Vernon Shane Pankratz

US Patent:

20110136129, Jun 9, 2011

Filed:

Dec 6, 2010

Appl. No.:

12/960894

Inventors:

Lynn C. Hartmann - Rochester MN, US
Marlene Frost - Burnsville MN, US
Carol Reynolds - Rochester MN, US
Vernon Pankratz - Rochester MN, US

International Classification:

C12Q 1/68

US Classification:

435 614

Abstract:

This document provides methods and materials involved in assessing the risk of developing breast cancer in patients with atypical hyperplasia. For example, methods and materials for using the level of Ki67 expression (e.g., percent Ki67cells or Ki67 staining intensity) to determine if a patient with atypical hyperplasia has an increased risk of developing breast cancer within an early phase from diagnosis (e.g., within ten years of biopsy) or an increased risk of developing breast cancer at a late phase from diagnosis (e.g., at a point more than ten years of biopsy) are provided.