Sheng C. Lou - Libertyville IL Jeffrey C. Hunt - Mundelein IL John G. Konrath - Lake Villa IL Xiaoxing Qiu - Gurnee IL James W. Scheffel - Mundelein IL Joan D. Tyner - Beach Park IL
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Monoclonal Antibodies That Recognize A Shared Epitope Between The Human Immunodeficiency Virus Type 1 (Hiv-1) Capsid (Ca/P24) And The Human Immunodeficiency Virus Type 2 (Hiv-2) Capsid (Ca/P26)
Sheng C. Lou - Libertyville IL, US Jeffrey C. Hunt - Mundelein IL, US John G. Konrath - Lake Villa IL, US Xiaoxing Qiu - Gurnee IL, US James W. Scheffel - Mundelein IL, US Joan D. Tyner - Beach Park IL, US
Assignee:
Abbott Laboratories, Inc. - Abbott Park IL
International Classification:
C12P 21/08
US Classification:
53038835, 422 61
Abstract:
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Monoclonal Antibodies That Recognize A Shared Epitope Between The Human Immunodeficiency Virus Type 1 (Hiv-1) Capsid (Ca/P24) And The Human Immunodeficiency Virus Type 2 (Hiv-2) Capsid (Ca/P26)
Sheng C. Lou - Libertyville IL, US Jeffrey C. Hunt - Mundelein IL, US John G. Konrath - Lake Villa IL, US Xiaoxing Qiu - Gurnee IL, US James W. Scheffel - Mundelein IL, US Joan D. Tyner - Beach Park IL, US
Assignee:
Abbott Laboratories, Inc. - Abbott Park IL
International Classification:
C12P 21/08
US Classification:
53038835
Abstract:
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Monoclonal Antibodies That Recognize A Shared Epitope Between The Human Immunodeficiency Virus Type 1 (Hiv-1) Capsid (Ca/P24) And The Human Immunodeficiency Virus Type 2 (Hiv-2) Capsid (Ca/P26)
Sheng C. Lou - Libertyville IL, US Jeffrey C. Hunt - Mundelein IL, US John G. Konrath - Lake Villa IL, US Xiaoxing Qiu - Gurnee IL, US James W. Scheffel - Mundelein IL, US Joan D. Tyner - Beach Park IL, US
Assignee:
Abbott Laboratories, Inc. - Abbott Park IL
International Classification:
C12P 21/08
US Classification:
53038835, 422 61
Abstract:
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Monoclonal Antibodies That Recognize A Shared Epitope Between The Human Immunodeficiency Virus Type 1 (Hiv-1) Capsid (Ca/P24) And The Human Immunodeficiency Virus Type 2 (Hiv-2) Capsid (Ca/P26)
Sheng C. Lou - Libertyville IL, US Jeffrey C. Hunt - Mundelein IL, US John G. Konrath - Lake Villa IL, US Xiaoxing Qiu - Gurnee IL, US James W. Scheffel - Mundelein IL, US Joan D. Tyner - Beach Park IL, US
Assignee:
Abbott Laboratories, Inc. - Abbott Park IL
International Classification:
C12P 21/08
US Classification:
53038835, 422 61
Abstract:
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Monoclonal Antibodies That Recognize A Shared Epitope Between The Human Immunodeficiency Virus Type 1 (Hiv-1) Capsid (Ca/P24) And The Human Immunodeficiency Virus Type 2 (Hiv-2) Capsid (Ca/P26)
Sheng C. Lou - Libertyville IL, US Jeffrey C. Hunt - Mundelein IL, US John G. Konrath - Lake Villa IL, US Xiaoxing Qiu - Gurnee IL, US James W. Scheffel - Mundelein IL, US Joan D. Tyner - Beach Park IL, US
Assignee:
Abbott Laboratories, Inc. - Abbott Park IL
International Classification:
C12P 21/08
US Classification:
53038835, 422 61
Abstract:
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Monoclonal Antibodies That Recognize A Shared Epitope Between The Human Immunodeficiency Virus Type 1 (Hiv-1) Capsid (Ca/P24) And The Human Immunodeficiency Virus Type 2 (Hiv-2) Capsid (Ca/P26).
Sheng C. Lou - Libertyville IL, US Jeffrey C. Hunt - Mundelein IL, US John G. Konrath - Lake Villa IL, US Xiaoxing Qiu - Gurnee IL, US James W. Scheffel - Mundelein IL, US Joan D. Tyner - Beach Park IL, US
Assignee:
Abbott Laboratories, Inc. - Abbott Park IL
International Classification:
C12P 21/08
US Classification:
53038835
Abstract:
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Methods For The Detection Of Hiv-1 Or -2 Antigens Employing Monoclonal Antibodies That Recognize A Shared Hiv-1/-2 Epitope In The Capsid P24/P26 Proteins
Sheng C. Lou - Libertyville IL, US Jeffrey C. Hunt - Mundelein IL, US John G. Konrath - Lake Villa IL, US Xiaoxing Qiu - Gurnee IL, US James W. Scheffel - Mundelein IL, US Joan D. Tyner - Beach Park IL, US
Assignee:
Abbott Laboratories - Abbott Park IL
International Classification:
C12Q 1/70 G01N 33/53 A61K 39/42
US Classification:
435 5, 435 71, 4241481, 4241601
Abstract:
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.