- Foster City CA, US Eda Y. Canales - San Mateo CA, US Weng K. Chang - San Lorenzo CA, US Henok H. Kinfe - Foster City CA, US Scott E. Lazerwith - Burlingame CA, US Michael L. Mitchell - Castro Valley CA, US Yasamin Moazami - Seattle WA, US Scott D. Schroeder - Union City CA, US Daniel G. Shore - San Mateo CA, US Christopher J. Swank - San Mateo CA, US
International Classification:
C07D 519/00 C07D 495/04
Abstract:
The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.
- Foster City CA, US Weng K. Chang - San Lorenzo CA, US Laurent P. Debien - San Francisco CA, US Petr Jansa - Foster City CA, US Jennifer A. Loyer-Drew - Seattle WA, US Luisruben P. Martinez - San Mateo CA, US Stephane Perreault - Brier WA, US Gary B. Phillips - Issaquah WA, US Hyung-Jung Pyun - Fremont CA, US Roland D. Saito - San Mateo CA, US Michael S. Sangi - San Mateo CA, US Adam J. Schrier - Redwood City CA, US Marina E. Shatskikh - San Francisco CA, US James G. Taylor - Burlingame CA, US Jennifer A. Treiberg - Redmond WA, US Joshua J. Van Veldhuizen - Seattle WA, US
International Classification:
C07D 519/00 C07D 471/14 A61K 45/06
Abstract:
The present disclosure relates to novel compounds for use in therapeutic treatment of a disease associated with peptidylarginine deiminases (PADs), such as peptidylarginine deiminase type 4 (PAD4). The present disclosure also relates to processes and intermediates for the preparation of such compounds, methods of using such compounds and pharmaceutical compositions comprising the compounds described herein.
Sep 2011 to 2000 Graduate ResearcherProf. Emmanuel Theodorakis -UC San Diego, CA Jul 2009 to Jun 2011 Undergraduate ResearcherDr. H. Michael Petrassi- Genomics Institute of the Novartis Research Foundation
Jun 2010 to Sep 2010 Intern, Medicinal ChemistryProf. Milton Saier - University of California, San Diego La Jolla, CA May 2008 to Jun 2010 Lab Manager
Education:
Boston College Chestnut Hill, MA 2011 to 2000 Master in Organic ChemistryUniversity of California San Diego, CA 2006 to 2011 B.S. in Chemistry
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