Timothy D Cutarelli from 23 Haver Farm Rd, Clinton, NJ 08809, age 51

Process And Intermediates For The Synthesis Of 2-(Quinolin-5-Yl)-4,5 Disubstituted-Azole Derivatives
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US Patent:

20080045718, Feb 21, 2008
Filed:

Aug 10, 2007
Appl. No.:

11/891348
Inventors:

Timothy Cutarelli - Basking Ridge NJ, US
Xiaoyong Fu - Edison NJ, US
Timothy McAllister - Westfield NJ, US
Michael Reeder - Skillman NJ, US
Jianguo Yin - Plainsboro NJ, US
Kelvin Yong - Lyndhurst NJ, US
Shuyi Zhang - Parsippany NJ, US
International Classification:

C07D 401/04
C07C 69/34
C07D 401/14
C07C 69/76
US Classification:

546167000, 560109000, 560190000
Abstract:

This application discloses a novel process to synthesize 2-(Quinolin-5yo)-4,5-Disubstituted-Azole derivatives, which may be used, for example, as PDE IV inhibitor compounds in pharmaceutical preparations.

Process For The Production Of Substituted 5-Quinolyl-Oxazoles And Pharmaceutically Acceptable Salts Thereof
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US Patent:

20100324295, Dec 23, 2010
Filed:

Jul 3, 2008
Appl. No.:

12/668192
Inventors:

Timothy D. Cutarelli - Clinton NJ, US
Dimitar L. Filipov - San Francisco CA, US
Christopher Stanley Pridgen - Union City NJ, US
Michael R. Reeder - Skillman NJ, US
Kelvin H. Yong - Lyndhurst NJ, US
Dimitrios N. Zarkadas - Fanwood NJ, US
International Classification:

C07D 413/14
C07D 413/02
US Classification:

546176
Abstract:

The present invention relates a process for the preparation of a compound of the formula:wherein R, R, R, Rand Rare as described herein. The compounds are inhibitors of phosphodiesterase 4 (PDE4).

Process And Intermediates For The Synthesis Of Heterocyclic Substituted Piperazines With Cxcr3 Antagonist Activity
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US Patent:

20110124867, May 26, 2011
Filed:

Dec 16, 2008
Appl. No.:

12/809101
Inventors:

Frank Xing Chen - Plainsboro NJ, US
Timothy D. Cutarelli - Clinton NJ, US
Xiayong Fu - Edison NJ, US
Xian Liang - Monmouth Junction NJ, US
Timothy L. McAllister - , US
Robert K. Orr - Cranford NJ, US
Jianguo Yin - Plainsboro NJ, US
Kelvin H. Yong - Lyndhurst NJ, US
Man Zhu - Clark NJ, US
Assignee:

Schering Corporation - Kenilworth NJ
International Classification:

C07D 413/14
C07D 401/14
C07D 403/04
C07D 241/04
C07D 211/44
US Classification:

544357, 544389, 546220
Abstract:

The present invention relates to novel processes for the preparation of the compound of the Formula A45:or a physiologically acceptable salt, solvate or prodrug thereof, which has utility, for example, as a pharmaceutically active compound with CXCR3 antagonist activity, and to novel intermediates useful in the synthesis thereof.

Timothy D Cutarelli