Usha B Patel

US Patent:

46721177, Jun 9, 1987

Filed:

Sep 16, 1985

Appl. No.:

6/776349

Inventors:

Magid A. Abou-Gharbia - Brandywood DE
Usha R. Patel - King of Prussia PA
Reinhardt P. Stein - Audubon PA

Assignee:

American Home Products Corporation - New York NY

International Classification:

C07D40106
C07D47104
C07D24136

US Classification:

544405

Abstract:

The compounds: ##STR1## in which R. sup. 1 is hydrogen, halogen, hydroxy, or alkyl; R. sup. 2 is substituted or unsubstituted pyridinyl, pyrazinyl, quinolinyl or quinoxalinyl and said substituents are alkyl, alkoxy, alkoxycarbonyl, halogen, cyano or nitro; R. sup. 5 and R. sup. 6 are, independently, hydrogen, alkyl, phenyl, halophenyl, methylphenyl, trifluoromethylphenyl, cyanophenyl or nitrophenyl; with the proviso that one of R. sup. 5 and R. sup. 6 is other than hydrogen; and n is an integer from 1 to 7; or a pharmaceutically acceptable salt thereof, are antipsychotic and anxiolytic agents.