Xiaodong Cheng - League City TX, US Fang Mel - League City TX, US Travis Young - Galveston TX, US Jinsong Liu - Houston TX, US
International Classification:
A61K 31/7088 A61P 35/00 C12Q 1/68
US Classification:
435006000, 514044000
Abstract:
The present invention discloses the link between oncogenic Ras and TSG101 and the negative effect of TSG101 on the expression of p21 in ovarian cancer. The present also discloses the use of TSG101 as a prognostic, diagnostic marker and a potential therapeutic target in cancer, especially ovarian cancer.
Methods And Compositions For Treating Chronic Pain
Xiaodong Cheng - Houston TX, US Fang Mei - Houston TX, US Annemieke Kavelaars - Houston TX, US Cobi J. Heijnen - Houston TX, US
Assignee:
The Board of Regents of the University of Texas System - Austin TX
International Classification:
A61K 31/42
Abstract:
Certain embodiments are directed to methods of treating pain, e.g., chronic or neuropathic pain, comprising administering an effective amount of an EPAC inhibitor.
Methods Of Treating Rickettsia Using Exchange Proteins Directly Activated By Camp (Epacs) Inhibitors