Wei He

US Patent:

7132282, Nov 7, 2006

Filed:

Jan 30, 2004

Appl. No.:

10/768350

Inventors:

Wei He - South Setauket NY, US
Wei Weng - Patchogue NY, US

Assignee:

Ingenious Targeting Inc. - Stony Brook NY

International Classification:

C12N 5/00
C12N 5/02
C12N 5/06
C12N 5/10
C12N 15/00

US Classification:

435354, 435325, 800 21, 800 25

Abstract:

The present invention relates generally to the field of generating genetically modified C57 mice. More particularly, the present invention pertains to 1) blastocyst-derived mouse embryonic stem cell (ES) cell lines including, but not limited to, the IC1, IC2, IAC1, IAC2, IAC3, IAC4, IAC5, IAC6, IAC7 or IAC8 ES cell line, 2) to efficient methods of making genetically modified C57 mice by introducing the modified C57 ES cells into the mouse blastocysts of either the same mouse strain and/or color of albino C57 strain, or other C57 strain, to generate genetically modified novel, useful and hereto unknown models of C57 mice, and to methods for identifying the chimerism of chimeras which can be not known by coat color.

US Patent:

20050265902, Dec 1, 2005

Filed:

May 27, 2004

Appl. No.:

10/855073

Inventors:

Ellen Chen - Patchogue NY, US
Wei He - South Setauket NY, US
Wei Weng - Patchogue NY, US

International Classification:

B01L009/00

US Classification:

422104000

Abstract:

The invention provides for improved multi-well plates and platforms that comprise a plurality of wells having increased volume capacity and clustered in a standard multi-well plate format and dimensions, said multi-well plate format being compatible with auxiliary equipment currently used and designed for the particular multi-well plate format. More particularly, the invention provides improved multi-well plates comprising a base to improve wells having one or more said wells having rectangular configuration, better retention of working materials and tissue culture ingredients than observed in conventional round-shaped wells. A cover is provided for protecting the assembly and cell cultures.