Xi Sophia Chen

US Patent:

20120040966, Feb 16, 2012

Filed:

Dec 28, 2009

Appl. No.:

13/142678

Inventors:

Joseph A. Maddry - Birmingham AL, US
Bill Severson - Birmingham AL, US
Colleen B. Jonsson - Louisville KY, US
James W. Noah - Sterrett AL, US
Diana L. Noah - Sterrett AL, US
Xi Chen - Hoover AL, US

Assignee:

Southern Research Institute Office of Commercialization and Intellectual Prop - Birmingham AL

International Classification:

A61K 31/55
C07D 405/10
C07D 401/04
C07D 491/052
C07D 495/04
A61P 31/16
A61K 31/517
A61K 31/519
A61K 31/5377
C12Q 1/70
A61P 31/12
A61P 31/14
C07D 239/70
C07D 471/04

US Classification:

514215, 544249, 544250, 544115, 540586, 514267, 5142328, 435 5

Abstract:

The compounds provided herein are suitable for inhibiting a virus in a patient and for treating a patient suffering from a viral infection such as an influenza virus. Also provided is a method for screening of compounds for use in treating and preventing viral infections. The assay screens compounds for activity against an influenza virus by measuring the cytopathogenic effect (CPE) of the compound on influenza infected-cells using percent cell viability as the end point.

US Patent:

20220415309, Dec 29, 2022

Filed:

Jun 24, 2021

Appl. No.:

17/304712

Inventors:

- Seattle WA, US
Jingqian Zhao - Bellevue WA, US
Prathap Ramachandra - Kirkland WA, US
Jinning Wu - Seattle WA, US
Uday Kumar Kollu - Seattle WA, US
Xi Chen - Issaquah WA, US
Wenbo Yan - Seattle WA, US
Charlotte Alizerine Dzialo - Seattle WA, US
Liu Yang - Seattle WA, US

International Classification:

G10L 15/18
G06F 16/687
G10L 15/22

Abstract:

A speech processing system uses contextual data to determine the specific domains, subdomains, and applications appropriate for taking action in response to spoken commands and other utterances. Some applications may be given priority over others such that some applications are general request applications to which responsibility for processing an intent is to be assigned as long as contextual criteria are satisfied, while other applications are specific request applications to which responsibility for processing an intent is to be assigned only if the applications are specifically requested, if the contextual criteria of priority applications are not satisfied, and/or if certain contextual criteria associated with the specific request applications are satisfied.

US Patent:

20220415311, Dec 29, 2022

Filed:

Jun 24, 2021

Appl. No.:

17/304720

Inventors:

- Seattle WA, US
Adam Kalman - Seattle WA, US
Uday Kumar Kollu - Seattle WA, US
Ruiqi Luo - Kenmore WA, US
Xi Chen - Issaquah WA, US
Jingqian Zhao - Bellevue WA, US
Yunqiang Zhu Zhu - Sammamish WA, US
Adriano Devillaine - Seattle WA, US

International Classification:

G10L 15/18
G10L 15/22

Abstract:

A speech processing system uses contextual data to determine the specific domains, subdomains, and applications appropriate for taking action in response to spoken commands and other utterances. The system can use signals and other contextual data associated with an utterance, such as location signals, content catalog data, data regarding historical usage patterns, data regarding content visually presented on a display screen of a computing device when an utterance was made, other data, or some combination thereof.

US Patent:

20220415320, Dec 29, 2022

Filed:

May 16, 2022

Appl. No.:

17/745671

Inventors:

- Menlo Park CA, US
Lin Sun - Kenmore WA, US
Ram Kumar Hariharan - Kirkland WA, US
Haidong Wang - Clyde Hill WA, US
Joshua Saylor McMullen - Kirkland WA, US
Mengxi Li - Bellevue WA, US
Long You Cai - Kirkland WA, US
Keith Diedrick - Kirkland WA, US
Crystal Annette Nakatsu Sung - Redmond WA, US
Xi Chen - San Jose CA, US
Debojeet Chatterjee - Sunnyvale CA, US
Sonal Gupta - Sunnyvale CA, US
Vikas Seshagiri Rao Bhardwaj - Seattle WA, US
Yashar Mehdad - Redwood City CA, US
Anuj Kumar - Kirkland WA, US
Ashish Garg - Bellevue WA, US
Justin Denney - San Francisco CA, US
Hakan Inan - Emerald Lake Hills CA, US
Iaroslav Markov - San Mateo CA, US
Surya Teja Appini - Mountain View CA, US
Bing Liu - Sunnyvale CA, US
Shusen Liu - Mountain View CA, US
Zhiqi Wang - Redmond WA, US
Alexander Kolmykov-Zotov - Sammamish WA, US

