Yanan W Zheng

US Patent:

20100021460, Jan 28, 2010

Filed:

Jul 14, 2009

Appl. No.:

12/502953

Inventors:

Rong Deng - Pleasanton CA, US
Paul J. Fielder - Emerald Hills CA, US
Henry B. Lowman - El Granada CA, US
Eric Stefanich - Redwood City CA, US
Yanan Zheng - Redwood City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

A61K 39/395
A61P 37/00

US Classification:

4241331

Abstract:

Methods of treating autoimmune disorders in mammalian subjects using non-depleting CD4 antibodies, alone or in combination with other compounds, are provided.

US Patent:

20120156194, Jun 21, 2012

Filed:

Dec 16, 2011

Appl. No.:

13/328830

Inventors:

Joseph R. Arron - San Mateo CA, US
Richard W. Erickson - Castro Valley CA, US
Michelle Freemer - Mill Valley CA, US
Meredith Hazen - Belmont CA, US
Guiquan Jia - Foster City CA, US
John G. Matthews - San Francisco CA, US
Wendy Putnam - Belmont CA, US
Heleen Scheerens - Menlo Park CA, US
Yanan Zheng - Redwood City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

A61K 39/395
A61P 11/06
C07H 21/04
C07K 16/18
G01N 33/577
G01N 33/566

US Classification:

4241311, 435 792, 436501, 536 2431, 5303898, 4241581, 4241331

Abstract:

Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.

US Patent:

20140044645, Feb 13, 2014

Filed:

Sep 9, 2013

Appl. No.:

14/021698

Inventors:

Richard W. Erickson - Castro Valley CA, US
Michelle Freemer - Mill Valley CA, US
Meredith Hazen - Belmont CA, US
Guiquan Jia - Foster City CA, US
John G. Matthews - San Francisco CA, US
Wendy Putnam - Belmont CA, US
Heleen Scheerens - Menlo Park CA, US
Yanan Zheng - Redwood City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

G01N 33/68
A61K 39/395
C07K 16/18

US Classification:

424 92, 435 794, 536 2431, 435 611, 5303879, 4241581, 4241331, 4241361

Abstract:

Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.

US Patent:

20140044702, Feb 13, 2014

Filed:

Sep 9, 2013

Appl. No.:

14/021947

Inventors:

Richard W. Erickson - Castro Valley CA, US
Michelle Freemer - Mill Valley CA, US
Meredith Hazen - Belmont CA, US
Guiquan Jia - Foster City CA, US
John G. Matthews - San Francisco CA, US
Wendy Putnam - Belmont CA, US
Heleen Scheerens - Menlo Park CA, US
Yanan Zheng - Redwood City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

G01N 33/68
A61K 31/522
A61K 45/06
A61K 39/395
A61K 31/573

US Classification:

4241311, 435 792, 536 231, 5303898, 4241581, 4241331, 4241361

Abstract:

Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.

US Patent:

20070071681, Mar 29, 2007

Filed:

Mar 15, 2006

Appl. No.:

11/377614

Inventors:

Kapil Gadkar - Foster City CA, US
Huub Kreuwel - San Francisco CA, US
Thomas Paterson - Redondo Beach CA, US
David Polidori - Rancho Santa Fe CA, US
Saroja Ramanujan - Daly City CA, US
Lisl Katharine Mie Shoda - Menlo Park CA, US
Chan Whiting - San Jose CA, US
Daniel Young - San Francisco CA, US
Yanan Zheng - Foster City CA, US

International Classification:

A61K 49/00
G06F 19/00
G06Q 50/00

US Classification:

424009200, 702019000, 705003000

Abstract:

The invention encompasses novel methods for developing a computer model of type 1 diabetes in a mammal. In particular, the models can include representations of biological processes associated with a pancreatic lymph node and one or more pancreatic islets. Alternatively, the models can include representations of biological processes associated with at least two conditions selected from the group consisting of autoreactive T cell production, autoreactive T cell priming, insulitis and hyperglycemia. The invention also provides methods for developing a computer model of a non-insulin replacement treatment of type 1 diabetes. The invention also encompasses computer models of type 1 diabetes, methods of simulating type 1 diabetes and computer systems for simulating type 1 diabetes and the uses thereof.

US Patent:

20220372131, Nov 24, 2022

Filed:

Aug 8, 2022

Appl. No.:

17/882932

Inventors:

- South San Francisco CA, US
Theodore A. Omachi - South San Francisco CA, US
Ryan P. Owen - South San Francisco CA, US
Karl Yen - South San Francisco CA, US
Yanan Zheng - Cupertino CA, US
Kendra Debusk - New Hope PA, US

International Classification:

C07K 16/24
A61P 17/00
A61K 9/00
A61K 9/19
A61K 31/573
A61K 39/395

Abstract:

Uses of IL-13 antagonists for treating atopic dermatitis are provided. Also provided are methods of treating atopic dermatitis and methods of reducing the severity of atopic dermatitis by administering IL-13 antagonists.

US Patent:

20190270803, Sep 5, 2019

Filed:

Mar 18, 2019

Appl. No.:

16/356309

Inventors:

- South San Francisco CA, US
Theodore A. Omachi - South San Francisco CA, US
Ryan P. Owen - South San Francisco CA, US
Karl Yen - South San Francisco CA, US
Yanan Zheng - Cupertino CA, US
Kendra Debusk - New Hope PA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C07K 16/24
A61K 31/573
A61K 9/00
A61K 9/19
A61P 17/00

Abstract:

Uses of IL-13 antagonists for treating atopic dermatitis are provided. Also provided are methods of treating atopic dermatitis and methods of reducing the severity of atopic dermatitis by administering IL-13 antagonists.