quizzes, and/or pictures of the user, any one or more of which may be analyzed for emotional cues. The application establishes an emotional baseline, identifies triggers, tracks movements/activities, and helps the user stay on the road to recovery through consistent messaging, advice, ideas, and feedback. The user's network is notified if conditions point to a likely or imminent relapse and a response team may be automatically selected and notified to intercede in a virtual and/or physical intervention.

US Patent:

20190390228, Dec 26, 2019

Filed:

May 17, 2019

Appl. No.:

16/415605

Inventors:

- Emeryville CA, US
Thomas Stevens - San Francisco CA, US

International Classification:

C12N 15/90
C12N 15/62
C07K 16/14

Abstract:

Disclosed herein are modified strains for improving secretion of recombinantly expressed products secreted from a host organism with improved growth and productivity characteristics, as well as methods of using the modified strains.

US Patent:

20180282380, Oct 4, 2018

Filed:

Mar 13, 2018

Appl. No.:

15/920291

Inventors:

- Emeryville CA, US
Thomas Stevens - San Francisco CA, US
Rena Hill - Oakland CA, US
Carlos Gustavo Pesce - San Francisco CA, US
David N. Breslauer - San Francisco CA, US
Daniel M. Widmaier - San Francisco CA, US

International Classification:

C07K 14/435
C07K 14/395

Abstract:

The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include expression constructs, recombinant vectors, and recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to recombinant secretion signals that comprise the leader peptide of the α-mating factor (αMF) of and a non-αMF signal peptide.

US Patent:

20180282381, Oct 4, 2018

Filed:

Mar 13, 2018

Appl. No.:

15/920331

Inventors:

- Emeryville CA, US
Thomas Stevens - San Francisco CA, US
Rena Hill - Oakland CA, US
Carlos Gustavo Pesce - San Francisco CA, US

International Classification:

C07K 14/435
C07K 14/395

Abstract:

The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to at least 2 distinct secretion signals.