Troy L Mccall

US Patent:

7276250, Oct 2, 2007

Filed:

Jul 3, 2002

Appl. No.:

10/189932

Inventors:

Anand R. Baichwal - Wappingers Falls NY, US
Troy W. McCall - Germantown TN, US

Assignee:

Penwest Pharmaceuticals Company - Danbury CT

International Classification:

A61K 9/22
A61K 9/26
A61K 9/36

US Classification:

424468, 424470, 424464, 424479, 424480, 424481, 424482

Abstract:

Sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof; methods for making the sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof; and methods for using the sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof to treat patients suffering from pain are provided.

US Patent:

20030091635, May 15, 2003

Filed:

Sep 25, 2002

Appl. No.:

10/254207

Inventors:

Anand Baichwal - Wappingers Falls NY, US
Paul Woodcock - Brookfield CT, US
Troy McCall - Germantown TN, US

International Classification:

A61K031/485
A61K009/22

US Classification:

424/468000, 514/282000

Abstract:

The invention provides opioid formulations having reduced potential for abuse, and having reduced potential for illegal sale and distribution. The opioid formulations of the invention comprise at least one opioid and a sustained release delivery system.

US Patent:

20030129234, Jul 10, 2003

Filed:

Jul 3, 2002

Appl. No.:

10/190383

Inventors:

Anand Baichwal - Wappingers Falls NY, US
Troy McCall - Germantown TN, US

Assignee:

Penwest Pharmaceuticals Company - Patterson NY

International Classification:

A61K031/485
A61K009/26

US Classification:

424/470000, 514/282000

Abstract:

Sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof; methods for making the sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof; and methods for using the sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof to treat patients suffering from pain are provided.

US Patent:

20030130297, Jul 10, 2003

Filed:

Jul 3, 2002

Appl. No.:

10/189897

Inventors:

Troy McCall - Germantown TN, US
David Lee - Wilmington DE, US

Assignee:

Endo Pharmaceuticals, Inc.

International Classification:

A61K031/485

US Classification:

514/282000

Abstract:

In a method of treating pain, a patient is administered a pharmaceutical composition of 6-hydroxy oxymorphone in amount sufficient to induce analgesia. In one embodiment, the pharmaceutical composition is administered orally. Any known or later developed method of oral delivery may be used. To achieve the desired analgesic effect, blood plasma levels of 6-hydroxy oxymorphone are raised to at least approximately 0.2 ng/mL. Most preferably blood plasma levels of 6-hydroxy oxymorphone range at least 0.3 ng/mL during treatment. Administration of compositions containing 6-hydroxy oxymorphone, and one or more carriers, diluents, and excipients in an amount sufficient to induce analgesia is also contemplated.

US Patent:

20030157167, Aug 21, 2003

Filed:

Jul 3, 2002

Appl. No.:

10/190192

Inventors:

Anand Baichwal - Wappingers Falls NY, US
Troy McCall - Germantown TN, US
David Lee - Wilmington DE, US

Assignee:

Endo Pharmaceuticals, Inc.

International Classification:

A61K031/485
A61K009/20
A61K009/22

US Classification:

424/468000, 514/282000

Abstract:

The invention pertains to a method of relieving pain by administering a controlled release pharmaceutical tablet containing oxymorphine which produces a mean minimum blood plasma level 12 to 24 hours after dosing, as well as the tablet producing the sustained pain relief.

US Patent:

20030228361, Dec 11, 2003

Filed:

Apr 7, 2003

Appl. No.:

10/408739

Inventors:

Anand Baichwal - Wappingers Fall NY, US
Paul Woodcock - Brookfield CT, US
Pradeepkumar Sanghvi - New Fairfeild CT, US
Dean Dinicola - Prospect CT, US
Troy McCall - Germantown TN, US

International Classification:

A61K009/22
A61K031/137

US Classification:

424/468000, 514/651000

Abstract:

The present invention relates to a sustained release oral dosage forms containing a therapeutically effective amount of metoprolol tartrate, methods of preparing such formulations, and to methods of treatment utilizing such formulations.

US Patent:

20040170684, Sep 2, 2004

Filed:

Dec 18, 2003

Appl. No.:

10/740213

Inventors:

Anand Baichwal - Wappingers Falls NY, US
Troy McCall - Germantown TN, US
Lirong Liu - Washington Township NJ, US
Steve Labudzinski - Poughkeepsie NY, US

Assignee:

Penwest Pharmaceuticals Co. - Patterson NY

International Classification:

A61K009/22

US Classification:

424/468000

Abstract:

Disclosed are sustained release oral solid dosage forms comprising a therapeutically effective amount of a medicament having a solubility of more than about 10 g/l; a pH modifying agent; and a sustained release matrix comprising a gelling agent, said gelling agent comprising a heteropolysaccharide gum and a homopolysaccharide gum capable of cross-linking said heteropolysaccharide gum when exposed to an environmental fluid, said dosage form providing a sustained release of said medicament after oral administration to human patients.

US Patent:

20040214849, Oct 28, 2004

Filed:

Jul 3, 2002

Appl. No.:

10/189653

Inventors:

Troy McCall - Germantown TN, US
David Lee - Wilmington DE, US

International Classification:

A61K031/485

US Classification:

514/282000

Abstract:

In a method of treating pain a patient is administered a pharmaceutical composition of 6-hydroxy oxymorphone in an amount sufficient to induce analgesia. In one embodiment, the pharmaceutical composition is administered parenterally, preferably by injection and intravenous drip. To achieve the desired analgesic effect, blood plasma levels of 6-hydroxy oxymorphone are raised to at least approximately 0.05 ng/mL. Most preferably blood plasma levels of 6-hydroxy oxymorphone range at least 0.075 ng/mL during treatment. Administration of compositions containing 6-hydroxy oxymorphone, and one or more carriers, diluents, and excipients in an amount sufficient to induce analgesia is also contemplated.