Waldemar G Derijk

US Patent:

8568763, Oct 29, 2013

Filed:

May 30, 2012

Appl. No.:

13/484086

Inventors:

Omran R. Abul-Khoudoud - Ashland KY, US
Catherine Cagiannos - Cincinnati OH, US
Waldemar G. DeRijk - Bartlett TN, US
Timothy C. Fabian - Memphis TN, US
Lisa Kyle Jennings - Memphis TN, US

Assignee:

The University of Tennessee Research Foundation - Knoxville TN

International Classification:

A61F 13/00
A61F 2/06
A61F 2/00
A61K 9/14
A61L 33/00

US Classification:

424423, 424422, 424486, 524548, 427 224, 427 225, 623 142

Abstract:

Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.

US Patent:

20060134218, Jun 22, 2006

Filed:

Jul 13, 2005

Appl. No.:

11/180195

Inventors:

Omran Abul-Khoudoud - Ashland KY, US
Catherine Cagiannos - Cincinnati OH, US
Waldemar DeRijk - Bartlett TN, US
Timothy Fabian - Memphis TN, US
Lisa Jennings - Memphis TN, US

International Classification:

A61F 2/06
A61K 9/14

US Classification:

424486000, 623001420

Abstract:

Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.

US Patent:

20160206600, Jul 21, 2016

Filed:

Aug 17, 2015

Appl. No.:

14/828418

Inventors:

- Knoxville TN, US
Catherine Cagiannos - Cincinnati OH, US
Waldemar DeRijk - Germantown TN, US
Timothy Fabian - Memphis TN, US
Lisa Jennings - Memphis TN, US

International Classification:

A61K 31/436

Abstract:

Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.

US Patent:

20140112968, Apr 24, 2014

Filed:

Sep 19, 2013

Appl. No.:

14/031835

Inventors:

- Knoxville TN, US
Catherine Cagiannos - Cincinnati OH, US
Waldemar Derijk - Germantown TN, US
Timothy C. Fabian - Memphis TN, US
Lisa Jennings - Memphis TN, US

International Classification:

A61L 27/34
A61L 27/54
A61K 31/436

US Classification:

424423, 514291, 427 21, 427 225

Abstract:

Water-soluble polymeric adhesive compositions and their use as delivery vehicles for carrying therapeutic agents on implantable devices, such as vascular grafts, are disclosed. Use of drug-coated vascular grafts is demonstrated for delivery of the therapeutic agents in vivo, thereby inhibiting restenosis or neointimal hyperplasia of the vascular graft and inhibiting infection at the vascular graft site. Methods of forming the adhesive and making the coated vascular grafts are also disclosed.