Dr. Kang graduated from the Johns Hopkins University School of Medicine in 1982. He works in New York, NY and 2 other locations and specializes in Neurology. Dr. Kang is affiliated with New York Presbyterian Hospital Columbia University Medical Center, New York Presbyterian Westchester Division and University Of Chicago Medicine.
The present invention provides methods and compositions for the therapeutic intervention of Parkinsons disease. More particularly, methods of making and sequestering dopamine are disclosed. Additionally, methods of genetically modifying donor cells by gene transfer for grafting into the central nervous system to treat defective, diseased or damaged cells are disclosed. Methods and compositions for carrying out such gene transfer and grafting are described.
Vesicular Monoamine Transporter Gene Therapy In Parkinson's Disease
The present invention provides methods and compositions for the therapeutic intervention of Parkinson's disease. More particularly, methods of making and sequestering dopamine are disclosed. Additionally, methods of genetically modifying donor cells by gene transfer for grafting into the central nervous system to treat defective, diseased or damaged cells are disclosed. Methods and compositions for carrying out such gene transfer and grafting are described.
Vesicular Monoamine Transporter Gene Therapy In Parkinson's Disease
The present invention provides methods and compositions for the therapeutic intervention of Parkinson's disease. More particularly, methods of making and sequestering dopamine are disclosed. Additionally, methods of genetically modifying donor cells by gene transfer for grafting into the central nervous system to treat defective, diseased or damaged cells are disclosed. Methods and compositions for carrying out such gene transfer and grafting are described.
Genetically Engineered Cells That Produce Produce L. Dopa
Un Jung Kang - Northbrook IL Fred H. Gage - La Jolla CA
Assignee:
Arch Development Corporation - Chicago IL
International Classification:
A61K 3500 A61K 4800 C12N 1585 C12N 1500
US Classification:
424 9321
Abstract:
The present invention provides a process of increasing dopamine production in a cell comprising co-transfecting the cell with one or more expression vectors containing polynucleotides that encode tyrosine hydroxylase, aromatic L-amino acid decarboxylase and GTP cyclohydrolase. Cells transfected with such vectors and the use of such transformed cells to increase dopamine production in the central nervous system of animals are also provided.
Un Kang 1999 graduate of Plano Senior High School in Plano, TX is on Classmates.com. See pictures, plan your class reunion and get caught up with Un and other high school alumni.