International Classification:

G10L 15/22
G06F 40/35

Abstract:

In one embodiment, a system includes an automatic speech recognition (ASR) module, a natural-language understanding (NLU) module, a dialog manager, one or more agents, an arbitrator, a delivery system, one or more processors, and a non-transitory memory coupled to the processors comprising instructions executable by the processors, the processors operable when executing the instructions to receive a user input, process the user input using the ASR module, the NLU module, the dialog manager, one or more of the agents, the arbitrator, and the delivery system, and provide a response to the user input.

US Patent:

20220315553, Oct 6, 2022

Filed:

Jun 8, 2022

Appl. No.:

17/835551

Inventors:

- Orange Beach AL, US
Xi Chen - Hoover AL, US
Adam B. Keeton - Gardendale AL, US
Michael R. Boyd - Orange Beach AL, US

Assignee:

ADT Pharmaceuticals, LLC - Orange Beach AL

International Classification:

C07D 317/64
A61K 31/445
A61K 31/44
A61K 31/40
A61K 31/401
A61K 31/36
A61K 31/341
C07D 211/56
C07D 213/75
C07D 207/14
C07D 207/337
C07D 307/54
C07C 235/32
C07C 237/20
C07D 235/30
C07D 405/12
C07D 213/24
C07D 307/38
C07D 307/52
A61K 45/06
C07C 233/58

Abstract:

Disclosed are compounds, for example, compounds of formula I,wherein R, R, R-R, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.

US Patent:

20210261572, Aug 26, 2021

Filed:

Apr 26, 2019

Appl. No.:

17/047787

Inventors:

- Orange Beach AL, US
Xi CHEN - Hoover AL, US

Assignee:

ADT PHARMACEUTICALS, LLC - Orange Beach AL

International Classification:

C07F 5/02
C07D 307/52
C07D 213/40
C07C 235/32
C07D 213/56
C07D 261/08
C07D 277/28
C07D 317/12
C07D 327/04
C07D 231/40

Abstract:

Disclosed are compounds for medical uses, for example, compounds of formula (Ia), wherein A, A, A, A, A, A, A, R, Rand E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.

US Patent:

20200223815, Jul 16, 2020

Filed:

Mar 30, 2020

Appl. No.:

16/834267

Inventors:

- Orange Beach AL, US
Xi Chen - Hoover AL, US
Adam B. Keeton - Gardendale AL, US
Michael R. Boyd - Orange Beach AL, US

Assignee:

ADT Pharmaceuticals, LLC - Orange Beach AL

International Classification:

C07D 317/64
A61K 31/445
A61K 31/44
A61K 31/40
A61K 31/401
A61K 31/36
A61K 31/341
C07D 211/56
C07D 213/75
C07D 207/14
C07D 207/337
C07D 307/54
C07C 235/32
C07C 237/20
C07D 235/30
C07D 405/12
C07D 213/24
C07D 307/38
C07D 307/52
A61K 45/06
C07C 233/58

Abstract:

Disclosed are compounds, for example, compounds of formula I,wherein R, R, R-R, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.

US Patent:

20200223816, Jul 16, 2020

Filed:

Mar 30, 2020

Appl. No.:

16/834348

Inventors:

- Orange Beach AL, US
Xi Chen - Hoover AL, US
Adam B. Keeton - Gardendale AL, US
Michael R. Boyd - Orange Beach AL, US

Assignee:

ADT Pharmaceuticals, LLC - Orange Beach AL

International Classification:

C07D 317/64
A61K 31/445
A61K 31/44
A61K 31/40
A61K 31/401
A61K 31/36
A61K 31/341
C07D 211/56
C07D 213/75
C07D 207/14
C07D 207/337
C07D 307/54
C07C 235/32
C07C 237/20
C07D 235/30
C07D 405/12
C07D 213/24
C07D 307/38
C07D 307/52
A61K 45/06
C07C 233/58

Abstract:

Disclosed are compounds, for example, compounds of formula I,wherein R, R, R-R, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition, for example, cancer.