Xin Chen

US Patent:

7700594, Apr 20, 2010

Filed:

Nov 15, 2006

Appl. No.:

11/599663

Inventors:

Xin Chen - Farmingdale NY, US
Heather Coate - Farmingdale NY, US
Andrew Philip Crew - Farmingdale NY, US
Ayako Honda - Farmingdale NY, US
Mark Joseph Mulvihill - Farmingdale NY, US
Paula A. R. Tavares - Farmingdale NY, US
Jing Wang - Farmingdale NY, US
Douglas S. Werner - Farmingdale NY, US
Kristen Michelle Mulvihill - Farmingdale NY, US
Kam W. Siu - Farmingdale NY, US
Bijoy Panicker - Farmingdale NY, US
Apoorba Bharadwaj - Farmingdale NY, US
Lee D. Arnold - Farmingdale NY, US
Meizhong Jin - Farmingdale NY, US
Brian Volk - Farmingdale NY, US
Qinghua Weng - Farmingdale NY, US
James David Beard - Farmingdale NY, US

Assignee:

OSI Pharmaceuticals, Inc. - Melville NY

International Classification:

C07D 487/04
C07D 401/14
C07D 403/04
A61K 31/53
A61K 31/4523
A61K 35/00

US Classification:

514243, 544184

Abstract:

Compounds represented by Formula (I).

US Patent:

8111957, Feb 7, 2012

Filed:

Jul 7, 2009

Appl. No.:

12/498591

Inventors:

Robert R Alfano - Bronx NY, US
Xin Chen - Corning NY, US
Joohyun Koh - Painted Post NY, US
Ming-Jun Li - Horseheads NY, US
Daniel Aloysius Nolan - Corning NY, US
Henry Sztul - New York NY, US

Assignee:

Corning Incorporated - Corning NY

International Classification:

G02B 6/26
G01N 21/00

US Classification:

385 28, 356 731

Abstract:

Generation of a cylindrically polarized light beam, and in particular, a hybrid-azimuthal-radial polarization beams, called HARP modes, generated from an input linearly polarized Gaussian beam using a spun optical waveguide device is taught. The HARP modes are comprised of hybrid-azimuthal polarization (HAP) and hybrid-radial polarization (HRP) superposition modes. These beams possess a non-zero local angular momentum density that is spatially varying and a zero total angular momentum.

US Patent:

20070208053, Sep 6, 2007

Filed:

Jan 18, 2007

Appl. No.:

11/654814

Inventors:

Lee Arnold - Farmingdale NY, US
Xin Chen - Farmingdale NY, US
Hanqing Dong - Farmingdale NY, US
Andrew Garton - Farmingdale NY, US
Mark Mulvihill - Farmingdale NY, US
Colin Sambrook Smith - Oxford, GB
Gerard Thomas - Oxford, GB
Thomas Krulle - Oxford, GB
Jing Wang - Farmingdale NY, US

International Classification:

C07D 471/02
A61K 31/4745

US Classification:

514300000, 546113000

Abstract:

Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X, X, X, X, X, X, X, R, and Qare defined herein, inhibit kinase enzymes and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer. The compounds are also useful in the treatment of inflammation, allergy, asthma, disease and conditions of the immune system, disease and conditions of the nervous system, cardiovascular diseases, disease and conditions of the eye, dermatological diseases, osteoporosis, diabetes, multiple sclerosis, and infections.

US Patent:

20130231306, Sep 5, 2013

Filed:

Jan 25, 2013

Appl. No.:

13/749758

Inventors:

Dan Sherman - New York NY, US
Rama Devi Appari - Port Jefferson Station NY, US
Xin Chen - Commack NY, US
Ramesh Chilukuri - Budha Nagar near Uppal Depot NY, US
Hanqing Dong - Syosset NY, US
Caterina Ferraro - Fresh Meadows NY, US
Kenneth Foreman - Syosset NY, US
Ramesh C. Gupta - Port Jefferson Station NY, US
An-Hu Li - Commack NY, US
Kathryn M. Stolz - Williston Park NY, US
Brian Volk - Sayville NY, US
Robert Zahler - Pennington NJ, US

Assignee:

OSI Pharmaceuticals, LLC - Farmingdale NY

International Classification:

C07F 9/6558
C07F 9/6544
C07F 9/6512

US Classification:

514 81, 544232, 514 86, 544105, 544 57, 514 80, 514 82

Abstract:

Compounds of Formula 1, as shown below and defined herein:

US Patent:

20220411860, Dec 29, 2022

Filed:

Jul 12, 2021

Appl. No.:

17/373295

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Xiaoxu Li - New York NY, US
Xin Chen - New York NY, US
Zengmin Li - Flushing NY, US
Shiv Kumar - Belle Meade NJ, US
Shundi Shi - Ozone Park NY, US
Cheng Guo - Brooklyn NY, US
Jianyi Ren - New York NY, US
Minchen Chien - Tenafly NJ, US
Chuanjuan Tao - Fort Lee NJ, US
Ece Erturk - New York NY, US
Sergey Kalachikov - Bronx NY, US
James J. Russo - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/6869
C07H 19/10
C07H 19/14
C07H 19/20

Abstract:

Disclosed herein, inter alfa, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

US Patent:

20230028388, Jan 26, 2023

Filed:

Aug 1, 2022

Appl. No.:

17/816555

Inventors:

- New York NY, US
Xiaoxu Li - New York NY, US
Xin Chen - New York NY, US
Zengmin Li - Flushing NY, US
Shiv Kumar - Belle Meade NJ, US
Shundi Shi - Ozone Park NY, US
Cheng Guo - Brooklyn NY, US
Jianyi Ren - New York NY, US
Minchen Chien - Tenafly NJ, US
Chuanjuan Tao - Fort Lee NJ, US
Ece Erturk - New York NY, US
Sergey Kalachikov - Bronx NY, US
James J. Russo - New York NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/6869
C07H 19/10
C07H 19/20
C07H 19/14

Abstract:

Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

US Patent:

20210285041, Sep 16, 2021

Filed:

Mar 28, 2018

Appl. No.:

16/498132

Inventors:

Jingyue Ju - Englewood Cliffs NJ, US
Xiaoxu Li - New York NY, US
Xin Chen - New York NY, US
Shiv Kumar - Belle Mead NJ, US
James Russo - New York NY, US
Minchen Chien - Tenafly NJ, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

C12Q 1/6869
C07H 19/10
C07H 19/20

Abstract:

Disclosed herein, inter alia, are nucleotide analogues, and methods of use thereof, having cleavable orthogonal linkers.

US Patent:

20200069717, Mar 5, 2020

Filed:

May 23, 2017

Appl. No.:

16/303715

Inventors:

- New York NY, US
Xin Chen - New York NY, US
Xiaoxu Li - New York NY, US
Zengmin Li - Flushing NY, US
Minchen Chien - Tenafly NJ, US
Shundi Shi - Ozone Park NY, US
Jianyi Ren - New York NY, US
Cheng Guo - Brooklyn NY, US
Shiv Kumar - Belle Mead NJ, US
James J. Russo - New York NY, US
Chuanjuan Tao - Fort Lee NJ, US
Steffen Jockusch - New York NY, US
Sergey Kalachikov - Bronx NY, US

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

A61K 31/7052
C07H 21/04

Abstract:

Disclosed herein, inter alia, are compounds, compositions, and methods of thereof in the sequencing a nucleic acid.