Elisabetta Vegeto - Houston TX Donald P. McDonnell - San Diego CA Bert W. OMalley - Houston TX William T. Schrader - San Diego CA Ming-Jer Tsai - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C12Q 163
US Classification:
435 6, 4352351, 435325, 536 231
Abstract:
The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid hormone receptor agonist. The present invention also provides plasmids containing mutated steroid hormone receptor proteins and cells transfected with those plasmids. In addition, the present invention provides methods for determining whether a compound is a steroid hormone receptor antagonist or agonist. Also, the present invention provides methods of determining endogenous ligands for steroid hormone receptors. The invention further provides a molecular switch for regulating expression in gene therapy and methods of employing the molecular switch in humans, animals, transgenic animals and plants.
Mutated Steroid Hormone Receptors, Methods For Their Use And Molecular Switch For Gene Therapy
Elisabetta Vegeto - Houston TX Donald P. McDonnell - San Diego CA Bert W. O'Malley - Houston TX William T. Schrader - Houston TX Ming-Jer Tsai - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
A61K 3170 A61K 4800
US Classification:
514 44
Abstract:
The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid hormone receptor agonist. The present invention also provides plasmids containing mutated steroid hormone receptor proteins and cells transfected with those plasmids. In addition, the present invention provides methods for determining whether a compound is a steroid hormone receptor antagonist or agonist. Also, the present invention provides methods of determining endogenous ligands for steroid hormone receptors. The invention further provides a molecular switch for regulating expression in gene therapy and methods of employing the molecular switch in humans, animals, transgenic animals and plants.
Mutated Steroid Hormone Receptors, Methods For Their Use And Molecular Switch For Gene Therapy
Elisabetta Vegeto - Houston TX Donald P. McDonnell - San Diego CA Bert W. O'Malley - Houston TX William T. Schrader - Houston TX Ming-Jer Tsai - Houston TX
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
C07K 1300 C07H 2104
US Classification:
530350
Abstract:
The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid hormone receptor agonist. The present invention also provides plasmids containing mutated steroid hormone receptor proteins and cells transfected with those plasmids. In addition, the present invention provides methods for determining whether a compound is a steroid hormone receptor antagonist or agonist. Also, the present invention provides methods of determining endogenous ligands for steroid hormone receptors. The invention further provides a molecular switch for regulating expression in gene therapy and methods of employing the molecular switch in humans, animals, transgenic animals and plants.
Childrens Orthopedic SgyCenter For Orthopedics & Sports Medicine 215 W Bowery St STE 7200, Akron, OH 44308 (330)5433500 (phone), (330)5435001 (fax)
Education:
Medical School University of Cincinnati College of Medicine Graduated: 1983
Procedures:
Hallux Valgus Repair Hip/Femur Fractures and Dislocations Knee Arthroscopy Lower Arm/Elbow/Wrist Fractures and Dislocations Lower Leg/Ankle Fractures and Dislocations Shoulder Surgery Spinal Fusion Spinal Surgery
Conditions:
Fractures, Dislocations, Derangement, and Sprains Hallux Valgus Internal Derangement of Knee Internal Derangement of Knee Cartilage Intervertebral Disc Degeneration
Languages:
English
Description:
Dr. Schrader graduated from the University of Cincinnati College of Medicine in 1983. He works in Akron, OH and specializes in Orthopedic Pediatric Surgery. Dr. Schrader is affiliated with Akron Childrens Hospital.
Name / Title
Company / Classification
Phones & Addresses
William Schrader Owner
B&J Antique Auto Parts Ret Auto/Home Supplies
3508 21 Ave W, Bradenton, FL 34205
William G. Schrader Managing
William George Schrader Consulting LLC
799 Tropical Cir, Sarasota, FL 34242
William T. Schrader
WTS MARKETING, INC
William W Schrader
SCHRADER 9150, LLC
William W. Schrader
SCHRADER 10944, LLC
William Schrader Treasurer
West Coast Federal Employees Credit Union Federal Credit Union · Commercial Banks, Not Chartered
3487 Clark Rd, Sarasota, FL 34231 PO Box 17185, Sarasota, FL 34276 Sarasota, FL 34243 (941)9252890
William Conrad Schrader Director
SCHRADER SPRAY COATING COMPANY, INC
William Schrader Director
OIL DATA INC
745 Atlantic Ave FL 7, Boston, MA 02111 1616 S Voss Rd 870, Houston, TX 77057
forgiven, those who hide their sins "will be less credible, and will be trusted less, because others will not be able to see any of their indiscretionsthe things that make them human and more trustworthy." A handful of people will try to go off-grid, predicts William Schrader, founder of PSINet. T
Date: Dec 18, 2014
Category: Sci/Tech
Source: Google
Ultrafast Internet opens up new possibilities: experts
"As gigabit bandwidth becomes widespread later this decade, applications will emerge which exploit the combination of big data, GPS location, weather, personal-health monitoring devices, industrial production, and much more," said William Schrader, co-founder of PSINet Inc.
Date: Oct 09, 2014
Category: Sci/Tech
Source: Google
Holograms, VR and telepresence: Experts herald the coming Gigabit Age
There are a lot of expansive predictions of what 2025 technology will enable humans to do contained in the report but it was William Schrader, the co-founder of the first commercial ISP, who highlighted that the precise nature of those transformational changes is generally unknown.
Under the arrangement, Elliott will support five new directors at Hess John Krenicki, Fredric Reynolds, William Schrader, Kevin Meyers and Mark Williams while adding three of its own Rodney Chase, Harvey Golub and David McManus to the board, with representation on the nominating and governan
Date: May 16, 2013
Category: Business
Source: Google
Hess outlines proposed asset sales as it refocuses
chair John Krenicki Jr., former ConocoPhillips senior vice president of E&P Kevin Meyers, former Deloitte LLP CEO James Quigley, former CBS Corp. CEO Fredric Reynolds, former TNK-BP chief operating officer William Schrader and former Royal Dutch Shell plc executive committee member Mark Williams.
Date: Mar 05, 2013
Category: Business
Source: Google
Hess to Sell Gas Stations as Part of a Shift in Strategy
nd perhaps most prominent, Hess named six new directors to its board, most of whom are former oil industry executives. They include John Krenicki Jr., a former head of GE Energy; William Schrader, a former chief operating officer of TNK-BP; and James H. Quigley, a former chief executive of Deloitte.