Wei He

US Patent:

20050021577, Jan 27, 2005

Filed:

May 27, 2004

Appl. No.:

10/855174

Inventors:

Nagabhushana Prabhu - West Lafayette IN, US
Wei He - Memphis TN, US

International Classification:

G06F007/00

US Classification:

708200000

Abstract:

Various applications are presented of a vector field method of computing one or more eigenvalues and eigenvectors of a symmetric matrix. The vector field method computes an eigenvector by computing a discrete approximation to the integral curve of a special tangent vector field on the unit sphere. The optimization problems embedded in each iteration of the vector field algorithms admit closed-form solutions making the vector field approach relatively efficient. Among the several vector fields discussed is a family of vector fields called the recursive vector fields. Numerical results are presented that suggest that in some embodiments the recursive vector field method yields implementations that are faster than those based on the QR method. Further, the vector field method preserves, and hence can fully exploit the sparseness on the given matrix to speed up computation even further. Preprocessing that contracts the spectral radius of the given matrix further accelerates the systems.

US Patent:

20080254499, Oct 16, 2008

Filed:

Sep 22, 2006

Appl. No.:

12/067734

Inventors:

Philip Stewart Low - West Lafayette IN, US
Wei He - West Lafayette IN, US
Walter Anthony Henne - Lafayette IN, US
Derek David Doorneweerd - West Lafayette IN, US
Ji-Xin Cheng - West Lafayette IN, US

International Classification:

C12Q 1/02
C12M 1/00

US Classification:

435 29, 4352887

Abstract:

The invention relates to a method for diagnosing a disease state mediated by pathogenic cells, said method comprising the steps of administering to a patient a composition comprising a conjugate or complex of the general formula

US Patent:

20100055735, Mar 4, 2010

Filed:

Nov 2, 2007

Appl. No.:

12/513028

Inventors:

Philip Stewart Low - West Lafayette IN, US
Wei He - West Lafayette IN, US
Sumith A. Kularatne - West Lafayette IN, US

International Classification:

C12Q 1/06

US Classification:

435 39

Abstract:

The invention relates to a method for diagnosing a disease state mediated by pathogenic cells. The method comprises the steps of combining with an ex vivo patient sample a composition comprising a conjugate or complex of the general formulawherein the group Acomprises a ligand that binds to the pathogenic cells and the group X comprises an imaging agent, and detecting the pathogenic cells that express a receptor for the ligand using flow cytometry.

US Patent:

20140234866, Aug 21, 2014

Filed:

Feb 24, 2014

Appl. No.:

14/187844

Inventors:

- West Lafayette IN, US
Wei HE - West Lafayette IN, US
Sumith A. KULARATNE - West Lafayette IN, US

Assignee:

Purdue Research Foundation - West Lafayette IN

International Classification:

G01N 33/58

US Classification:

435 723

Abstract:

The invention relates to a method for diagnosing a disease state mediated by pathogenic cells. The method comprises the steps of combining with an ex vivo patient sample a composition comprising a conjugate or complex of the general formulawherein the group Acomprises a ligand that binds to the pathogenic cells and the group X comprises an imaging agent, and detecting the pathogenic cells that express a receptor for the ligand using flow cytometry.

Address:

1762 Mossy Oak Ln, Collierville, TN 38017

VIN:

5FNRL3H22AB028293

Make:

HONDA

Model:

ODYSSEY

Year:

2010