Xiang Zheng

US Patent:

6746872, Jun 8, 2004

Filed:

Jan 16, 2002

Appl. No.:

10/055788

Inventors:

Xiang Yang Zheng - Fremont CA
Brian Earp - San Jose CA
Herbert Chow - South San Francisco CA
Christa Hartmann - Oakland CA

Assignee:

LifeScan, Inc. - Milpitas CA

International Classification:

G01N 3386

US Classification:

436 16, 436 8, 436 69, 436 79, 422 61, 422 73, 600369, 73 6441

Abstract:

Compositions, methods, devices and kits for use in the calibration of coagulation tests. The control compositions include particles capable of aggregating in plasma and calcium ions which, when mixed with plasma, simulate the behavior of whole blood in a coagulation test. The methods include providing calcium ions and particles capable of aggregating in plasma, combining the particles and calcium ions with plasma to form a control composition, and applying the control composition to a coagulation test. The devices include a container having at least two compartments, with one compartment including particles that promote or induce aggregation of a protein or proteins in plasma, and the other compartment includes a solution of calcium ions. The kits include a control composition including a container of calcium ions, a container of particles capable of inducing aggregation of proteins in plasma, and one or more coagulation test devices.

US Patent:

7453811, Nov 18, 2008

Filed:

Apr 8, 2004

Appl. No.:

10/821354

Inventors:

Steven V. Luong - San Jose CA, US
Heidi H. Ou - San Jose CA, US
Rena W. Yang - Sunnyvale CA, US
Xiang Zheng - Santa Clara CA, US

Assignee:

Cisco Technology, Inc. - San Jose CA

International Classification:

G01R 31/08

US Classification:

370237, 370351

Abstract:

Disclosed are methods and apparatus for handling Link State Packets (LSPs) sent between processing nodes within a computer network. At a first node, an LSP sent by a second node is received. The received LSP specifies connectivity information regarding the second node. It is then determined whether one of two conditions is met: either the received LSP is an updated LSP even though it appears older and a corresponding stored LSP fails authentication, or the received LSP fails authentication and it appears newer. If it is determined that one of these conditions is met, as well as purging criteria, then updating procedures are then performed on the LSP information that is maintained by the first node, where the LSP information was originally obtained from a corresponding LSP sent by the second node.

US Patent:

20040166552, Aug 26, 2004

Filed:

Feb 19, 2004

Appl. No.:

10/783815

Inventors:

Xiang Zheng - Fremont CA, US
Brian Earp - San Jose CA, US
Herbert Chow - South San Francisco CA, US
Christa Hartmann - Oakland CA, US

International Classification:

C12Q001/56

US Classification:

435/013000

Abstract:

Compositions, methods, devices and kits for use in the calibration of coagulation tests. The control compositions comprise particles capable of aggregating in plasma and calcium ions which, when mixed with plasma, simulate the behavior of whole blood in a coagulation test. The methods comprise providing calcium ions and particles capable of aggregating in plasma, combining the particles and calcium ions with plasma to form a control composition, and applying the control composition to a coagulation test. The devices comprise a container having at least two compartments, with one compartment including particles that promote or induce aggregation of a protein or proteins in plasma, and the other compartment includes a solution of calcium ions. The kits comprise a control composition comprising a container of calcium ions, a container of particles capable of inducing aggregation of proteins in plasma, and one or more coagulation test devices.

US Patent:

6261519, Jul 17, 2001

Filed:

Jul 16, 1999

Appl. No.:

9/356248

Inventors:

Ian A. Harding - San Mateo CA
Robert Justice Shartle - Livermore CA
Xiang Jennifer Zheng - Fremont CA
Philip John Cizdziel - San Jose CA

Assignee:

Lifescan, Inc. - Milpitas CA

International Classification:

G01N 3348

US Classification:

422 58

Abstract:

A fluidic medical diagnostic device permits measurement of analyte concentration or a property of a biological fluid, particularly the coagulation time of blood. The device has at one end a sample port for introducing a sample and at the other end a bladder for drawing the sample to a measurement area. A first channel carries the sample from the sample port to the measurement area, and a stop junction, between the measurement area and bladder, halts the sample flow. A second channel, which runs from the first channel to an edge of the device, determines whether the sample volume is sufficient to permit an accurate measurement. The desired measurement can be made by placing the device into a meter, which measures a physical property of the sample, typically optical transmittance, after it has interacted with one or more reagents on the device.