The present invention is directed to aqueous based formulations of water-soluble prodrugs of propofol. The formulations comprise in aqueous medium an effective amount of the water-soluble prodrug of propofol and an effective amount of an antioxidant. In one embodiment, the formulation also contains a tonicity modifier. The formulations are particularly useful as intravenous injections. The formulations preferably are buffered to a pH suitable for minimizing degradation of the prodrug during storage. Advantageously, the formulations can be prepared without the use of harmful co-solvents or surfactants, and are stable at room temperature over extended periods of time.
Otsuka America Pharmaceutical, Inc.
Manager
Harris Teeter since Oct 2010
Relief Pharmacist
Guilford Pharmaceuticals 2000 - 2004
Scientist II
Education:
Purdue University 1990 - 1996
phd, industrial and physical pharmacy
Howard University 1985 - 1990
BS pharm, Pharmacy
Oxon Hill High School 1981 - 1985
Skills:
Pharmaceuticals Fda Research Microsoft Office R&D Project Management Formulation Chemistry Technical Transfers Team Leadership Pharmaceutical Industry Clinical Research Chemistry Formulation Pharmaceutics Gmp Pharmacy Aseptic Processing Cmc Drug Development Quality Assurance Process Improvement Capa Clinical Development Technology Transfer Sop Ind Gxp Regulatory Affairs Clinical Trials
Interests:
Kids Cooking Exercise Medicine Investing Collecting Antiques Electronics Home Improvement Reading Fitness Gourmet Cooking Sports The Arts Collecting Home Decoration Health
Languages:
English
Certifications:
Certified Pharmaceutical Industry Professional (Cpip)
Oct 2004 to 2000 Executive Audit Secretary/IT SupportAbrams, Foster, Nole & Williams, P.A Baltimore, MD Dec 2009 to Apr 2010 IT/Change Management CoordinatorCareers USA, Jones Networking Baltimore, MD Mar 2001 to Oct 2004 Temporary Administrative AssistantDepartment of Human Services Washington, DC Apr 1999 to Dec 2000 Supervisory Computer Assistant
Education:
Community College of Baltimore County 2012 to 2014 Certificate in Databases and SpreadsheetsAxia College of University of Phoenix Phoenix, AZ 2007 to 2009 Associate in IT/Network AdministrationPSI Institute of Washington Silver Spring, MD 1986 to 1987 MS in Computer Programming
Skills:
Windows XP, Windows Vista, Windows 7, Windows 8, MS/Office Suites: Word, Outlook, Excel, Access, PowerPoint, Internet Explorer, Lotus Notes
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