Wei C Wang

Address:

4703 Ladson Trl, Sugar Land, TX 77479

VIN:

4JGBB25E09A520897

Make:

MERCEDES BENZ

Model:

ML CLASS

Year:

2009

Address:

PO Box 16664, Sugar Land, TX 77496

Phone:

(281)7788858

VIN:

5FNYF284X7B008042

Make:

HONDA

Model:

PILOT

Year:

2007

US Patent:

7371364, May 13, 2008

Filed:

Aug 13, 2004

Appl. No.:

10/918009

Inventors:

Chun Li - Missouri City TX, US
Wei Wang - Sugar Land TX, US
Shi Ke - Missouri City TX, US

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61K 51/00
A61K 38/00
A61K 38/12
C07K 5/00
C07K 7/00
C07K 16/00
C07K 17/00

US Classification:

424 169, 514 9, 530317

Abstract:

The present invention relates to novel cyclic peptides that may be conjugated with imaging agents, including novel imaging agents. Specifically, it includes c(KRGDf; SEQ ID NO. 3) NIR imaging compositions and novel cyclic HWGFTL (SEQ ID NO. 5) polypeptides which may be used inter alia in NIR, MRI and nuclear imaging as well as therapy. Additionally, the invention includes novel imaging agents, such as TS-ICG derivatives. The invention also relates to methods of making and using such compounds. Such uses include both pre-operative and intraoperative detection of tumor cells and treatment monitoring.

US Patent:

20100290997, Nov 18, 2010

Filed:

May 11, 2007

Appl. No.:

12/227185

Inventors:

Chun Li - Missouri City TX, US
Wei Wang - Sugar Land TX, US
Marites P. Melancon - Houston TX, US
Juri G. Gelovani - Houston TX, US
Jeffrey Myers - Houston TX, US

International Classification:

A61K 49/06
C07D 403/10
C12Q 1/02
A61K 49/00

US Classification:

424 93, 548455, 435 29, 424 91

Abstract:

The disclosure includes a composition including a poly(L-glutamic acid) and a NIRF dye. It also includes a method including providing to a plurality of cells an imaging agent including poly(L-glutamic acid), a NIRF dye and then imaging the cells to detect the imaging agent. It further includes a dual functional contrast agent including an MRI agent conjugated with an optical imaging agent. A method of detecting cancer is provided including injecting a dual functional contrast agent into a patient and performing both an MRI and an optical scan. The presence of the agent may indicate cancer. A method of detecting cancer by injecting PG-DTPA-Gd-NIR813 into a patient, then detecting the presence or absence of Gd in a cell or tissue of the patient and detecting the presence or absence of NIR813 in a cell or tissue of the patient is provided. The presence of Gd and NIR813 may indicate cancer.

US Patent:

20120186825, Jul 26, 2012

Filed:

Dec 19, 2011

Appl. No.:

13/329462

Inventors:

Wei Wang - Sugar Land TX, US
Colin Longfield - Sugar Land TX, US
David Merlau - Friendswood TX, US
Sebastian Ives - Pearland TX, US
Brad Bailey - Katy TX, US
Belinda D. Manning - Pearland TX, US

International Classification:

E21B 34/06
E21B 34/00

US Classification:

166373, 166321

Abstract:

A remote actuation tool equipped with an intermediate volumetric mechanism for enhanced tool durability in high pressure differential downhole environments. Valve segments of the tool are actuated by power available due to a pressure differential between atmospheric and hydrostatic chambers of the tool. Yet, the intermediate volumetric mechanism, whether in the form of a discrete chamber or a hydraulic line system, minimizes stresses of the differential pressure on tool hydraulics. Thus, failure rates are substantially reduced. So, for example, the tool may be reliably employed in downhole environments which present differential pressures in excess of about 30,000 PSI.

