Vicki S Thompson

US Patent:

6989276, Jan 24, 2006

Filed:

Dec 14, 2001

Appl. No.:

10/017577

Inventors:

Vicki S. Thompson - Idaho Falls ID, US
Karen B. Barrett - Meridian ID, US
Diane E. Key - Idaho Falls ID, US

Assignee:

Battelle Energy Alliance, LLC - Idaho Falls ID

International Classification:

G01N 33/543

US Classification:

436518, 436538, 436540, 435 71, 435 792, 435 793, 435971, 435973, 435975, 422 50, 422 56, 422 57, 422 60, 4241301

Abstract:

A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine, methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

US Patent:

7682797, Mar 23, 2010

Filed:

Apr 6, 2005

Appl. No.:

11/101216

Inventors:

Vicki S. Thompson - Idaho Falls ID, US
Karen B. Barrett - Meridian ID, US
Diane E. Key - Idaho Falls ID, US

Assignee:

Battelle Energy Alliance, LLC - Idaho Falls ID

International Classification:

G01N 33/00
G01N 33/543

US Classification:

435 71, 436501, 436518, 422 50

Abstract:

A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

US Patent:

7682798, Mar 23, 2010

Filed:

Apr 6, 2005

Appl. No.:

11/101254

Inventors:

Vicki S. Thompson - Idaho Falls ID, US
Karen B. Barrett - Meridian ID, US
Diane E. Key - Idaho Falls ID, US

Assignee:

Battelle Energy Alliance, LLC - Idaho Falls ID

International Classification:

G01N 33/00
G01N 33/543

US Classification:

435 71, 4351731, 435174, 4352831, 436501, 436518, 422 50, 422 57

Abstract:

A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

US Patent:

7695919, Apr 13, 2010

Filed:

Mar 26, 2007

Appl. No.:

11/691096

Inventors:

William A. Apel - Jackson WY, US
Vicki S Thompson - Idaho Falls ID, US

Assignee:

Battelle Energy Alliance, LLC - Idaho Falls ID

International Classification:

G01N 33/53

US Classification:

435 71, 435 792, 435 793, 435971, 435973, 435975, 436518, 436538, 436540, 422 50, 422 56, 422 57, 422 60, 4241301

Abstract:

A method for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method comprises attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to the antigens in the array to form immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, to form an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

US Patent:

7727755, Jun 1, 2010

Filed:

Nov 2, 2005

Appl. No.:

11/266063

Inventors:

Vicki S. Thompson - Idaho Falls ID, US
David N. Thompson - Idaho Falls ID, US
Kastli D. Schaller - Ammon ID, US
William A. Apel - Jackson WY, US

Assignee:

Battelle Energy Alliance, LLC - Idaho Falls ID

International Classification:

C12N 9/42

US Classification:

435209, 435 41, 435161

Abstract:

An enzyme isolated from an extremophilic microbe, and a method for utilizing same is described, and wherein the enzyme displays optimum enzymatic activity at a temperature of greater than about 80 C. , and a pH of less than about 2, and further may be useful in methodology including pretreatment of a biomass so as to facilitate the production of an end product.

US Patent:

7858353, Dec 28, 2010

Filed:

Jan 29, 2009

Appl. No.:

12/322359

Inventors:

David N. Thompson - Idaho Falls ID, US
William A. Apel - Jackson WY, US
Vicki S. Thompson - Idaho Falls ID, US
David W. Reed - Idaho Falls ID, US
Jeffrey A. Lacey - Idaho Falls ID, US
Emily D. Henriksen - Idaho Falls ID, US

Assignee:

Battelle Energy Alliance, LLC - Idaho Falls ID

International Classification:

C12N 9/42
C12N 9/14
C12N 9/00
C12N 15/00
C12P 21/06
C12P 19/34
C12Q 1/34
C08B 37/00
D21C 1/00
C07H 21/04

US Classification:

435209, 435195, 435183, 435 691, 4353201, 435 911, 435 18, 435274, 435277, 536 232, 536 231, 536 237

Abstract:

Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from.

US Patent:

7923234, Apr 12, 2011

Filed:

Jan 23, 2009

Appl. No.:

12/321636

Inventors:

David N. Thompson - Idaho Falls ID, US
Vicki S. Thompson - Idaho Falls ID, US
Kastli D. Schaller - Ammon ID, US
William A. Apel - Jackson WY, US
Jeffrey A. Lacey - Idaho Falls ID, US
David W. Reed - Idaho Falls ID, US

Assignee:

Battelle Energy Alliance, LLC - Idaho Falls ID

International Classification:

C12N 9/24
C07H 21/04

US Classification:

435200, 4352523, 4353201, 536 232

Abstract:

Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from and variations thereof are provided. Further provided are methods of at least partially degrading xylotriose and/or xylobiose using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from and variations thereof.

US Patent:

7960534, Jun 14, 2011

Filed:

Feb 26, 2009

Appl. No.:

12/380554

Inventors:

David N. Thompson - Idaho Falls ID, US
William A. Apel - Jackson WY, US
Vicki S. Thompson - Idaho Falls ID, US
David W. Reed - Idaho Falls ID, US
Jeffrey A. Lacey - Idaho Falls ID, US

Assignee:

Battelle Energy Alliance, LLC - Idaho Falls ID

International Classification:

C07H 21/04
C12N 15/63
C12P 21/00

US Classification:

536 237, 4353201, 435 701, 435 711

Abstract:

Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from are provided. Further provided are methods for transporting sugars across cell membranes using isolated and/or purified polypeptides and nucleic acid sequences from.