James L. Thomas - Cedar Crest NM, US Wolfgang G. Rudolph - Albuquerque NM, US Xuejun Liu - Albuquerque NM, US
Assignee:
STC.UNM - Albuquerque NM
International Classification:
G01J 3/00 G01B 9/02
US Classification:
356 51, 356484
Abstract:
The present invention includes a system and method for coherent imaging. The system of the present invention includes a light source adapted to provide coherent light to illuminate a sample resulting in optically mixed coherent signals and a detector adapted to receive the optically mixed coherent signals and produce an output signal in response thereto. The optically mixed coherent signals will be a set of sum and difference frequency combinations of the frequencies in the coherent light. A processor is connected to the detector and adapted to ratio a selected two of the optically mixed coherent signals in response to the output signal received by the detector and to generate an image in response to the ratioed optically mixed coherent signals, which can be displayed for a user.
Synthesis Of 4-Chlorokynurenines And Intermediates
The invention relates to an overall enantio-specific synthesis of 4-chlorokynurenine compounds, in particular L-4-chlorokynurenine, with improved yields. Large-scale syntheses are disclosed. The invention also relates to novel intermediates in the synthesis of L-4-chlorokynurenine.
Glycopyrronium Fatty Acid Salts And Methods Of Making Same
- Canandaigua NY, US Emerich Eisenreich - Claremont CA, US Xuejun Karl Liu - Arcadia CA, US Bingidimi Itute Mobele - Altamont NY, US Satish Goud Puppali - Rancho Cucamonga CA, US
International Classification:
C07D 207/12 C07C 53/126 C07C 57/12 C07C 57/03
Abstract:
Novel glycopyrronium fatty acid salts have been developed. Bi-phasic reaction conditions enable the desired counterion exchange reactions between glycopyrronium bromide and fatty acid salts of alkali metals and alkaline earth metals in methods to form glycopyrronium fatty acid salts. In preferred embodiments, an excess of the free fatty acid in the reaction mixture stabilizes the glycopyrronium fatty acid salt and reduces the formation of the impurity, Acid A. In some preferred embodiments, between 0.2 and 1.2 molar equivalent of excess free fatty acid is added to the reaction mixture. In another embodiment, approximately 1.2 molar equivalent of excess free fatty acid is added to the reaction mixture.