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Research Scientist, Software Engineer
Intel Corporation Jun 2015 - Aug 2015
Wireless Research Intern
Rice University Jun 2015 - Aug 2015
Research Assistant
Education:
Rice University 2013 - 2018
Doctorates, Doctor of Philosophy, Electronics, Electronics Engineering, Philosophy
University of Electronic Science and Technology of China 2009 - 2013
Bachelor of Engineering, Bachelors, Electronics Engineering
Skills:
Wireless Networking Mathematics Information Theory Matlab Programming Software Development
Institute of Metal Research Chinese Academy of Sciences
Professor
Rice University Aug 2011 - May 2013
Post-Doctoral Research Associate
University of California, San Diego Apr 2008 - Aug 2011
Post-Doctoral Research Fellow
Provex Technologies Aug 2007 - Mar 2008
Research Scientist
University of California, San Diego Sep 2003 - Dec 2007
Research Assistant
Education:
Uc San Diego 2003 - 2007
Doctorates, Doctor of Philosophy, Materials Science, Engineering
University of Science and Technology of China 1999 - 2003
Bachelors, Bachelor of Science, Materials Science, Engineering
Skills:
Polymer Synthesis Hydrogel Preparation Hydrothermal Synthesis Sol Gel Synthesis Wet Chemical Precipitation Solid State Reactions Cell Culture and Tissue Culture Real Time Pcr Western Blots and Gel Electrophoresis Immunochemistry Staining and He Staining Optical and Confocal Microscopy Scanning Electron Microscopy Transmission Electron Microscopy Atomic Force Microscopy Thermal Analysis Tg Dta Dsc Tma Mechanical Tests Compression Tension Bending Failure Hardness Nmr Spectroscopy Mass Spectrometry Gel Permeation Chromatography Ftir Uv/Vis Powder X Ray Diffraction Particle Size Analysis Photolithography Microfabrication Organ Decellularization Polymers Afm Characterization Tem Materials Tissue Engineering Biomaterials Sol Gel Materials Science Cad Particle Size Measurement Chemical Analysis Cell Culture Biomedical Engineering Mechanical Testing Mechanical Tests X Ray Diffraction Photolithography and Microfabrication Perfusion and Decellularization Cad Design Doe Experimental Design
Xiaodong Cheng - Decatur GA, US Xing Zhang - Decatur GA, US
Assignee:
Emory University - Atlanta GA
International Classification:
C40B 30/02 C40B 30/06 C40B 40/10
US Classification:
435007100, 514012000, 702019000
Abstract:
The present invention relates to novel druggable regions discovered in histone H3 lysine methyltransferase DIM-5, which is a SET domain protein. The present invention further relates to methods of using the druggable regions to screen potential candidate therapeutics for diseases in which the activity of SET domain proteins are implicated, for example, anti-cancer/anti-proliferative agents or anti-fungal agents.
Small Molecule Inhibitors Of Bacterial Dam Dna Methyltransferases
Xiaodong Cheng - Decatur GA, US John R. Horton - Stone Mountain GA, US Zhe Yang - Atlanta GA, US Daniel Kalman - Atlanta GA, US Xing Zhang - Decatur GA, US Stanley Hattman - Rochester NY, US Albert Jeltsch - Ritterhude, DE
International Classification:
A61K 31/427 G06G 7/60 C12N 9/10 A61P 31/04
US Classification:
514370, 703 11, 435193
Abstract:
Disclosed are compounds, crystal structures, data representations, methods of using, and methods of identifying compounds in relation to DNA methylation and inhibition of methylation. In embodiments, DNA methylation is by DNA-adenine methyltransferases (Dam). In an embodiment, compounds are used to treat a host suspected of infection by a pathogenic organism. In an embodiment, virulence of a pathogenic bacterium is modified by treatment with an agent capable of inhibiting a bacterial Dam enzyme. In an embodiment, compounds and methods are disclosed regarding Dam inhibitors.