- Baltimore MD, US David Gracias - Baltimore MD, US Jayson Pagaduan - Windsor MD, US Anil Bhatta - Baltimore MD, US Xing Chen - Baltimore MD, US Qianru Jin - Cambridge MA, US
International Classification:
G01N 33/50 C12N 5/077 C12N 5/071 B01L 3/00
Abstract:
In one aspect, provided is a composition (biomimetic composition) that includes a biomimetic in vitro model of an arteriolar vessel comprising: at least one of 1) human smooth muscle cells and 2) human pulmonary endothelial cells; wherein the vessel recapitulates one or more of the overall tubular geometry, morphometrics, extracellular matrix constituents, cellular morphology, cellular alignment, and functional heterotypic connections between the human smooth muscle cells and/or the human endothelial cells as compared to an in vivo arteriolar vessel. A microfluidics-based model platform of the pulmonary circulation is provided. Methods of use include measuring flow in biomimetic vessels, and to determine the resistance of these biomimetic vessels in the setting of a variety of experimental conditions that recapitulate the pathobiology of pulmonary hypertension.
Bank of America
Quantitative Finance Analyst
George Washington University Aug 2012 - May 2016
Teaching Assistant
George Washington University Feb 2011 - Dec 2011
Consulting Research Assistant
Marketing Department Gilbarco Company Feb 2010 - Jun 2010
Marketing Intern
Education:
The George Washington University 2012 - 2016
Doctorates, Doctor of Philosophy, Statistics, Philosophy
The George Washington University May 2012
Master of Science, Masters
The George Washington University 2010 - 2012
Masters, Statistics
Capital University of Economics and Business May 2010
Bachelors, Bachelor of Science
Skills:
Data Analysis Statistical Modeling Big Data Analytics Statistical Sampling Data Mining Research Leadership Sas Programming R Microsoft Office Microsoft Word Powerpoint Microsoft Excel
2011 to 2000 Senior Analyst Schedule PlanningFEDERAL AVIATION ADMINSTRATION (FAA) Washington, DC 2006 to 2011 Operation Research AnalystNATIONAL CENTER OF EXCELLENCE FOR AVIATION OPERATIONS RESEARCH (NEXTOR) Berkeley, CA 2005 to 2006 Graduate Research Assistant
Education:
NEW YORK UNIVERSITY New York, NY Jan 2015 Master of Business Administration in SpecializationsUNIVERSITY OF CALIFORNIA, BERKELEY Berkeley, CA Jun 2014UC Berkeley 2001