Wei Hua Yu

US Patent:

20130107254, May 2, 2013

Filed:

Sep 25, 2012

Appl. No.:

13/626421

Inventors:

Wei Wen Yu - College Park MD, US
Ian M. White - Ellicott City MD, US

Assignee:

University of Maryland, College Park - College Park MD

International Classification:

G01J 3/44

US Classification:

356301, 427162

Abstract:

A surface enhanced Raman spectroscopy (SERS) analytical device includes a substrate having a porous structure, and a plurality of plasmonic nanoparticles embedding in the porous structure and forming a sensing region. A method of detecting a target analyte in a sample includes contacting the sample with the substrate, whereby the target analyte, if present in the sample, is concentrated in the sensing matrix. The substrate may then be analyzed using SERS detection equipment.