Timothy M Block

US Patent:

6809083, Oct 26, 2004

Filed:

Feb 12, 1999

Appl. No.:

09/249220

Inventors:

Richard A. Mueller - Glencoe IL 60022
Martin L. Bryant - Los Altos CA 94024
Richard A. Partis - Evanston IL 63141
Gary S. Jacob - Creve Coeur MO 63141
Timothy M. Block - Jenkintown PA 19046
Raymond A. Dwek - Oxford OX1 3QU, GB

International Classification:

A01N 4304

US Classification:

514 45, 514 1, 514 42, 514 43, 514 89, 514277, 514315, 435 5

Abstract:

Provided are methods and compositions for treating hepatitis virus infections in mammals, especially humans. The methods comprise (1) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds alone or in combination with nucleoside antiviral agents, nucleotide antiviral agents, mixtures thereof, or immunomodulating/immunostimulating agents, or (2) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds alone or in combination with nucleoside antiviral agents, nucleotide antiviral agents, or mixtures thereof, and immunomodulating/immuno-stimulating agents.

US Patent:

20050267153, Dec 1, 2005

Filed:

Aug 3, 2004

Appl. No.:

10/910197

Inventors:

Richard Mueller - Glencoe IL, US
Martin Bryant - Carlisle MA, US
Richard Partis - Evanston IL, US
Gary Jacob - Creve Coeur MO, US
Timothy Block - Jenkintown PA, US
Raymond Dwek - Oxford, GB

International Classification:

A61K031/445

US Classification:

514328000, 514317000

Abstract:

Provided are methods and compositions for treating hepatitis virus infections in mammals, especially humans. The methods comprise (1) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds alone or in combination with nucleoside antiviral agents, nucleotide antiviral agents, mixtures thereof, or immunomodulating/immunostimulating agents, or (2) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds alone or in combination with nucleoside antiviral agents, nucleotide antiviral agents, or mixtures thereof, and immunomodulating/immuno-stimulating agents.