Wendy W Yang - San Mateo CA, US Stan J Simon - San Mateo CA, US
International Classification:
G06F 7/00
US Classification:
707706
Abstract:
A system and method for managing and presenting entity information is described. In an illustrative implementation, information such as product availability and operating hours is stored in a server (). A query may be sent from a client () having a time (), date (), or both inquiring, for example, which entities are open at a certain or range of times, in the past, present or future. The server () compares the queried time with stored information, such as hours entries (). The results are displayed on a map () with open entities represented by a first symbol (R) and closed entities by a second symbol (G) such that all the entities on the map () are viewable without further searches. Clicking on a symbol () leads to a display () containing information about the associated entity, thereby enabling an entity's information to be found using only its location.
Methods For Detection Of Differences In Nucleic Acids
Qinghong Yang - Mountain View CA, US Wendy Yang - Mountain View CA, US Alla Lishanski - San Jose CA, US
International Classification:
C12Q001/68
US Classification:
435/006000
Abstract:
The present invention provides methods for detecting the presence or absence of a difference between two related nucleic acid sequences. In the methods, a target nucleic acid and a reference nucleic acid are contacted under conditions in which they are capable of forming a four-way nucleic acid complex with a branch structure that is capable of migration. Under the contact conditions, if the reference nucleic acid and target nucleic acid are identical, branch migration is capable of going to completion resulting in complete strand exchange. If the reference nucleic acid and target nucleic acid are different, branch migration does not go to completion, resulting in a stable four-way complex. Detection of the stable four-way complex identifies the presence of a difference between the nucleic acids. A stable four-way complex can be detected with molecules that specifically bind such complexes, by gel electrophoresis or by specific isolation of the stable four-way complex.
Methods For Detection Of Differences In Nucleic Acids
Qinghong Yang - Mountain View CA, US Wendy Yang - Mountain View CA, US Alla Lishanski - San Jose CA, US
International Classification:
C12Q001/68
US Classification:
435/006000
Abstract:
The present invention provides methods for detecting the presence or absence of a difference between two related nucleic acid sequences. In the methods, a target nucleic acid and a reference nucleic acid are contacted under conditions in which they are capable of forming a four-way nucleic acid complex with a branch structure that is capable of migration. Under the contact conditions, if the reference nucleic acid and target nucleic acid are identical, branch migration is capable of going to completion resulting in complete strand exchange. If the reference nucleic acid and target nucleic acid are different, branch migration does not go to completion, resulting in a stable four-way complex. Detection of the stable four-way complex identifies the presence of a difference between the nucleic acids. A stable four-way complex can be detected with molecules that specifically bind such complexes, by gel electrophoresis or by specific isolation of the stable four-way complex.
Apr 2012 to 2000 Staff pathologistLaboratory for Personalized Molecular Medicine San Diego, CA Dec 2011 to Mar 2012 Assistant Laboratory DirectorGenoptix, Inc Carlsbad, CA Aug 2010 to Mar 2012 Staff HematopathologistFreshGene, Inc Concord, CA Mar 2002 to Dec 2003 Acting Chief Executive OfficerFreshGene, Inc Mountain View, CA Feb 2000 to Feb 2001 Vice PresidentTerrapin Technologies, Inc South San Francisco, CA Sep 1996 to Aug 1997 Research AssociateHangzhou #12 High School Hangzhou, China Sep 1988 to Jul 1990 Chemistry Teacher
Education:
University of California at San Francisco San Francisco, CA 2009 to 2010 Clinical fellowship in Molecular Genetic PathologyColumbia University New York, NY 2008 to 2009 Clinical fellowship in HematopathologyUniversity of California at Los Angeles Los Angeles, CA 2004 to 2008 Clinical residency in Pathology and Laboratory MedicineUniversity of California at Davis Davis, CA Sep 1997 to Jun 2002 Doctor of Medicine (M.D.) in MedicineUC Berkeley, College of Marin & Santa Fe Community College Jan 1994 to Aug 1996 Pre-medical educationUniversity Of Florida Gainesville, FL 1992 to 1993 Graduate student in Immunology & Medical MicrobiologyCreighton University Omaha, NE 1990 to 1992 Graduate student in BiochemistryZhejiang University Hangzhou, CN Sep 1984 to Jul 1988 B.S. in Chemistry
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