US Patent:

20120244079, Sep 27, 2012

Filed:

May 6, 2010

Appl. No.:

13/319012

Inventors:

Shi Ke - Houston TX, US
Michel Mawad - Houston TX, US
Wei Wang - Houston TX, US

Assignee:

BAYLOR COLLEGE OF MEDICINE - Houston TX

International Classification:

C07D 403/08
A61K 49/04
A61K 49/00

US Classification:

424 944, 548455, 424 96, 424 91

Abstract:

The present invention provides nonradioactive NIR optical imaging agents based up on the structure of retinoid acid derivatives. The nonradioactive NIR optical imaging agent has been evaluated at the cellular level by confocal microscopy, and in vivo in a whole animal using a various xenograft models. The specific uptake of this agent in human cancer cells and multiple xenograft models demonstrate that nonradioactive near infrared dye labeled retinoid metabolites and/or analogs are useful for early stage cancer studies and diagnoses. Also, the present invention provides that nonradioactive near infrared dye labeled retinoid metabolites and/or analogs are useful for visualization of drug redistribution within the body which is useful in determining the optimal biological dose. Ultimately, the visualization data can be used as an analytical tool to reduce any systemic toxicity.

US Patent:

20130224115, Aug 29, 2013

Filed:

Apr 1, 2011

Appl. No.:

13/638060

Inventors:

Wei Wang - Houston TX, US
Jason Shohet - Houston TX, US
Michel Mawad - Houston TX, US
Shi Ke - Missouri City TX, US

Assignee:

Baylor College of Medicine - Houston TX

International Classification:

C07D 209/26

US Classification:

424 91, 548455

Abstract:

Multi-modal tumor imaging of neuroblastoma is essential for tumor staging, response evaluation and detection of relapsed diseased. The present invention provides a norepinephine analogue with a near-infrared (near-IR) dye, W765-BG, that efficiently and stably detects neuroblastoma in vivo using near-IR optical imaging. Confocal microscopy and optical imaging of neuroblastoma xenografts shows cell specific uptake and reveals exceptional tumor retention with a high tumor-to-tissue ratio up to 7 days after injection of W765-BG.

US Patent:

60002778, Dec 14, 1999

Filed:

Jun 5, 1998

Appl. No.:

9/092530

Inventors:

Marina Quiocho Smith - San Antonio TX
Wei Wang - Columbia MD
Carl Harry Popelar - San Antonio TX
James Alan Maple - Baytown TX

Assignee:

Southwest Research Institute - San Antonio TX

International Classification:

G01M 302
G01B 530

US Classification:

73 37

Abstract:

A method of predicting rupture failure for corroded transmission pipelines uses a model that accounts for the effects of residual and thermal stresses, and settlement of the pipe following installation. The pressure required for failure under a fixed bending moment is different from the pressure required wherein the same bending moment is produced by the settlement of the pipe because the bending compliance increases with plastic straining. The failure criterion depends upon whether or not the hoop strain exceeds the difference between the ultimate hoop strain limit of the material and the remaining hoop strain capacity needed for the material to shed the axial stresses due to bending.

US Patent:

20160332108, Nov 17, 2016

Filed:

May 16, 2016

Appl. No.:

15/155842

Inventors:

- San Ramon CA, US
Wei Wang - Katy TX, US

International Classification:

B01D 53/14

Abstract:

Elemental mercury is removed from a gas by contacting it with a halogen dissolved in an organic solvent. The mercury accumulates in the organic solvent and can be removed by extraction with an aqueous solution with a complexing agent, by adsorption, and by combinations. The absorption process can also operate by use of a series of absorbers which have successively higher concentrations of halogen in the solution and which successively remove more the mercury from the gas. A portion of the solvent in the last absorber can be cascaded to the previous absorber in the series. In one embodiment, the process is carried out at a temperature of absorber at less than or equal to 28 C. above the higher of the water dew in point and the hydrocarbon dew point. The mercury waste from the process is produced as either an aqueous solution or a small volume of mercuric sulfide.

US Patent:

20160304791, Oct 20, 2016

Filed:

Oct 27, 2015

Appl. No.:

14/923514

Inventors:

- San Ramon CA, US
Wei Wang - Houston TX, US
Nga Malekzadeh - Richmond CA, US

International Classification:

C10G 29/02
C10G 25/00
C10G 25/12

Abstract:

A process for removing non-volatile, particulate mercury from crudes and condensates is disclosed. Particulate mercury in crudes can be removed by a process of first adding a halogen, such as I. The halogen converts at least 10% of the particulate mercury into an oil-soluble mercury compound that cannot be removed by filtration or centrifugation. This oil-soluble mercury compound can then be removed by adsorption onto a solid adsorbent. The process can operate at near ambient conditions. The adsorption step can be carried out by mixing a particulate adsorbent in the halogen-treated crude and then removing it by centrifugation, desalting, filtration, hydrocyclone or by settling.