William P. Van Antwerp - Valencia CA, US Thomas J. Vasicek - Hopkins MN, US
Assignee:
MEDTRONIC, INC. - Minneapolis MN
International Classification:
A61K 38/21 A61M 5/142 A61P 31/14
US Classification:
604500, 424 857
Abstract:
Methods and devices for treating patients having chronic hepatitis C infection so as to eradicate detectable HCV-RNA and/or inhibit the emergence of a drug resistant HCV variant are disclosed. Certain methods of the invention involve the use of a continuous infusion pump in a multiphasic combination therapy using a therapeutically effective amount of a small molecule inhibitor such as ribavirin and a therapeutically effective amount of interferon-α.
Compositions And Methods For Treating Metabolic Diseases
Compositions comprising satiety peptides (e.g., PYY, PYY(3-36), GLP-1, oxyntomodulin, and cholecystokinin) and DPP-IV inhibitors and methods of treating metabolic diseases with such compositions are provided.
Peptide Yy Pharmaceutical Formulations, Compositions, And Methods
Pharmaceutical compositions comprising PYY (e.g., PYY(3-36) and analogs and variants thereof), satiety peptides, satiety hormones, metabolic hormones, and methods of treating metabolic diseases with such compositions are provided. Aspects include methods of increasing a feeling of fullness in patients treated with pharmaceutical compositions comprising PYY, PYY(3-36), satiety peptides, satiety hormones, metabolic hormones, and analogs, receptor antagonists and variants thereof.
Peptide Yy Pharmaceutical Formulations, Compositions, And Methods
- Minneapolis MN, US Thomas VASICEK - Minneapolis MN, US Beth Anne-Szkudlarek BROWN - Plymouth MN, US
International Classification:
A61K 38/22 A61K 9/00 A61P 3/04
Abstract:
Pharmaceutical compositions comprising PYY (e.g., PYY(3-36) and analogs and variants thereof), satiety peptides, satiety hormones, metabolic hormones, and methods of treating metabolic diseases with such compositions are provided. Aspects include methods of increasing a feeling of fullness in patients treated with pharmaceutical compositions comprising PYY, PYY(3-36), satiety peptides, satiety hormones, metabolic hormones, and analogs, receptor antagonists and variants thereof.
Compositions And Methods For Treating Metabolic Diseases
Compositions comprising satiety peptides (e.g., PYY, PYY(3-36), GLP-1, oxyntomodulin, and cholecystokinin) and DPP-IV inhibitors and methods of treating metabolic diseases with such compositions are provided.