Xin J Wang

US Patent:

6376225, Apr 23, 2002

Filed:

Jan 5, 2001

Appl. No.:

09/754250

Inventors:

Ming-Hui Wei - Germantown MD
Xin Wang - Bethesda MD
Gennady V. Merkulov - Baltimore MD
Valentina Di Francesco - Rockville MD
Ellen M. Beasley - Darnestown MD

Assignee:

PE Corporation (NY) - Norwalk CT

International Classification:

C12N 916

US Classification:

435196, 435 6, 4353201, 536 232

Abstract:

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphodiesterase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphodiesterase peptides, and methods of identifying modulators of the phosphodiesterase peptides.

US Patent:

6602979, Aug 5, 2003

Filed:

Dec 19, 1994

Appl. No.:

08/359316

Inventors:

Curtis C. Harris - Bethesda MD
Xin Wei Wang - North Potomac MD
Jan H. J. Hoeijmakers - Zevenhuizen, NL

Assignee:

The United States of America as represented by the Department of Health and Human Services - Washington DC

International Classification:

C07K 1400

US Classification:

530326, 530350, 514 13

Abstract:

This invention relates to methods of screening for compounds capable of inducing apoptosis in certain tumor cells. The invention also relates to compounds identified by such methods. In addition, the invention relates to methods for the in vitro diagnosis of Xeroderma pigmentosum and compounds useful in these methods.

US Patent:

6613318, Sep 2, 2003

Filed:

Mar 24, 2000

Appl. No.:

09/534811

Inventors:

Xin Wei Wang - Rockville MD
Curtis C. Harris - Garrett Park MD
Jill D. Coursen - Boston MA
Qimin Zhan - Pittsburgh PA

Assignee:

The United States of America as represented by the Department of Health and Human Services - Washington DC

International Classification:

A61K 4500

US Classification:

424 851, 435 6, 435 71, 514 12, 530350, 530386, 5303881

Abstract:

The present invention is directed to novel methods for assaying for modulators of GADD45 polypeptide activity. The invention also provides means to sensitize a proliferating cell to a DNA base-damaging agent by administration of novel inhibitors of GADD45 polypeptide activity. The invention further provides polypeptides which interfere with the ability of Cdc2/cyclin B1 complexes to cause a pause at the G2/M stage of the cell cycle in response to GADD45, and nucleic acids which encode such polypeptides.

US Patent:

6613883, Sep 2, 2003

Filed:

Feb 12, 1999

Appl. No.:

09/248776

Inventors:

Curtis C. Harris - Bethesda MD
Xin Wei Wang - North Potomac MD
Jan H. J. Hoeijmakers - Zevenhuizen, NL

Assignee:

The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC

International Classification:

C07K 700

US Classification:

530358, 530350, 530300, 530324, 530326, 530327, 514 2, 514 12, 514 15, 514 13, 4241851, 4242771

Abstract:

This invention relates to methods of screening for compounds capable of inducing apoptosis in certain tumor cells. The invention also relates to compounds identified by such methods. In addition, the invention relates to methods for the in vitro diagnosis of and compounds useful in these methods.

US Patent:

6754642, Jun 22, 2004

Filed:

May 31, 2001

Appl. No.:

09/867745

Inventors:

Bijan Tadayon - Germantown MD
Aram Nahidipour - Mill Creek WA
Xin Wang - Los Angeles CA
Michael C. Raley - Downey CA
Guillermo Lao - Torrance CA
Thanh T. Ta - Huntington Beach CA
Charles P. Gilliam - Darien CT

Assignee:

Contentguard Holdings, Inc. - Wilmington DE

International Classification:

G06F 1760

US Classification:

705 51, 705 1, 705 54

Abstract:

Usage rights to digital content are dynamically assigned. Various dynamic conditions are monitored and the usage rights are adjusted in a predetermined manner based on the status of dynamic conditions. The dynamic conditions include the time of day, the load on a server or network, or the like. The resolution of an image can be determined based on the conditions and the image can be rendered using subband decomposition techniques to permit variable resolution images to be constructed on the fly.

US Patent:

6867029, Mar 15, 2005

Filed:

Mar 12, 2002

Appl. No.:

10/094989

Inventors:

Ming-Hui Wei - Germantown MD, US
Xin Wang - Bethesda MD, US
Gennady V. Merkulov - Baltimore MD, US
Valentina Di Francesco - Rockville MD, US
Ellen M. Beasley - Darnestown MD, US

Assignee:

Applera Corporation - Norwalk CT

International Classification:

C12N009/22

US Classification:

435196

Abstract:

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphodiesterase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphodiesterase peptides, and methods of identifying modulators of the phosphodiesterase peptides.

US Patent:

6876984, Apr 5, 2005

Filed:

May 31, 2001

Appl. No.:

09/867747

Inventors:

Bijan Tadayon - Germantown MD, US
Aram Nahidipour - Mill Creek WA, US
Xin Wang - Los Angeles CA, US
Michael C. Raley - Downey CA, US
Guillermo Lao - Torrance CA, US
Thanh T. Ta - Huntington Beach CA, US

Assignee:

ContentGuard Holdings, Inc. - Wilmington DE

International Classification:

G06F017/60

US Classification:

705 51, 705 26, 713182

Abstract:

Usage rights for a digital work are established prior to creation of the corresponding content. The rights can be associated with the content after the content is created. A content creation, such as a video recorder or a still camera, device can store labels of the rights and can associate usage rights with content in real time as the content is created.

US Patent:

6895503, May 17, 2005

Filed:

May 31, 2001

Appl. No.:

09/867748

Inventors:

Bijan Tadayon - Germantown MD, US
Aram Nahidipour - Mill Creek WA, US
Xin Wang - Los Angeles CA, US
Michael C. Raley - Downey CA, US
Guillermo Lao - Torrance CA, US
Thanh T. Ta - Huntington Beach CA, US

Assignee:

ContentGuard Holdings, Inc. - Wilmington DE

International Classification:

G06F001/24

US Classification:

713168, 713182, 713193, 713200, 713201

Abstract:

Digital rights management allows one or more of usage rights and delegation rights to be associated with a document. Through the use of the usage rights and the delegation rights, a hierarchy of rights associated with a document is created that provides a tree-type structure of rights extending from the content owner down through one or more users.