Xin J Wang

US Patent:

20030170678, Sep 11, 2003

Filed:

Oct 25, 2002

Appl. No.:

10/281456

Inventors:

Rudolph Tanzi - Hull MA, US
Kenneth Becker - San Diego CA, US
Gonul Velicelebi - San Diego CA, US
Kathryn Elliott - San Diego CA, US
Xin Wang - San Diego CA, US
Lars Bertram - Brighton MA, US
Aleister Saunders - Philadelphia PA, US
Deborah Blacker - Newton MA, US

Assignee:

Neurogenetics, Inc.

International Classification:

C12Q001/68

US Classification:

435/006000

Abstract:

Genetic markers associated with Alzheimer's disease are provided. Also provided are methods of determining the presence or absence in a subject of one or more polymorphisms associated with Alzheimer's disease and methods of determining the level of risk for Alzheimer's disease in a subject. Further provided are nucleic acid compositions and kits for use in determining the presence or absence in a subject of one or more polymorphisms associated with Alzheimer's disease and kits for determining the level of risk for Alzheimer's disease in a subject.

US Patent:

20130252843, Sep 26, 2013

Filed:

Nov 22, 2011

Appl. No.:

13/988495

Inventors:

Mingdi Yan - Tewksbury MA, US
Xin Wang - Portland OR, US

Assignee:

THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTL - Portland OR

International Classification:

G01N 33/58

US Classification:

506 9, 436 94, 436 86, 506 32

Abstract:

Disclosed embodiments concern differentiating and classifying one or more targets using a perhalophenylazide-derived nanoparticle probe, or multiple such probes. Particular embodiments concern using statistical analysis to produce score plots illustrating the level of differentiation and/or classification. Also disclosed are methods for making perhalophenylazide-derived nanoparticle probes, individually or by using a microarray technique. Particular embodiments concern methods for using the per halophenylazide-derived nanoparticle probes to diagnose, detect, and/or treat a disease. Kits comprising the perhalophenylazide-derived nanoparticle probes are also disclosed.

US Patent:

D4455266, Jul 24, 2001

Filed:

Oct 29, 1999

Appl. No.:

D/113046

Inventors:

Xin Wang - Cambridge MA

Assignee:

Litecontrol Corporation - Hanson MA

International Classification:

2605

US Classification:

D26 76

US Patent:

20220339270, Oct 27, 2022

Filed:

Apr 29, 2020

Appl. No.:

17/607141

Inventors:

- Cambridge MA, US
Todd Carter - Cambridge MA, US
Jinzhao Hou - Cambridge MA, US
Yanqun Shu - Cambridge MA, US
Giridhar Murlidharan - Malden MA, US
Martin Goulet - Weston MA, US
Dinah Wen-Yee Sah - Hopkinton MA, US
Steven Paul - Cambridge MA, US
Xin Wang - Arlington MA, US
Hiu Yan Chung - Cambridge MA, US

Assignee:

Voyager Therapeutics, Inc. - Cambridge MA

International Classification:

A61K 39/00
A61P 25/28
C12N 7/00
C12N 15/86

Abstract:

The disclosure provides compositions and methods for the preparation, manufacture and therapeutic use of viral vectors, such as adeno-associated virus (AAV) particles having viral genomes encoding one or more antibodies or antibody fragments or antibody-like polypeptides, for the prevention and/or treatment of diseases and/or disorders.

US Patent:

20220333131, Oct 20, 2022

Filed:

Dec 23, 2021

Appl. No.:

17/561252

Inventors:

- Cambridge MA, US
Xin Wang - Arlington MA, US
Pengcheng Zhou - Lexington MA, US
Dinah Wen-Yee Sah - Hopkinton MA, US

International Classification:

C12N 15/86
C12N 7/00
C12N 15/113

Abstract:

The present invention relates to adeno-associated viral (AAV) particles modulatory polynucleotides encoding at least one siRNA molecules and methods of use thereof.

US Patent:

20200377887, Dec 3, 2020

Filed:

Sep 21, 2018

Appl. No.:

16/649244

Inventors:

- Cambridge MA, US
Xin Wang - Arlington MA, US
Dinah Wen-Yee Sah - Hopkinton MA, US
Pengcheng Zhou - Lexington MA, US

International Classification:

C12N 15/113
C12N 15/86
A61P 25/28

Abstract:

The present invention relates to adeno-associated viral (AAV) particles encoding siRNA molecules and methods for treating Huntington's Disease (HD).

US Patent:

20200270635, Aug 27, 2020

Filed:

May 4, 2018

Appl. No.:

16/611046

Inventors:

- Cambridge MA, US
Xin Wang - Arlington MA, US
Pengcheng Zhou - Cambridge MA, US
Dinah Wen-Yee Sah - Cambridge MA, US

International Classification:

C12N 15/86
C12N 7/00
C12N 15/113

Abstract:

The present invention relates to adeno-associated viral (AAV) particles modulatory polynucleotides encoding at least one siRNA molecules and methods of use thereof.

US Patent:

20200155624, May 21, 2020

Filed:

May 4, 2018

Appl. No.:

16/611041

Inventors:

- Cambridge MA, US
Fen Chen - Cambridge MA, US
Pengcheng Zhou - Cambridge MA, US
Xin Wang - Arlington MA, US
Yanqun Shu - Cambridge MA, US
Jinzhao Hou - Cambridge MA, US

International Classification:

A61K 35/76
C12N 7/00
A61P 25/14
C12N 15/113
C12N 15/86

Abstract:

The present invention relates to adeno-associated viral (AAV) particles encoding siRNA molecules and methods for treating Huntington's Disease (HD).