William J Alston

US Patent:

20180224475, Aug 9, 2018

Filed:

Jan 16, 2018

Appl. No.:

15/872803

Inventors:

- Hayward CA, US
Don Lutz - Peoria AZ, US
William W. Alston - San Jose CA, US

International Classification:

G01N 35/00
G01N 15/06
G01N 15/02
G01N 1/22

Abstract:

A device for counting particles on a sample surface includes a scanner probe having a first opening for receiving particles from a sample surface and one or more second openings, a particle detector for detecting particles passed there-through, a modulator for modulating air flowing there-through, a pump for producing a first airstream flowing from the first opening and through the particle detector, and for producing a second airstream flowing through the modulator and to the one or more second openings, and control circuitry for controlling the modulator to modulate an amplitude of the second airstream.

US Patent:

20180093050, Apr 5, 2018

Filed:

Apr 13, 2016

Appl. No.:

15/566372

Inventors:

Alex Stenzler - Long Beach CA, US
- Worthing, BB
Arthur Slutsky - Toronto, CA
Steven Ellis - Oro-medonte, CA
Noe Zamel - Toronto, CA
William Alston - San Jose CA, US

International Classification:

A61M 15/00

Abstract:

A dry powder inhaler dispenses a partial dosage of a powder from a dry powder chamber during a single user inhalation. In certain embodiments, the dry powder chamber is a dry powder capsule that spins in a chamber with a protrusion for limiting the spin of the capsule. In certain embodiments, a capsule slides in a proximal and distal direction for dispensing partial dosages of powder medicament. Air inlets in communication whit the external environment can be included in the inhaler housing for generating a smooth inhalation experience for the user and facilitating operation of partial dosage mechanisms. In other embodiments, a hinged member, sliding member, rotating member, spring tensioned member, pressure actuated valve, dry powder chamber with patterned holes or combinations of these are used as a mechanism for dispensing a partial dosage of powder medicament during a single inhalation.

US Patent:

20180093051, Apr 5, 2018

Filed:

Apr 13, 2016

Appl. No.:

15/566351

Inventors:

Alex Stenzler - Long Beach CA, US
- Worthing, BB
Arthur Slutsky - Toronto, CA
Steven Ellis - Ontario, CA
Noe Zamel - Toronto, CA
William Alston - San Jose CA, US

International Classification:

A61M 15/00
A61M 15/06

Abstract:

Described is a dry powder inhaler for inhalation of a dry powder composition. The inhaler includes an external housing that defines an internal passage. The inhaler also includes a mouthpiece, a compartment for holding a dry powder capsule or powder reservoir, and a powder fluidization and deagglomeration apparatus for directing airflow to the dry powder to generate airborne powder particles within the internal passage. When a user inhales through the mouthpiece, a first airflow pattern is generated that has a first airflow resistance, during which the fluidization and deagglomeration apparatus generates airborne dry powder particles within the internal passage. Upon reaching a threshold negative pressure value within the internal passage of the inhaler, a second airflow pattern is generated having a second airflow resistance that is lower than the first airflow resistance, which pulls the airborne dry powder into the user's lungs during the inhalation. Embodiments of elastomeric valves are also described.