Dong Xu - Nashua NH, US Xiaoping S. Yang - Nashua NH, US Wendell Kong - Hollis NH, US Lee M. Mohnkern - Bedford NH, US Phillip M. Smith - Hollis NH, US Pane-chane Chao - Nashua NH, US
Assignee:
BAE Systems Information and Electronic Systems Integration Inc. - Nashua NH
International Classification:
H01L 21/335 H01L 29/778
US Classification:
257194, 257183, 257E21403, 257E29246
Abstract:
A high-power and high-gain ultra-short gate HEMT device has exceptional gain and an exceptionally high breakdown voltage provided by an increased width asymmetric recess for the gate electrode, by a composite channel layer including a thin indium arsenide layer embedded in the indium gallium arsenide channel layer and by double doping through the use of an additional silicon doping spike. The improved transistor has an exceptional 14 dB gain at 110 GHz and exhibits an exceptionally high 3. 5-4 V breakdown voltage, thus to provide high gain, high-power and ultra-high frequency in an ultra-short gate device.
Biao Luo - Lexington MA, US David Root - Brookline MA, US Xiaoping Yang - Brookline MA, US Gregory Hinkle - Plymouth MA, US
International Classification:
C40B 40/08 C40B 50/06
US Classification:
435006000, 435091200
Abstract:
Described herein is a method of cloning synthetic oligos (including in situ synthesized oligos) into an (one or more) expression vector for library (e.g., shRNA library) production. The oligos are synthesized with one portion of the first stem of the hairpin, followed by a first loop sequence, the complete second stem, a second loop sequence, and finished with the remaining portion of the first stem of the hairpin. The two portions of the first stem anneal to the second stem, juxtaposing the 5′ end close to the 3′ end of the oligo. The methods described herein selected for hairpins with perfectly base-paired stems. After annealing, a ligase is added to the annealed oligos and the base-paired hairpins are preferentially annealed, and ligated, creating closed circular oligos. The now circularized hairpins served as templates for rolling circle amplification using a polymerase with high processivity. One or more primers complementary to the two strands of the amplified double stranded circular hairpins initiate the rolling circle amplification in the presence of a polymerase. Using primers (e.g., a sense and antisense primer), the rolling circle amplification yields double stranded hairpin sequences. These can be digested (e.g., using restriction enzymes) to produce a double-stranded hairpin fragment encoding a single hairpin. The fragment can be cloned into an appropriately digested vector for a variety of uses including expression.
Asymmetrically Recessed High-Power And High-Gain Ultra-Short Gate Hemt Device
BAE Systems Information and Electronics Systems Integration Inc. - , US Xiaoping S. Yang - Nashua NH, US Wendell Kong - Hollis NH, US Lee M. Mohnkern - Bedford NH, US Phillip M. Smith - Hollis NH, US Pane-chane Chao - Nashua NH, US
Assignee:
BAE Systems Information and Electronics Systems Integration inc. - Nashua NH
International Classification:
H01L 29/66
US Classification:
438172
Abstract:
A high-power and high-gain ultra-short gate HEMT device has exceptional gain and an exceptionally high breakdown voltage provided by an increased width asymmetric recess for the gate electrode, by a composite channel layer including a thin indium arsenide layer embedded in the indium gallium arsenide channel layer and by double doping through the use of an additional silicon doping spike. The improved transistor has an exceptional 14 dB gain at 110 GHz and exhibits an exceptionally high 3.5-4 V breakdown voltage, thus to provide high gain, high-power and ultra-high frequency in an ultra-short gate device.
Portsmouth Anesthesia AssociatesPortsmouth Anesthesia Associates PC 5818 Harbour Vw Blvd, Suffolk, VA 23435 (757)3997451 (phone), (757)3991158 (fax)
Education:
Medical School Inner Mongolia Med Coll, Hohhot City, Inner Mongolia Auto Reg, China Graduated: 1982
Languages:
English
Description:
Dr. Yang graduated from the Inner Mongolia Med Coll, Hohhot City, Inner Mongolia Auto Reg, China in 1982. He works in Portsmouth, VA and 2 other locations and specializes in Anesthesiology. Dr. Yang is affiliated with Bon Secours DePaul Medical Center and Bon Secours Maryview Medical Center.
Broad Institute Jan 2005 - Jan 2016
Manager of Rnai Production and Development, the Rnai Consortium
Functional Genomics Consortium Broad Institute of Mit and Harvard Jan 2005 - Jan 2016
Senior Group Leader
Broad Institute Aug 2001 - Jan 2005
Manager of Finishing Laboratory
Education:
Harvard University 1999 - 2001
New York University 1993 - 1998
Doctorates, Doctor of Philosophy, Nanotechnology
Skills:
Molecular Biology Dna Genetics Genomics Pcr Rna Interference High Throughput Screening Biochemistry Statistical Data Analysis Molecular Cloning Assay Development Bioinformatics Cell Biology Microscopy Cell Culture Fluorescence Microscopy Western Blotting Laboratory Automation Scientific Writing Dna Sequencing Qpcr Rt Pcr Transfection Flow Cytometry Rna Isolation Tissue Culture Statistics Cancer Protein Expression Protein Engineering Vector Design Oracle Sql Developer Perl Script R Data Mining Drug Resistance Nanotechnology Genome Sequencing Sequence Analysis Nextgen
Interests:
Cooking Pierce School of Brookline Reading Ma (2007 10) Ma (2008 09) Baseball Coach Baseball Coach Math League Coach Brookline Youth Baseball Ma (2008 09)
Certifications:
Data Analysis Mathematical Biostatistics Boot Camp 1 Sun Certified Programmer For Java 2 Platform Sql and Pl/Sql Certified By Oracle. Coursera