- La Jolla CA, US Nathaniel S. Wang - San Diego CA, US Martina Felderman - La Jolla CA, US Bolyn Hubby - Redwood City CA, US Heather D. Gouvis - San Diego CA, US Nicholas O. Fischer - Livermore CA, US Matthew A. Coleman - Oakland CA, US Angela Clare Evans - Livermore CA, US Wei He - Davis CA, US Amy Rasley - Livermore CA, US Craig D. Blanchette - San Leandro CA, US
International Classification:
A61K 9/127 A61K 48/00
Abstract:
Nanolipoprotein particles comprising at least a scaffold protein component and a membrane lipid component and related complexes, compositions, methods and systems are described, in which the membrane lipid component comprises at least one or more membrane forming lipids and one or more cationic lipids.
Combination Cancer Immunotherapies With Arginine Depletion Agents
Provided are arginine depletion agents such as ADI-PEG for use in combination with cancer immunotherapies, for example, immune checkpoint modulators and T-cell adoptive immunotherapies, for treating various cancers. Also provided are related methods, compositions, patient care kits, and cell cultures.
Engineered Chimeric Pegylated Adi And Methods Of Use
- Taipei, TW Robert Almassy - Vista CA, US Wei He - San Diego CA, US Richard E. Showalter - El Cajun CA, US Jiaojuan He - Shanghai, CN Yunyun Guo - Shanghai, CN James A. Thomson - San Diego CA, US
International Classification:
A61K 38/50 C12N 9/78 A61K 45/06
Abstract:
Provided are chimeric arginine deiminases, including pegylated chimeric arginine deiminases, and related compositions and methods of use thereof, including methods of treating cancer.
SingaporeSenior User Experience Designer at Hewlett Packard... Past: Human Factor Expert at Hewlett Packard, Senior User Experience Researcher at eBay, Senior...